科研成果

2014
Liang K, Du W, Lu J, Li F, Yang L, Xue Y, Hille B, Chen L. Alterations of the Ca2+ signaling pathway in pancreatic beta-cells isolated from db/db mice. Protein & Cell. 2014. SCI被引用次数:4.
Shang W, Lu F, Sun T, Xu J, Li L-L, Wang Y, Wang G, Chen L, Wang X, Cannell MB, et al. Imaging Ca2+ nanosparks in heart with a new targeted biosensor. Circulation Research [Internet]. 2014;(3):412-420. 访问链接 SCI被引用次数:30.
Zong W, Huang X, Zhang C, Yuan T, Zhu L-L, Fan M, Chen L. Shadowless-illuminated variable-angle TIRF (siva-TIRF) microscopy for the observation of spatial-temporal dynamics in live cells. Biomedical Optics Express. 2014;(5):1530-1540. SCI被引用次数:5.
Zong W, Chen X, Zhao J, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L. Two-photon three-axis digital scanned light-sheet microscopy (2P3A-DSLM). Optics InfoBase Conference Papers. 2014.
2013
Yang L, Ji W, Xue Y, Chen L. Imaging beta-cell mass and function in situ and in vivo. Journal of Molecular Medicine [Internet]. 2013;(8):929-938. 访问链接 SCI被引用次数:8.
Zhang Y, Gu L, Chang H, Ji W, Chen Y, Zhang M, Yang L, Liu B, Chen L, Xu T. Ultrafast, accurate, and robust localization of anisotropic dipoles. Protein and Cell [Internet]. 2013;(8):598-606. 访问链接 SCI被引用次数:5.
2012
Wen D, Xue Y, Liang K, Yuan T, Lu J, Zhao W, Xu T, Chen L. Bulk-like endocytosis plays an important role in the recycling of insulin granules in pancreatic beta cells. Protein and Cell [Internet]. 2012;(8):618-626. 访问链接 SCI被引用次数:2.
Dickson EJ, Duman JG, Moody MW, Chen L, Hille B. Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2012;(51):E3539-E3548. 访问链接 SCI被引用次数:23.
Koh D-S, Cho J-H, Chen L. Paracrine interactions within islets of Langerhans. Journal of Molecular Neuroscience [Internet]. 2012;(2):429-440. 访问链接 SCI被引用次数:27.
Shen JZ, Ma LN, Han Y, Liu JX, Yang WQ, Chen L, Liu Y, Hu Y, Jin MW. Pentamethylquercetin generates beneficial effects in monosodium glutamate-induced obese mice and C2C12 myotubes by activating AMP-activated protein kinase. Diabetologia [Internet]. 2012;(6):1836-1846. 访问链接 SCI被引用次数:19.
2011
Liu L, Zhang M, Xia Z, Xu P, Chen L, Xu T. Caenorhabditis elegans ciliary protein NPHP-8, the homologue of human RPGRIP1L, is required for ciliogenesis and chemosensation. Biochemical and Biophysical Research Communications [Internet]. 2011;(3):626-631. 访问链接 SCI被引用次数:9.
Liang K, Du W, Zhu W, Liu S, Cui Y, Sun H, Luo B, Xue Y, Yang L, Chen L, et al. Contribution of different mechanisms to pancreatic beta-cell hyper-secretion in non-obese diabetic (NOD) mice during pre-diabetes. Journal of Biological Chemistry [Internet]. 2011;(45):39537-39545. 访问链接 SCI被引用次数:9.
Koh D-S, Chen L, Ufret-Vincenty CA, Jung S-R. A fast solution switching system with temperature control for single cell measurements. Journal of Neuroscience Methods [Internet]. 2011;(1):35-42. 访问链接 SCI被引用次数:1.
Li Z, Liu L, Deng Y, Ji W, Du W, Xu P, Chen L, Xu T. Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits. Cell Research [Internet]. 2011;(2):305-315. 访问链接 SCI被引用次数:73.
2010
Zhang Y-D, Chen L-Y, Xu T. Application of improved wavelet transform in biological particle detection. Progress in Biochemistry and Biophysics. 2010;(10):1144-1150. SCI被引用次数:3.
Cho J-H, Chen L, Kim M-H, Chow RH, Hille B, Koh D-S. Characteristics and functions of α-amino-3-hydroxy-5-methyl-4- isoxazolepropionate receptors expressed in mouse pancreatic α-cells. Endocrinology [Internet]. 2010;(4):1541-1550. 访问链接 SCI被引用次数:15.
Yang L, Zhao L, Gan Z, He Z, Xu J, Gao X, Wang X, Han W, Chen L, Xu T, et al. Deficiency in RNA editing enzyme ADAR2 impairs regulated exocytosis. FASEB Journal [Internet]. 2010;(10):3720-3732. 访问链接 SCI被引用次数:15.
Song X, Su W, Chen L, Ji JJ. Functional expression of large-conductance Ca2+-activated potassium channels in lateral globus pallidus neurons. Neuroscience [Internet]. 2010;(4):1548-1556. 访问链接 SCI被引用次数:8.
2009
Lü Z-J, Lu J-Z, Wu Y-Q, Chen L-Y. Introduction to theories of several super-resolution fluorescence microscopy methods and recent advance in the field. Progress in Biochemistry and Biophysics. 2009;(12):1626-1634. SCI被引用次数:2.
Gao S, Fan Y, Chen L, Lu J, Xu T, Xu P. Mechanism of different spatial distributions of Caenorhabditis elegans and human STIM1 at resting state. Cell Calcium [Internet]. 2009;(1):77-88. 访问链接 SCI被引用次数:8.

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