科研成果 by Type: 期刊论文

2012
Peschansky VJ, Liang Z, Wahlestedt C. RNAi joins the singles club. Molecular Therapy [Internet]. 2012;(11):2010-2011. 访问链接
Wei N, Zhang L, Huang H, Chen Y, Zheng J, Zhou X, Yi F, Du Q, Liang Z. siRNA Has Greatly Elevated Mismatch Tolerance at 3′-UTR Sites. PLoS ONE [Internet]. 2012;(11). 访问链接
2011
Lu Y, Zhang J, Xiong Y, Zhu N, Fan C, Wang S, Liu S, Liang Z, Shen Y, Wang Q, et al. Small interfering RNAs screened from random siRNA library direct neuronal differentiation. Biotechnology Letters [Internet]. 2011;(9):1737-1744. 访问链接
Wei Z, Zhao D, Li X, Wu M, Wang W, Huang H, Wang X, Du Q, Liang Z, Li Z. A laminar flow electroporation system for efficient DNA and siRNA delivery. Analytical Chemistry [Internet]. 2011;(15):5881-5887. 访问链接
Lin D, Huang Y, Jiang Q, Zhang W, Yue X, Guo S, Xiao P, Du Q, Xing J, Deng L, et al. Structural contributions of blocked or grafted poly(2-dimethylaminoethyl methacrylate) on PEGylated polycaprolactone nanoparticles in siRNA delivery. Biomaterials [Internet]. 2011;(33):8730-8742. 访问链接
Zhou J, Neff PC, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, et al. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Molecular Therapy [Internet]. 2011;(12):2228-2238. 访问链接
Huang H, Wei Z, Huang Y, Zhao D, Zheng L, Cai T, Wu M, Wang W, Ding X, Zhou Z, et al. An efficient and high-throughput electroporation microchip applicable for siRNA delivery. Lab on a Chip - Miniaturisation for Chemistry and Biology [Internet]. 2011;(1):163-172. 访问链接
Guo S, Huang Y, Wei T, Zhang W, Wang W, Lin D, Zhang X, Kumar A, Du Q, Xing J, et al. Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly(2-(dimethylamino)ethyl methacrylate)) as an effective gene carrier. Biomaterials [Internet]. 2011;(3):879-889. 访问链接
Huang Y, Hong J, Zheng S, Ding Y, Guo S, Zhang H, Zhang XQ, Du Q, Liang Z. Elimination pathways of systemically delivered siRNA. Molecular Therapy [Internet]. 2011;(2):381-385. 访问链接
Fan C, Xiong Y, Zhu N, Lu Y, Zhang J, Wang S, Liang Z, Shen Y, Chen M. Random small interfering RNA library screen identifies siRNAs that induce human erythroleukemia cell differentiation. Leukemia and Lymphoma [Internet]. 2011;(3):502-514. 访问链接
Guo S, Huang Y, Zhang W, Wang W, Wei T, Lin D, Xing J, Deng L, Du Q, Liang Z, et al. Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery. Biomaterials [Internet]. 2011;(18):4283-4292. 访问链接
2010
Wang X, Yan F, Du Q, Liang Z. SiRNAs as potential drugs. Drug Discovery Today: Technologies [Internet]. 2010;(2):e125-e130. 访问链接
Huang H, Wei N, Xiong Y, Yang F, Fang H, Xie W, Zhou Z, Cheng H, Liang Z, Du Q. Exogenous nucleic acids aggregate in non-P-body cytoplasmic granules when transfected into cultured cells. Frontiers of Biology in China. 2010;(3):272-281.
Xiong J, Yu D, Wei N, Fu H, Cai T, Huang Y, Wu C, Zheng X, Du Q, Lin D, et al. An estrogen receptor α suppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples. FEBS Journal [Internet]. 2010;(7):1684-1694. 访问链接
Xiong J, Du Q, Liang Z. Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein. Oncogene [Internet]. 2010;(35):4980-4988. 访问链接
Guo S, Huang Y, Jiang Q, Sun Y, Deng L, Liang Z, Du Q, Xing J, Zhao Y, Wang PC, et al. Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte. ACS Nano [Internet]. 2010;(9):5505-5511. 访问链接
Xiong X, Lu Y, Zhang L, Wang B, Zhao Y, Wang X-J, Huo X, Shen Y, Liang Z, Chen M. Discovery of novel cell proliferation-enhancing gene by random siRNA library based combinatorial screening. Combinatorial Chemistry and High Throughput Screening [Internet]. 2010;(9):798-806. 访问链接
Hong J, Huang Y, Li J, Yi F, Zheng J, Huang H, Wei N, Shan Y, An M, Zhang H, et al. Comprehensive analysis of sequence-specific stability of siRNA. FASEB Journal [Internet]. 2010;(12):4844-4855. 访问链接
Li J, Liang Z. The consideration of synthetic short interfering RNA for therapeutic use. Basic and Clinical Pharmacology and Toxicology [Internet]. 2010;(1):22-29. 访问链接
2009
Xue Y, Petrovic N, Cao R, Larsson O, Lim S, Chen S, Feldmann HM, Liang Z, Zhu Z, Nedergaard J, et al. Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation. Cell Metabolism [Internet]. 2009;(1):99-109. 访问链接

Pages