科研成果

2014
Wang J, Xiao R. G protein-coupled receptors in energy homeostasis. Science China Life Sciences. 2014;(7):672-680.
Woo AY-H, Jozwiak K, Toll L, Tanga MJ, Kozocas JA, Jimenez L, Huang Y, Song Y, Plazinska A, Pajak K, et al. Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor. Journal of Biological Chemistry [Internet]. 2014;(28):19351-19363. 访问链接
Zhang X, Xu J, Cai X, Ji L, Li J, Cao B, Li J, Hu D, Li Y, Wang H, et al. Acute insulin resistance mediated by advanced glycation endproducts in severely burned rats. Critical Care Medicine [Internet]. 2014;(6):e472-e480. 访问链接
2013
Whelan RS, Konstantinidis K, Xiao RP, Kitsis RN. Erratum: Cardiomyocyte life-death decisions in response to chronic β-adrenergic signaling (Circulation Research (2013) 112 (408-410) DOI: 10.1161/CIRCRESAHA.113.300805). Circulation Research. 2013;(12):e181.
Xiao R-P. Bioimaging for cardiometabolic translational medicine: From cellular messengers to organism function. Journal of Molecular Medicine [Internet]. 2013;(8):905-906. 访问链接
Whelan RS, Konstantinidis K, Xiao R-P, Kitsis RN. Cardiomyocyte life-death decisions in response to chronic β-adrenergic signaling. Circulation Research [Internet]. 2013;(3):408-410. 访问链接
Song R, Peng W, Zhang Y, Lv F, Wu H-K, Guo J, Cao Y, Pi Y, Zhang X, Jin L, et al. Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders. Nature [Internet]. 2013;(7437):375-379. 访问链接
Tae H-J, Kim JM, Park S, Tomiya N, Li G, Wei W, Petrashevskaya N, Ahmet I, Pang J, Cruschwitz S, et al. The N-glycoform of sRAGE is the key determinant for its therapeutic efficacy to attenuate injury-elicited arterial inflammation and neointimal growth. Journal of Molecular Medicine [Internet]. 2013;(12):1369-1381. 访问链接
Liu W, Zi M, Tsui H, Chowdhury SK, Zeef L, Meng Q-J, Travis M, Prehar S, Berry A, Hanley NA, et al. A novel immunomodulator, FTY-720 reverses existing cardiac hypertrophy and fibrosis from pressure overload by targeting NFAT (nuclear factor of activated T-cells) signaling and periostin. Circulation: Heart Failure [Internet]. 2013;(4):833-844. 访问链接
Zhang S-J, Liu C-J, Shi M, Kong L, Chen J-Y, Zhou W-Z, Zhu X, Yu P, Wang J, Yang X, et al. RhesusBase: A knowledgebase for the monkey research community. Nucleic Acids Research [Internet]. 2013;(D1):D892-D905. 访问链接
2012
Zhao T, Huang X, Han L, Wang X, Cheng H, Zhao Y, Chen Q, Chen J, Cheng H, Xiao R, et al. Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes. Journal of Biological Chemistry [Internet]. 2012;(28):23615-23625. 访问链接
Zhang Y, Zhang T, Cao C-M, Xiao R-P. MTOR: good, bad, orugly?. Cardiovascular Research [Internet]. 2012;(3):261-262. 访问链接
Weisleder N, Takizawa N, Lin P, Wang X, Cao C, Zhang Y, Tan T, Ferrante C, Zhu H, Chen P-J, et al. Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Science Translational Medicine [Internet]. 2012;(139). 访问链接
Zhu W, Petrashevskaya N, Ren S, Zhao A, Chakir K, Gao E, Chuprun KJ, Wang Y, Talan M, Dorn GW, et al. Gi-biased β2AR signaling links GRK2 upregulation to heart failure. Circulation Research [Internet]. 2012;(2):265-274. 访问链接
Xu EH, Xiao R-P. A new era for GPCR research: Structures, biology and drug discovery. Acta Pharmacologica Sinica [Internet]. 2012;(3):289-290. 访问链接
Lin P, Zhu H, Cai C, Wang X, Cao C, Xiao R, Pan Z, Weisleder N, Takeshima H, Jianjie M. Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair. FASEB Journal [Internet]. 2012;(5):1875-1883. 访问链接
Woo AYH, Xiao R-P. β-Adrenergic receptor subtype signaling in heart: From bench to bedside. Acta Pharmacologica Sinica [Internet]. 2012;(3):335-341. 访问链接
2011
Jozwiak K, Plazinska A, Toll L, Jimenez L, Woo AY-H, Xiao R-P, Wainer IW. Effect of fenoterol stereochemistry on the β2 adrenergic receptor system: Ligand-directed chiral recognition. Chirality [Internet]. 2011;(1 E):E1-E6. 访问链接
Chakir K, Depry C, Dimaano VL, Zhu W-Z, Vanderheyden M, Bartunek J, Abraham TP, Tomaselli GF, Liu S-B, Xiang YK, et al. Gαs-biased β2-adrenergic receptor signaling from restoring synchronous contraction in the failing heart. Science Translational Medicine [Internet]. 2011;(100). 访问链接
Xu KY, Zhu W, Chen L, DeFilippi C, Zhang J, Xiao R-P. Mechanistic distinction between activation and inhibition of (Na++K+)-ATPase-mediated Ca2+ influx in cardiomyocytes. Biochemical and Biophysical Research Communications [Internet]. 2011;(2):200-203. 访问链接

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