科研成果

2005
Elmén J, Thonberg H, Ljungberg K, Frieden M, Westergaard M, Xu Y, Wahren B, Liang Z, Ørum H, Koch T, et al. Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Research [Internet]. 2005;(1):439-447. 访问链接 SCI被引用次数:320.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, et al. Molecular biology: Antisense transcription in the mammalian transcriptome. Science [Internet]. 2005;(5740):1564-1566. 访问链接 SCI被引用次数:946.
Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Research [Internet]. 2005;(5):1671-1677. 访问链接 SCI被引用次数:148.
Chen M, Zhang L, Zhang H-Y, Xiong X, Wang B, Du Q, Lu B, Wahlestedt C, Liang Z. A universal plasmid library encoding all permutations of small interfering RNA. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2005;(7):2356-2361. 访问链接 SCI被引用次数:28.
2004
Xu Y, Linde A, Larsson O, Thormeyer D, Elmen J, Wahlestedt C, Liang Z. Functional comparison of single- and double-stranded siRNAs in mammalian cells. Biochemical and Biophysical Research Communications [Internet]. 2004;(3):680-687. 访问链接 SCI被引用次数:18.
Elmén J, Zhang H-Y, Zuber B, Ljungberg K, Wahren B, Wahlestedt C, Liang Z. Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication. FEBS Letters [Internet]. 2004;(3):285-290. 访问链接 SCI被引用次数:17.
Du Q, Thonberg H, Zhang H-Y, Wahlestedt C, Liang Z. Validating siRNA using a reporter made from synthetic DNA oligonucleotides. Biochemical and Biophysical Research Communications [Internet]. 2004;(1):243-249. 访问链接 SCI被引用次数:30.
Larsson O, Scheele C, Liang Z, Moll J, Karlsson C, Wahlestedt C. Kinetics of Senescence-associated Changes of Gene Expression in an Epithelial, Temperature-sensitive SV40 Large T Antigen Model. Cancer Research [Internet]. 2004;(2):482-489. 访问链接 SCI被引用次数:18.
2003
Thormeyer D, Ammerpohl O, Larsson O, Xu Y, Asinger A, Wahlestedt C, Liang Z. Characterization of lacZ complementation deletions using membrane receptor dimerization. BioTechniques [Internet]. 2003;(2):346-355. 访问链接 SCI被引用次数:5.
Xu Y, Zhang H-Y, Thormeyer D, Larsson O, Du Q, Elmén J, Wahlestedt C, Liang Z. Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs. Biochemical and Biophysical Research Communications [Internet]. 2003;(3):712-717. 访问链接 SCI被引用次数:48.
Zhang H-Y, Mao J, Zhou D, Xu Y, Thonberg H, Liang Z, Wahlestedt C. mRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotides. Nucleic acids research [Internet]. 2003;(14):e72. 访问链接 SCI被引用次数:21.
2002
Larsson O, Thormeyer D, Asinger A, Wihlén B, Wahlestedt C, Liang Z. Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides. Nucleic acids research [Internet]. 2002;(23):e133. 访问链接 SCI被引用次数:1.
2001
Kumar A, Liang Z. Chemical nanoprinting: a novel method for fabricating DNA microchips. Nucleic acids research [Internet]. 2001;(2):E2. 访问链接 SCI被引用次数:13.
Wang R, Liang Z, Hall M, Söderhäll K. A transglutaminase involved in the coagulation system of the freshwater crayfish, Pacifastacus leniusculus. Tissue localisation and cDNA cloning. Fish and Shellfish Immunology [Internet]. 2001;(7):623-637. 访问链接 SCI被引用次数:61.
2000
Kumar A, Larsson O, Parodi D, Liang Z. Silanized nucleic acids: a general platform for DNA immobilization. Nucleic acids research [Internet]. 2000;(14):E71. 访问链接
1997
Liang Z, Sottrup-Jensen L, Aspán A, Hall M, Söderhäll K. Pacifastin, a novel 155-kDa heterodimeric proteinase inhibitor containing a unique transferrin chain. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1997;(13):6682-6687. 访问链接 SCI被引用次数:98.
1995
Liang Z, Söderhäll K. Isolation of cDNA encoding a novel serpin of crayfish hemocytes. Comparative Biochemistry and Physiology -- Part B: Biochemistry and [Internet]. 1995;(2):385-391. 访问链接 SCI被引用次数:23.
1994
Liang Z, Söderhäll K. G2.11 A novel proteinase inhibitor of Serpin-family from crayfish hemocytes: Cloning and functional expression in E. coli. Developmental and Comparative Immunology. 1994;(SUPPL. 1):S126.
Cerenius L, Liang Z, Duvic B, Keyser P, Söderhäll K. G2.13 Recognition of fungi in crustaceans. Developmental and Comparative Immunology. 1994;(SUPPL. 1):S127.

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