科研成果

2003
Liu Z, Jiang L, Gao Y, Liang S, Chen H, Han Y, Lai L. Beyond the rotamer library: Genetic algorithm combined with the disturbing mutation process for upbuilding protein side-chains. Proteins: Structure, Function and Genetics [Internet]. 2003;(1):49-62. 访问链接
Lai B, Li Y, Cao A, Lai L. Metal ion binding and enzymatic mechanism of Methanococcus jannaschii RNase HII. Biochemistry [Internet]. 2003;(3):785-791. 访问链接
2002
Sha Y-L, Li Y-L, Qiu Y, Wang Q, Lai L-H, Tang Y-qi. de novo design and conformational studies of a β-hairpin forming peptide. Acta Physico - Chimica Sinica. 2002;(10):907-910.
Gao Y, Wang R-X, Lai L-H. New method to analyze protein-protein interaction interface. Acta Physico - Chimica Sinica. 2002;(8):676-679.
Zou X-J, Lai L-H, Jin G-Y, Huang G-Q. Studies on the 3D-QSAR of novel 1-aryl-1, 4-dihydro-3-Acylhydrazinocarbonyl-6-methyl-4-pyridazinones. Acta Physico - Chimica Sinica. 2002;(6):513-516.
Jiang L, Lai L. CH⋯O hydrogen bonds at protein-protein interfaces. Journal of Biological Chemistry [Internet]. 2002;(40):37732-37740. 访问链接
Wang R, Lai L, Wang S. Further development and validation of empirical scoring functions for structure-based binding affinity prediction. Journal of Computer-Aided Molecular Design [Internet]. 2002;(1):11-26. 访问链接
Cao A, Wang G, Tang Y, Lai L. Linear correlation between thermal stability and folding kinetics of lysozyme. Biochemical and Biophysical Research Communications [Internet]. 2002;(4):795-797. 访问链接
Cai L, Cao A, Lai L. Monitoring the kinetics and thermodynamics of interfacial enzymatic catalysis by differential scanning calorimetry. Biochemical and Biophysical Research Communications [Internet]. 2002;(3):446-451. 访问链接
Jiang L, Gao Y, Mao F, Liu Z, Lai L. Potential of mean force for protein-protein interaction studies. Proteins: Structure, Function and Genetics [Internet]. 2002;(2):190-196. 访问链接
Zou X-J, Lai L-H, Jin G-Y, Zhang Z-X. Synthesis, fungicidal activity, and 3D-QSAR of pyridazinone-substituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles. Journal of Agricultural and Food Chemistry [Internet]. 2002;(13):3757-3760. 访问链接
Gao F, Li Y, Sha Y, Lai L, Wang Y, Wu H, Qiu Y. β-Turn formation by a six-residue linear peptide in solution. Journal of Peptide Research [Internet]. 2002;(2):75-80. 访问链接
2001
Ni L-S, Mao F-L, Han Y-Z, Lai L-H. Low Homologous Protein Structure Prediction. Acta Physico - Chimica Sinica. 2001;(5):392-.
Gao F, Sha Y-L, Qiu Y, Wang Y-F, Li Y-L, Lai L-H, Wu H-M. Solution Conformation Study on a β-turn Forming Peptide. Acta Physico - Chimica Sinica. 2001;(7):621-.
Lai B, Li Y, Cao A-N, Lai L-H. Thermodynamic Study on Binding of Archaebacterial RNase HII and Metal Ions. Acta Physico - Chimica Sinica. 2001;(10):867-.
Liu Y, Feng Y-B, Gao Y, Wang R-X, Lai L-H. Structure-based design and synthesis of novel type quinoline as secretory PLA2 inhibitors. Acta Chimica Sinica. 2001;(10):1751-1755.
Cai L, Cao A, Lai L. An isothermal titration calorimetric method to determine the kinetic parameters of enzyme catalytic reaction by employing the product inhibition as probe. Analytical Biochemistry [Internet]. 2001;(1):19-23. 访问链接
Liu Z, Li W, Zhang H, Han Y, Lai L. Modeling the third loop of short-chain snake venom neurotoxins: Roles of the short-range and long-range interactions. Proteins: Structure, Function and Genetics [Internet]. 2001;(1):6-16. 访问链接
Tao P, Lai L. Protein ligand docking based on empirical method for binding affinity estimation. Journal of Computer-Aided Molecular Design [Internet]. 2001;(5):429-446. 访问链接
Liu Y, Feng Y, Wang R, Gao Y, Lai L. Quinoline-4-acetamides as sPLA 2 inhibitors. Bioorganic and Medicinal Chemistry Letters [Internet]. 2001;(13):1639-1641. 访问链接

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