科研成果 by Type: 期刊论文

2009
Liu X-X, Rocchi P, Qu F-Q, Zheng S-Q, Liang Z-C, Gleave M, Iovanna J, Peng L. PAMAM dendrimers mediate siRNA delivery to target Hsp27 and produce potent antiproliferative effects on prostate cancer cells. ChemMedChem [Internet]. 2009;(8):1302-1310. 访问链接 SCI被引用次数:76.
Huang H, Qiao R, Zhao D, Zhang T, Li Y, Yi F, Lai F, Hong J, Ding X, Yang Z, et al. Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. Nucleic Acids Research [Internet]. 2009;(22):7560-7569. 访问链接 SCI被引用次数:27.
2008
Hong J, Wei N, Chalk A, Wang J, Song Y, Yi F, Qiao R-P, Sonnhammer ELL, Wahlestedt C, Liang Z, et al. Focusing on RISC assembly in mammalian cells. Biochemical and Biophysical Research Communications [Internet]. 2008;(3):703-708. 访问链接 SCI被引用次数:7.
Dahlgren C, Zhang H-Y, Du Q, Grahn M, Norstedt G, Wahlestedt C, Liang Z. Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Research [Internet]. 2008;(9). 访问链接 SCI被引用次数:34.
2007
Chen M, Du Q, Zhang H-Y, Wang X, Liang Z. High-throughput screening using siRNA (RNAi) libraries. Expert Review of Molecular Diagnostics [Internet]. 2007;(3):281-291. 访问链接 SCI被引用次数:8.
Li Z-S, Qiao R-P, Du Q, Yang Z-J, Zhang L-R, Zhang P-Z, Liang Z-C, Zhang L-H. Studies on aminoisonucleoside modified siRNAs: Stability and silencing activity. Bioconjugate Chemistry [Internet]. 2007;(4):1017-1024. 访问链接 SCI被引用次数:12.
2006
Larsson O, Perlman DM, Fan D, Reilly CS, Peterson M, Dahlgren C, Liang Z, Li S, Polunovsky VA, Wahlestedt C, et al. Apoptosis resistance downstream of eIF4E: Posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Research [Internet]. 2006;(16):4375-4386. 访问链接 SCI被引用次数:43.
Zaslavsky A, Singh LS, Tan H, Ding H, Liang Z, Xu Y. Homo- and hetero-dimerization of LPA/S1P receptors, OGR1 and GPR4. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids [Internet]. 2006;(10):1200-1212. 访问链接 SCI被引用次数:45.
Zhang H-Y, Du Q, Wahlestedt C, Liang Z. RNA interference with chemically modified siRNA. Current Topics in Medicinal Chemistry [Internet]. 2006;(9):893-900. 访问链接 SCI被引用次数:32.
Gao Y, Sun L, Dong J, Xu X, Shu Y, Chen M, Yin L, Liang Z, Jin Q. Rapid identification of small interfering RNA that can effectively inhibit the replication of multiple influenza B virus strains. Antiviral Therapy [Internet]. 2006;(4):431-438. 访问链接 SCI被引用次数:6.
2005
Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. Erratum: A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites (Nucleic Acids Research (2005) vol. 33 (1671-1677)). Nucleic Acids Research. 2005;(11):3698-. SCI被引用次数:1.
Elmén J, Thonberg H, Ljungberg K, Frieden M, Westergaard M, Xu Y, Wahren B, Liang Z, Ørum H, Koch T, et al. Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Research [Internet]. 2005;(1):439-447. 访问链接 SCI被引用次数:320.
Chen M, Zhang L, Zhang H-Y, Xiong X, Wang B, Du Q, Lu B, Wahlestedt C, Liang Z. A universal plasmid library encoding all permutations of small interfering RNA. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2005;(7):2356-2361. 访问链接 SCI被引用次数:28.
Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Research [Internet]. 2005;(5):1671-1677. 访问链接 SCI被引用次数:148.
Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, et al. Molecular biology: Antisense transcription in the mammalian transcriptome. Science [Internet]. 2005;(5740):1564-1566. 访问链接 SCI被引用次数:946.
Liang Z. High-throughput screening using genome-wide siRNA libraries. IDrugs [Internet]. 2005;(11):924-926. 访问链接 SCI被引用次数:3.
2004
Xu Y, Linde A, Larsson O, Thormeyer D, Elmen J, Wahlestedt C, Liang Z. Functional comparison of single- and double-stranded siRNAs in mammalian cells. Biochemical and Biophysical Research Communications [Internet]. 2004;(3):680-687. 访问链接 SCI被引用次数:18.
Du Q, Thonberg H, Zhang H-Y, Wahlestedt C, Liang Z. Validating siRNA using a reporter made from synthetic DNA oligonucleotides. Biochemical and Biophysical Research Communications [Internet]. 2004;(1):243-249. 访问链接 SCI被引用次数:30.
Elmén J, Zhang H-Y, Zuber B, Ljungberg K, Wahren B, Wahlestedt C, Liang Z. Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication. FEBS Letters [Internet]. 2004;(3):285-290. 访问链接 SCI被引用次数:17.
Larsson O, Scheele C, Liang Z, Moll J, Karlsson C, Wahlestedt C. Kinetics of Senescence-associated Changes of Gene Expression in an Epithelial, Temperature-sensitive SV40 Large T Antigen Model. Cancer Research [Internet]. 2004;(2):482-489. 访问链接 SCI被引用次数:18.

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