科研成果

2010
Xiong X, Lu Y, Zhang L, Wang B, Zhao Y, Wang X-J, Huo X, Shen Y, Liang Z, Chen M. Discovery of novel cell proliferation-enhancing gene by random siRNA library based combinatorial screening. Combinatorial Chemistry and High Throughput Screening [Internet]. 2010;(9):798-806. 访问链接
Guo S, Huang Y, Jiang Q, Sun Y, Deng L, Liang Z, Du Q, Xing J, Zhao Y, Wang PC, et al. Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte. ACS Nano [Internet]. 2010;(9):5505-5511. 访问链接 SCI被引用次数:182.
Xiong J, Yu D, Wei N, Fu H, Cai T, Huang Y, Wu C, Zheng X, Du Q, Lin D, et al. An estrogen receptor α suppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples. FEBS Journal [Internet]. 2010;(7):1684-1694. 访问链接 SCI被引用次数:97.
Xiong J, Du Q, Liang Z. Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein. Oncogene [Internet]. 2010;(35):4980-4988. 访问链接 SCI被引用次数:72.
Li J, Liang Z. The consideration of synthetic short interfering RNA for therapeutic use. Basic and Clinical Pharmacology and Toxicology [Internet]. 2010;(1):22-29. 访问链接 SCI被引用次数:4.
Wei Z, Huang H, Wu M, Liang Z, Wang W, Li Z. A high performance continuous electroporation chip. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 2010:1622-1624.
Wei Z, Huang H, Liang Z, Li Z. A high performance electroporation chip integrating multi-well plate and annular interdigital microelectrodes. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010:951-954.
2009
Xue Y, Petrovic N, Cao R, Larsson O, Lim S, Chen S, Feldmann HM, Liang Z, Zhu Z, Nedergaard J, et al. Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation. Cell Metabolism [Internet]. 2009;(1):99-109. 访问链接 SCI被引用次数:123.
Liu X-X, Rocchi P, Qu F-Q, Zheng S-Q, Liang Z-C, Gleave M, Iovanna J, Peng L. PAMAM dendrimers mediate siRNA delivery to target Hsp27 and produce potent antiproliferative effects on prostate cancer cells. ChemMedChem [Internet]. 2009;(8):1302-1310. 访问链接 SCI被引用次数:76.
Huang H, Qiao R, Zhao D, Zhang T, Li Y, Yi F, Lai F, Hong J, Ding X, Yang Z, et al. Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. Nucleic Acids Research [Internet]. 2009;(22):7560-7569. 访问链接 SCI被引用次数:27.
2008
Dahlgren C, Zhang H-Y, Du Q, Grahn M, Norstedt G, Wahlestedt C, Liang Z. Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Research [Internet]. 2008;(9). 访问链接 SCI被引用次数:34.
Hong J, Wei N, Chalk A, Wang J, Song Y, Yi F, Qiao R-P, Sonnhammer ELL, Wahlestedt C, Liang Z, et al. Focusing on RISC assembly in mammalian cells. Biochemical and Biophysical Research Communications [Internet]. 2008;(3):703-708. 访问链接 SCI被引用次数:7.
2007
Chen M, Du Q, Zhang H-Y, Wang X, Liang Z. High-throughput screening using siRNA (RNAi) libraries. Expert Review of Molecular Diagnostics [Internet]. 2007;(3):281-291. 访问链接 SCI被引用次数:8.
Li Z-S, Qiao R-P, Du Q, Yang Z-J, Zhang L-R, Zhang P-Z, Liang Z-C, Zhang L-H. Studies on aminoisonucleoside modified siRNAs: Stability and silencing activity. Bioconjugate Chemistry [Internet]. 2007;(4):1017-1024. 访问链接 SCI被引用次数:12.
2006
Larsson O, Perlman DM, Fan D, Reilly CS, Peterson M, Dahlgren C, Liang Z, Li S, Polunovsky VA, Wahlestedt C, et al. Apoptosis resistance downstream of eIF4E: Posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Research [Internet]. 2006;(16):4375-4386. 访问链接 SCI被引用次数:43.
Zaslavsky A, Singh LS, Tan H, Ding H, Liang Z, Xu Y. Homo- and hetero-dimerization of LPA/S1P receptors, OGR1 and GPR4. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids [Internet]. 2006;(10):1200-1212. 访问链接 SCI被引用次数:45.
Gao Y, Sun L, Dong J, Xu X, Shu Y, Chen M, Yin L, Liang Z, Jin Q. Rapid identification of small interfering RNA that can effectively inhibit the replication of multiple influenza B virus strains. Antiviral Therapy [Internet]. 2006;(4):431-438. 访问链接 SCI被引用次数:6.
Zhang H-Y, Du Q, Wahlestedt C, Liang Z. RNA interference with chemically modified siRNA. Current Topics in Medicinal Chemistry [Internet]. 2006;(9):893-900. 访问链接 SCI被引用次数:32.
2005
Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. Erratum: A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites (Nucleic Acids Research (2005) vol. 33 (1671-1677)). Nucleic Acids Research. 2005;(11):3698-. SCI被引用次数:1.
Liang Z. High-throughput screening using genome-wide siRNA libraries. IDrugs [Internet]. 2005;(11):924-926. 访问链接 SCI被引用次数:3.

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