科研成果

2002
Hagemann D, Xiao R-P. Dual site phospholamban phosphorylation and its physiological relevance in the heart. Trends in Cardiovascular Medicine [Internet]. 2002;(2):51-56. 访问链接 SCI被引用次数:76.
Jo S-H, Leblais V, Wang PH, Crow MT, Xiao R-P. Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent Gs signaling during β2-adrenergic stimulation. Circulation Research [Internet]. 2002;(1):46-53. 访问链接 SCI被引用次数:94.
Lavoie C, Mercier J-F, Salahpour A, Umapathy D, Breit A, Villeneuve L-R, Zhu W-Z, Xiao R-P, Lakatta EG, Bouvier M, et al. β1/β2-adrenergic receptor heterodimerization regulates β2-adrenergic receptor internalization and ERK signaling efficacy. Journal of Biological Chemistry [Internet]. 2002;(38):35402-35410. 访问链接 SCI被引用次数:169.
Song L-S, Guia A, Muth JN, Rubio M, Wang S-Q, Xiao R-P, Josephson IR, Lakatta EG, Schwartz A, Cheng H. Ca2+ signaling in cardiac myocytes overexpressing the α1 subunit of L-type Ca2+ channel. Circulation Research [Internet]. 2002;(2):174-181. 访问链接 SCI被引用次数:44.
Liao P, Wang S-Q, Wang S, Zheng M, Zheng M, Zhang S-J, Cheng H, Wang Y, Xiao R-P. p38 mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes. Circulation Research [Internet]. 2002;(2):190-196. 访问链接 SCI被引用次数:127.
2001
Xiao RP. Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins. Science"s STKE [electronic resource] : signal transduction knowledge environment [Internet]. 2001;(104):RE15. 访问链接
Zhu W-Z, Zheng M, Koch WJ, Lefkowitz RJ, Kobilka BK, Xiao R-P. Dual modulation of cell survival and cell death by β2-adrenergic signaling in adult mouse cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2001;(4):1607-1612. 访问链接 SCI被引用次数:306.
Liao P, Georgakopoulos D, Kovacs A, Zheng M, Lerner D, Pu H, Saffitz J, Chien K, Xiao R-P, Kass DA, et al. The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2001;(21):12283-12288. 访问链接 SCI被引用次数:233.
Song L-S, Wang S-Q, Xiao R-P, Spurgeon H, Lakatta EG, Cheng H. β-adrenergic stimulation synchronizes intracellular Ca 2+ release during excitation-contraction coupling in cardiac myocytes. Circulation Research [Internet]. 2001;(8):794-801. 访问链接 SCI被引用次数:117.
2000
Zhou Y-Y, Wang S-Q, Zhu W-Z, Chruscinski A, Kobilka BK, Ziman B, Wang S, Lakatta EG, Cheng H, Xiao R-P. Erratum: Culture and adenoviral infection of adult mouse cardiac myocytes: Methods for cellular genetic physiology (American Journal of Physiology - Heart and Circulatory Physiology (July 2000) 279:48 (H429-H436)). American Journal of Physiology - Heart and Circulatory Physiology. 2000;(4 48-4):x.
Ye C-I, Xiao R-P, Izu LT, Cheng H, Kuschel M, Spurgeon H, Lakatta EG. G(i)-dependent localization of β2-adrenergic receptor signaling to L-type Ca2+ channels. Biophysical Journal [Internet]. 2000;(5):2547-2556. 访问链接
Vinogradova TM, Zhou Y-Y, Bogdanov KY, Yang D, Kuschel M, Cheng H, Xiao R-P. Sinoatrial node pacemaker activity requires Ca2+/calmodulin-dependent protein kinase II activation. Circulation Research [Internet]. 2000;(9):760-767. 访问链接 SCI被引用次数:115.
Zhou Y-Y, Yang D, Zhu W-Z, Zhang S-J, Wang D-J, Rohrer DK, Devic E, Kobilka BK, Lakatta EG, Cheng H, et al. Spontaneous activation of β2- but not β1-adrenoceptors expressed in cardiac myocytes from β1β2 double knockout mice. Molecular Pharmacology [Internet]. 2000;(5):887-894. 访问链接
Chesley A, Lundberg MS, Asai T, Xiao R-P, Ohtani S, Lakatta EG, Crow MT. The β2-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through G(i)-dependent coupling to phosphatidylinositol 3'-kinase. Circulation Research [Internet]. 2000;(12):1172-1179. 访问链接 SCI被引用次数:283.
Xiao R-P. Cell logic for dual coupling of a single class of receptors to G(s) and G(i) proteins. Circulation Research [Internet]. 2000;(8):635-637. 访问链接 SCI被引用次数:27.
Zhou Y-Y, Wang S-Q, Zhu W-Z, Chruscinski A, Kobilka BK, Ziman B, Wang S, Lakatta EG, Cheng H, Xiao R-P. Culture and adenoviral infection of adult mouse cardiac myocytes: Methods for cellular genetic physiology. American Journal of Physiology - Heart and Circulatory Physiology [Internet]. 2000;(1 48-1):H429-H436. 访问链接 SCI被引用次数:227.
Hagemann D, Kuschel M, Kuramochi T, Zhu W, Cheng H, Xiao R-P. Frequency-encoding Thr17 phospholamban phosphorylation is independent of Ser16 phosphorylation in cardiac myocytes. Journal of Biological Chemistry [Internet]. 2000;(29):22532-22536. 访问链接 SCI被引用次数:108.
Zhang S-J, Cheng H, Zhou Y-Y, Wang D-J, Zhu W, Ziman B, Spurgoen H, Lefkowitz RJ, Lakatta EG, Koch WJ, et al. Inhibition of spontaneous β2-adrenergic activation rescues β1- adrenergic contractile response in cardiomyocytes overexpressing β2- adrenoceptor. Journal of Biological Chemistry [Internet]. 2000;(28):21773-21779. 访问链接 SCI被引用次数:21.
Zheng M, Zhang S-J, Zhu W-Z, Ziman B, Kobilka BK, Xiao R-P. β2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or Gβγ in adult mouse cardiomyocytes. Journal of Biological Chemistry [Internet]. 2000;(51):40635-40640. 访问链接
1999
Zhou Y-Y, Lakatta EG, Xiao R-P. Calcium cycling in the aged heart. Asia Pacific Heart Journal. 1999;(2):88-96.

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