科研成果

Magnetic Resonance Imaging (MRI) is widely used in diagnosing anterior cruciate ligament (ACL) injuries due to its ability to provide detailed image data. However, existing deep learning approaches often overlook additional factors beyond the image itself. In this study, we aim to bridge this gap by exploring the relationship between ACL rupture and the bone morphology of the femur and tibia. Leveraging extensive clinical experience, we acknowledge the significance of this morphological data, which is not readily observed manually. To effectively incorporate this vital information, we introduce ACLNet, a novel model that combines the convolutional representation of MRI images with the transformer representation of bone morphological point clouds. This integration significantly enhances ACL injury predictions by leveraging both imaging and geometric data. Our methodology demonstrated an enhancement in diagnostic precision on the in-house dataset compared to image-only methods, elevating the accuracy from 87.59% to 92.57%. This strategy of utilizing implicitly relevant information to enhance performance holds promise for a variety of medical-related tasks.

Hyperspectral imaging plays a critical role in numerous scientific and industrial fields. Conventional hyperspectral imaging systems often struggle with the trade-off between spectral and temporal resolution, particularly in dynamic environments. In ours work, we present an innovative event-based active hyperspectral imaging system designed for real-time performance in dynamic scenes. By integrating a diffraction grating and rotating mirror with an event-based camera, the proposed system captures high-fidelity spectral information at a microsecond temporal resolution, leveraging the event camera's unique capability to detect instantaneous changes in brightness rather than absolute intensity. The proposed system trade-off between conventional frame-based systems by reducing the bandwidth and computational load and mosaic-based system by remaining the original sensor spatial resolution. It records only meaningful changes in brightness, achieving high temporal and spectral resolution with minimal latency and is practical for real-time applications in complex dynamic conditions.

Alquimia v1.0 is a generic interface to geochemical solvers that facilitates development of multiphysics simulators by enabling code coupling, prototyping and benchmarking. The interface enforces the function arguments and their types for setting up, solving, serving up output data and carrying out other common auxiliary tasks while providing a set of structures for data transfer between the multiphysics code driving the simulation and the geochemical solver. Alquimia relies on a single-cell approach that permits operator splitting coupling and parallel computation. We describe the implementation in Alquimia of two widely used open-source codes that perform geochemical calculations: PFLOTRAN and CrunchFlow. We then exemplify its use for the implementation and simulation of reactive transport in porous media by two open-source flow and transport simulators: Amanzi and ParFlow. We also demonstrate its use for the simulation of coupled processes in novel multiphysics applications including the effect of multiphase flow on reaction rates at the pore scale with OpenFOAM, the role of complex biogeochemical processes in land surface models such as the E3SM Land Model (ELM) and the impact of surface–subsurface hydrological interactions on hydrogeochemical export from watersheds with the Advanced Terrestrial Simulator (ATS). These applications make it apparent that the availability of a well-defined yet flexible interface has the potential to improve the software development workflow, freeing up resources to focus on advances in process models and mechanistic understanding of coupled problems.