科研成果

2005
Fan K, Ma L, Han X, Liang H, Wei P, Liu Y, Lai L. The substrate specificity of SARS coronavirus 3C-like proteinase. Biochemical and Biophysical Research Communications [Internet]. 2005;(3):934-940. 访问链接
Lu R-C, Xiao J-X, Cao A-N, Lai L-H, Zhu B-Y, Zhao G-X. Surfactant-induced refolding of lysozyme. Biochimica et Biophysica Acta - General Subjects [Internet]. 2005;(3):271-281. 访问链接
Liu Z, Huang C, Fan K, Wei P, Chen H, Liu S, Pei J, Shi L, Li B, Yang K, et al. Virtual screening of novel noncovalent inhibitors for SARS-CoV 3C-like proteinase. Journal of Chemical Information and Modeling [Internet]. 2005;(1):10-17. 访问链接
2004
Gao Y, Lai L-H. Analysis of protein-protein interface. Acta Physico - Chimica Sinica. 2004;(7):676-679.
Zhong W, Yu J-S, Liang Y, Fan K, Lai L. Chlorobenzylidine-calf thymus DNA interaction II: Circular dichroism and nuclear magnetic resonance studies. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy [Internet]. 2004;(13):2985-2992. 访问链接
Huang C, Wei P, Fan K, Liu Y, Lai L. 3C-like Proteinase from SARS Coronavirus Catalyzes Substrate Hydrolysis by a General Base Mechanism. Biochemistry [Internet]. 2004;(15):4568-4574. 访问链接
Fan K, Wei P, Feng Q, Chen S, Huang C, Ma L, Lai B, Pei J, Liu Y, Chen J, et al. Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase. Journal of Biological Chemistry [Internet]. 2004;(3):1637-1642. 访问链接
Pei J, Wang Q, Zhou J, Lai L. Estimating protein-ligand binding free energy: Atomic solvation parameters for partition coefficient and solvation free energy calculation. Proteins: Structure, Function and Genetics [Internet]. 2004;(4):651-664. 访问链接
Cao A, Hu D, Lai L. Formation of amyloid fibrils from fully reduced hen egg white lysozyme. Protein Science [Internet]. 2004;(2):319-324. 访问链接
Gao Y, Wang R, Lai L. Structure-based method for analyzing protein-protein interfaces. Journal of Molecular Modeling [Internet]. 2004;(1):44-54. 访问链接
Yuan K, Yi L, Chen J, Qu X, Qing T, Rao X, Jiang P, Hu J, Xiong Z, Nie Y, et al. Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein. Biochemical and Biophysical Research Communications [Internet]. 2004;(3):746-752. 访问链接
2003
Han X-F, Liu Y, Gao Y, Lai L-H. Comparative molecular field analysis of non-peptidic inhibitors of thrombin. Acta Chimica Sinica. 2003;(7):1136-1139.
Wang X, Deng W, Cao A-N, Lai L-H. Molecular recognition of GCN4 monomeric peptide tryptophane mutant with its DNA target sites. Acta Physico - Chimica Sinica. 2003;(9):834-838.
Fu X, Wang Y, Huang L, Sha Y, Gui L, Lai L, Tang Y. Assemblies of metal nanoparticles and self-assembled peptide fibrils - Formation of double helical and single-chain arrays of metal nanoparticles. Advanced Materials. 2003;(11):902-906.
Huang C-K, Gao Y, Liu Z-M, Liu Y, Lai L-H. Comparative molecular field analysis of pyrrolidine inhibitors for human cytosolic phospholipase A2. Acta Physico - Chimica Sinica. 2003;(1):79-81.
Zou X-J, Lai L-H, Jin G-Y, Huang G-Q. Synthesis, plant growth regulating effect and QSAR of a series of 1-aryl-1,4-dihydro-3-acylhydrazinocarbonyl-6-methyl-4-pyridazinones. Chinese Journal of Organic Chemistry. 2003;(6):550-554.
Zhai X, Li J, Brezesinski G, He Q, Möhwald H, Lai L, Liu Y, Liu L, Gao Y. Direct observations of the cleavage reaction of an L-DPPC monolayer catalyzed by phospholipase A2 and inhibited by an indole inhibitor at the air/water interface. ChemBioChem [Internet]. 2003;(4):299-305. 访问链接
Kim R, Lai L, Lee H-H, Cheong G-W, Kim KK, Wu Z, Yokota H, Marqusee S, Kim S-H. On the mechanism of chaperone activity of the small heat-shock protein of Methanococcus jannaschii. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2003;(14):8151-8155. 访问链接
Liu S, Pei J, Chen H, Zhu X, Liu Z, Ma W, He F, Lai L. Modeling of the SARS coronavirus main proteinase and conformational flexibility of the active site. Beijing Da Xue Xue Bao [Internet]. 2003:62-65. 访问链接
Wang X, Cao W, Cao A, Lai L. Thermodynamic characterization of the folding coupled DNA binding by the monomeric transcription activator GCN4 peptide. Biophysical Journal [Internet]. 2003;(3):1867-1875. 访问链接

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