摘要:

Enantiopure trans-3-trifluoromethylsulfonylamino-4-silyloxypyrrolidines efficiently catalyse the asymmetric alpha-aminoxylation of aldehydes. At 1% catalyst loading (solvent-free conditions) or at 2% catalyst loading (acetonitrile solution) aldehydes are completely converted in short reaction times leading to alpha-aminoxylation products with very high (96-99%) enantioselectivity.

附注:

971PPTimes Cited:3Cited References Count:36