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陈良怡
北京大学分子医学研究所教授、博士生导师
中关村北一条国家纳米科学中心239室,010-62764959
lychen@ pku.edu.cn
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科研成果 by Type: 期刊论文
2014
Shang W, Lu F, Sun T, Xu J, Li L-L, Wang Y, Wang G, Chen L, Wang X, Cannell MB, et al.
Imaging Ca
2+
nanosparks in heart with a new targeted biosensor
. Circulation Research [Internet]. 2014;(3):412-420.
访问链接
Zong W, Huang X, Zhang C, Yuan T, Zhu L-L, Fan M, Chen L
.
Shadowless-illuminated variable-angle TIRF (siva-TIRF) microscopy for the observation of spatial-temporal dynamics in live cells
. Biomedical Optics Express. 2014;(5):1530-1540.
Liang K, Du W, Lu J, Li F, Yang L, Xue Y, Hille B, Chen L
.
Alterations of the Ca
2+
signaling pathway in pancreatic beta-cells isolated from db/db mice
. Protein & Cell. 2014.
2013
Yang L, Ji W, Xue Y, Chen L
.
Imaging beta-cell mass and function in situ and in vivo
. Journal of Molecular Medicine [Internet]. 2013;(8):929-938.
访问链接
Zhang Y, Gu L, Chang H, Ji W, Chen Y, Zhang M, Yang L, Liu B, Chen L, Xu T
.
Ultrafast, accurate, and robust localization of anisotropic dipoles
. Protein and Cell [Internet]. 2013;(8):598-606.
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2012
Shen JZ, Ma LN, Han Y, Liu JX, Yang WQ, Chen L, Liu Y, Hu Y, Jin MW
.
Pentamethylquercetin generates beneficial effects in monosodium glutamate-induced obese mice and C2C12 myotubes by activating AMP-activated protein kinase
. Diabetologia [Internet]. 2012;(6):1836-1846.
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Koh D-S, Cho J-H, Chen L
.
Paracrine interactions within islets of Langerhans
. Journal of Molecular Neuroscience [Internet]. 2012;(2):429-440.
访问链接
Wen D, Xue Y, Liang K, Yuan T, Lu J, Zhao W, Xu T, Chen L
.
Bulk-like endocytosis plays an important role in the recycling of insulin granules in pancreatic beta cells
. Protein and Cell [Internet]. 2012;(8):618-626.
访问链接
Dickson EJ, Duman JG, Moody MW, Chen L, Hille B
.
Orai-STIM-mediated Ca
2+
release from secretory granules revealed by a targeted Ca
2+
and pH probe
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2012;(51):E3539-E3548.
访问链接
2011
Li Z, Liu L, Deng Y, Ji W, Du W, Xu P, Chen L, Xu T
.
Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits
. Cell Research [Internet]. 2011;(2):305-315.
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Koh D-S, Chen L, Ufret-Vincenty CA, Jung S-R
.
A fast solution switching system with temperature control for single cell measurements
. Journal of Neuroscience Methods [Internet]. 2011;(1):35-42.
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Liu L, Zhang M, Xia Z, Xu P, Chen L, Xu T
.
Caenorhabditis elegans ciliary protein NPHP-8, the homologue of human RPGRIP1L, is required for ciliogenesis and chemosensation
. Biochemical and Biophysical Research Communications [Internet]. 2011;(3):626-631.
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Liang K, Du W, Zhu W, Liu S, Cui Y, Sun H, Luo B, Xue Y, Yang L, Chen L, et al.
Contribution of different mechanisms to pancreatic beta-cell hyper-secretion in non-obese diabetic (NOD) mice during pre-diabetes
. Journal of Biological Chemistry [Internet]. 2011;(45):39537-39545.
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2010
Zhang Y-D, Chen L-Y, Xu T
.
Application of improved wavelet transform in biological particle detection
. Progress in Biochemistry and Biophysics. 2010;(10):1144-1150.
Cho J-H, Chen L, Kim M-H, Chow RH, Hille B, Koh D-S
.
Characteristics and functions of α-amino-3-hydroxy-5-methyl-4- isoxazolepropionate receptors expressed in mouse pancreatic α-cells
. Endocrinology [Internet]. 2010;(4):1541-1550.
访问链接
Yang L, Zhao L, Gan Z, He Z, Xu J, Gao X, Wang X, Han W, Chen L, Xu T, et al.
Deficiency in RNA editing enzyme ADAR2 impairs regulated exocytosis
. FASEB Journal [Internet]. 2010;(10):3720-3732.
访问链接
Song X, Su W, Chen L, Ji JJ
.
Functional expression of large-conductance Ca
2+
-activated potassium channels in lateral globus pallidus neurons
. Neuroscience [Internet]. 2010;(4):1548-1556.
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2009
Lü Z-J, Lu J-Z, Wu Y-Q, Chen L-Y
.
Introduction to theories of several super-resolution fluorescence microscopy methods and recent advance in the field
. Progress in Biochemistry and Biophysics. 2009;(12):1626-1634.
Gao S, Fan Y, Chen L, Lu J, Xu T, Xu P
.
Mechanism of different spatial distributions of Caenorhabditis elegans and human STIM1 at resting state
. Cell Calcium [Internet]. 2009;(1):77-88.
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2008
Jiang L, Fan J, Bai L, Wang Y, Chen Y, Yang L, Chen L, Xu T
.
Direct quantification of fusion rate reveals a distal role for AS160 in insulin-stimulated fusion of GLUT4 storage vesicles
. Journal of Biological Chemistry [Internet]. 2008;(13):8508-8516.
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最新科研成果
Alterations of the Ca
2+
signaling pathway in pancreatic beta-cells isolated from db/db mice
Imaging Ca
2+
nanosparks in heart with a new targeted biosensor
Shadowless-illuminated variable-angle TIRF (siva-TIRF) microscopy for the observation of spatial-temporal dynamics in live cells
更多成果