Improvement of the AlGaN/GaN high-electron mobility transistor's (HEMT's) OFF-state breakdown voltage is achieved by implanting (19)F(+) ions at an energy of 50 keV and dose of 1 x 10(12) cm(-2) under the gate region using BF(3) as the source. The charge state of the implanted fluorine ions changes from positive to negative in the AlGaN/GaN structure because of fluorine's strong electronegativity. The negative-charged fluorine ions at the back side of the two-dimensional electron gas can raise the energy barrier of the GaN buffer layer under the channel, effectively blocking the current injected from the source to the high-field region of the GaN channel when the HEMT is biased at OFF-state. The source-injected electrons, if not blocked, could flow to the high-field region and initiate a premature three-terminal OFF-state breakdown in a conventional AlGaN/GaN HEMT. A 38% improvement of the three-terminal OFF-state breakdown voltage and 40% improvement of the power figure-of-merit V(BD-off)(2)/R(on) are achieved in the enhanced back barrier HEMT.
China operated an urbanization policy by which counties could be given city status between 1983 and 1997. The policy had substantial impacts on the new administrative entities, including more discretionary power and fiscal independence. Such "county-to-city upgrading" provided the central government with an instrument to reward localities. Using a large dataset covering all counties during 1993-1997. I show that upgrading is not an automatic procedure that endorses the high urbanization levels in existing counties. Although official guidelines for upgrading counties to cities were published, these requirements were largely ignored in practice. Instead, economic growth rate was the key factor in determining which counties obtained city status. This paper interprets the creation of county-level cities through upgrading as part of the incentive structure of Chinese local officials. The importance of both fiscal and political incentives facing the local government in promoting economic growth is highlighted.
At a rural site in the central Pearl River Delta (PRD) region in south China, fine particle (PM2.5) samples were collected during fall-winter 2007 to measure biogenic secondary organic aerosol (SOA) tracers, including isoprene SOA tracers (3-methyl-2,3,4-trihydroxy-1-butene, 2-methylglyceric acid, 2-methylthreitol and 2-methylerythritol), α-pinene SOA tracers (cis-pinonic acid, pinic acid, 3-methyl-1,2,3-butanetricarboxylic acid, 3-hydroxyglutaric acid and 3-hydroxy-4,4-dimethylglutaric acid) and a sesquiterpene SOA tracer (β-caryophyllinic acid). The isoprene-, α-pinene- and sesquiterpene-SOA tracers averaged 30.8±15.9, 6.61±4.39, and 0.54±0.56ngm−3, respectively; and 2-methyltetrols (sum of 2-methylthreitol and 2-methylerythritol, 27.6±15.1ngm−3) and cis-pinonic acid (3.60±3.76ngm−3) were the dominant isoprene- and α-pinene-SOA tracers, respectively. 2-Methyltetrols exhibited significantly positive correlations (p<0.05) with ambient temperature, probably resulting from the enhanced isoprene emission strength and tracer formation rate under higher temperature. The significantly positive correlation (p<0.05) between 2-methyltetrols and the estimated aerosol acidity with a slope of 59.4±13.4ngm−3 per μmol [H+] m−3 reflected the enhancement of isoprene SOA formation by aerosol acidity, and acid-catalyzed heterogeneous reaction was probably the major formation pathway for 2-methyltetrols in the PRD region. 2-Methylglyceric acid showed poor correlations with both temperature and aerosol acidity. The α-pinene SOA tracers showed poor correlations with temperature, probably due to the counteraction between temperature effects on the precursor emission/tracer formation and gas/particle partitioning. Among the α-pinene SOA tracers, only cis-pinonic acid and pinic acid exhibited significant correlations with aerosol acidity with slopes of −11.7±3.7 and −2.2±0.8ngm−3 per μmol [H+] m−3, respectively. The negative correlations observed for α-pinene SOA tracers might result from their transfer from particle to gas phase with the increase of aerosol acidity. The ratio of cis-pinonic acid plus pinic acid to 3-methyl-1,2,3-butanetricarboxylic acid (MBTCA) ranged from 0.28 to 28.9 with a mean of 7.19, indicating the relatively fresh α-pinene SOA tracers during our campaign.
AIM: Angiotensin-converting enzyme inhibitors are widely used antihypertensive drugs with individual response variation. We studied whether interactions of AGT, AGTR1 and ACE2 gene polymorphisms affect this response. MATERIALS & METHODS: Our study is based on a 3-year field trial with 1831 hypertensive patients prescribed benazepril. Generalized multifactor dimensionality reduction was used to explore interaction models and logistic regressions were used to confirm them. RESULTS: A two-locus model involving the AGT and ACE2 genes was found in males, the sensitive genotypes showed an odds ratio (OR) of 1.9 (95% CI: 1.3-2.8) when compared with nonsensitive genotypes. Two AGT-AGTR1 models were found in females, with an OR of 3.5 (95% CI: 2.0-5.9) and 3.1 (95% CI: 1.8-5.3). CONCLUSION: Gender-specific gene-gene interactions of the AGT, AGTR1 and ACE2 genes were associated with individual variation of response to benazepril. Further studies are needed to confirm this finding.
n intercomparison of organic carbon (OC) and elemental carbon (EC) measurements was conducted based on ambient aerosol samples collected during four seasons in Beijing, China. Dependence of OC and EC values on the temperature protocol and the charring correction method is presented and influences of aerosol composition are investigated. EC was found to decrease with the peak inert mode temperature (Tpeak) such that EC determined by the IMPROVE (the Interagency Monitoring of Protected Visual Environments)-A protocol (Tpeak was 580 °C) was 2.85 ± 1.31 and 3.83 ± 2.58 times that measured by an alternative protocol with a Tpeak of 850 °C when using the transmittance and reflectance correction, respectively. It was also found that reflectance correction tends to classify more carbon as EC compared with transmittance; results from the IMPROVE-A protocol showed that the ratio of EC defined by reflectance correction (ECR) to that based on transmittance (ECT) averaged 1.50 ± 0.42. Moreover, it was demonstrated that emissions from biomass burning would increase the discrepancy between EC values determined by different temperature protocols. On the other hand, the discrepancy between ECR and ECT was strongly associated with secondary organic aerosol (SOA) which was shown to be an important source of the organics that pyrolyze during the inert mode of thermal–optical analysis.