科研成果

2014
Zhou Z, Jia X, Xue Q, Dou Z, Ma Y, Zhao Z, Jiang ZF, He B, Jin Q, Wang J. TRIM14 is a mitochondrial adaptor that facilitates retinoic acid-inducible gene-I-like receptor-mediatedinnate immune response. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2014;(2):E245-E254. 访问链接
2013
Chen H, Jiang ZF. The essential adaptors of innate immune signaling. Protein and Cell [Internet]. 2013;(1):27-39. 访问链接
2012
Arnold CN, Barnes MJ, Berger M, Blasius AL, Brandl K, Croker B, Crozat K, Du X, Eidenschenk C, Georgel P, et al. ENU-induced phenovariance in mice: Inferences from 587 mutations. BMC Research Notes [Internet]. 2012. 访问链接
Zhou X, You F, Chen H, Jiang ZF. Poly(C)-binding protein 1 (PCBP1) mediates housekeeping degradation of mitochondrial antiviral signaling (MAVS). Cell Research [Internet]. 2012;(4):717-727. 访问链接
Huang Y-H, Liu X-Y, Du X-X, Jiang Z-F, Su X-D. The structural basis for the sensing and binding of cyclic di-GMP by STING. Nature Structural and Molecular Biology [Internet]. 2012;(7):728-730. 访问链接
2011
Chen H, Sun H, You F, Sun W, Zhou X, Chen L, Yang J, Wang Y, Tang H, Guan Y, et al. Activation of STAT6 by STING is critical for antiviral innate immunity. Cell [Internet]. 2011;(2):436-446. 访问链接
2009
You F, Sun H, Zhou X, Sun W, Liang S, Zhai Z, Jiang ZF. PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. Nature Immunology [Internet]. 2009;(12):1300-1308. 访问链接
Sun W, Li Y, Chen L, Chen H, You F, Zhou X, Zhou Y, Zhai Z, Chen D, Jiang ZF. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2009;(21):8653-8658. 访问链接
Gao D, Yang Y-K, Wang R-P, Zhou X, Diao F-C, Li M-D, Zhai Z-H, Jiang Z-F, Chen D-Y. REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I. PLoS ONE [Internet]. 2009;(6). 访问链接
2008
Xiao H, Qian W, Staschke K, Qian Y, Cui G, Deng L, Ehsani M, Wang X, Qian Y-W, Chen ZJ, et al. Pellino 3b negatively regulates interleukin-1-induced TAK1-dependent NFκB activation. Journal of Biological Chemistry [Internet]. 2008;(21):14654-14664. 访问链接
Schabbauer G, Luyendyk J, Crozat K, Jiang ZF, Mackman N, Bahram S, Georgel P. TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages. Molecular Immunology [Internet]. 2008;(10):2790-2796. 访问链接
2007
Otsuka M, Jing Q, Georgel P, New L, Chen J, Mols J, Kang Y J, Jiang ZF, Du X, Cook R, et al. Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression. Immunity [Internet]. 2007;(1):123-134. 访问链接
Yao J, Tae WK, Qin J, Jiang ZF, Qian Y, Xiao H, Lu Y, Qian W, Gulen MF, Sizemore N, et al. Interleukin-1 (IL-1)-induced TAK1-dependent Versus MEKK3-dependent NFκB activation pathways bifurcate at IL-1 receptor-associated kinase modification. Journal of Biological Chemistry [Internet]. 2007;(9):6075-6089. 访问链接
Georgel P, Jiang ZF, Kunz S, Janssen E, Mols J, Hoebe K, Bahram S, Oldstone MBA, Beutler B. Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway. Virology [Internet]. 2007;(2):304-313. 访问链接
2006
Jiang ZF, Georgel P, Li C, Choe J, Crozat K, Rutschmann S, Du X, Bigby T, Mudd S, Sovath S, et al. Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2006;(29):10961-10966. 访问链接
Hoebe K, Jiang Z, Georgel P, Tabeta K, Janssen E, Du X, Beutler B. TLR signaling pathways: Opportunities for activation and blockade in pursuit of therapy. Current Pharmaceutical Design [Internet]. 2006;(32):4123-4134. 访问链接
Huber M, Kalis C, Keck S, Jiang ZF, Georgel P, Du X, Shamel L, Sovath S, Mudd S, Beutler B, et al. R-form LPS, the master key to the activation of TLR4/MD-2-positive cells. European Journal of Immunology [Internet]. 2006;(3):701-711. 访问链接
2005
Zhou Z, Hoebe K, Du X, Jiang ZF, Shamel L, Beutler B. Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation. European Journal of Immunology [Internet]. 2005;(6):1918-1927. 访问链接
Jiang ZF, Georgel P, Du X, Shamel L, Sovath S, Mudd S, Huber M, Kalis C, Keck S, Galanos C, et al. CD14 is required for MyD88-independent LPS signaling. Nature Immunology [Internet]. 2005;(6):565-570. 访问链接
Beutler B, Georgel P, Rutschmann S, Jiang ZF, Croker B, Crozat K. Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV). Briefings in Functional Genomics and Proteomics [Internet]. 2005;(3):203-213. 访问链接

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