科研成果 by Type: 期刊论文

2014
Deng Y, Wang CC, Choy KW, Du Q, Chen J, Wang Q, Li L, Chung TKH, Tang T. Therapeutic potentials of gene silencing by RNA interference: Principles, challenges, and new strategies. Gene [Internet]. 2014;(2):217-227. 访问链接 SCI被引用次数:86.
Huang W, Zhao M, Wei N, Wang X, Cao H, Du Q, Liang Z. Site-specific RNase A activity was dramatically reduced in serum from multiple types of cancer patients. PLoS ONE. 2014;(5). SCI被引用次数:4.
2013
Zheng J, Zhang L, Zhang J, Wang X, Ye K, Xi Z, Du Q, Liang Z. Single modification at position 14 of siRNA strand abolishes its gene-silencing activity by decreasing both RISC loading and target degradation. FASEB Journal [Internet]. 2013;(10):4017-4026. 访问链接 SCI被引用次数:8.
Yang F, Yi F, Han X, Du Q, Liang Z. MALAT-1 interacts with hnRNP C in cell cycle regulation. FEBS Letters [Internet]. 2013;(19):3175-3181. 访问链接 SCI被引用次数:36.
Yi F, Li D, Ma W, Du Q. GLP-1 biology and GLP-1 based antidiabetic therapy. Journal of Chinese Pharmaceutical Sciences. 2013;(1):7-27.
Yi F, Yang F, Liu X, Chen H, Ji T, Jiang L, Wang X, Yang Z, Zhang L-H, Ding X, et al. RNA-seq identified a super-long intergenic transcript functioning in adipogenesis. RNA Biology. 2013;(6):983-994. SCI被引用次数:11.
Wang X, Huang Y, Liu Y, Chen Y, Jin H, Zheng Y, Du Q, Yang Z, Zhang L. Synthesis and biological evaluation of peptide-siRNA conjugates with phosphodiester unit as linker. Science China Chemistry. 2013;(11):1542-1549. SCI被引用次数:4.
Cheng Q, Huang Y, Zheng H, Wei T, Zheng S, Huo S, Wang X, Du Q, Zhang X, Zhang H-Y, et al. The effect of guanidinylation of PEGylated poly(2-aminoethyl methacrylate) on the systemic delivery of siRNA. Biomaterials [Internet]. 2013;(12):3120-3131. 访问链接 SCI被引用次数:25.
Yi F, Yang F, Liu X, Chen H, Ji T, Jiang L, Wang X, Yang Z, Zhang L-H, Ding X, et al. RNA-seq identified a super-long intergenic transcript functioning in adipogenesis. RNA biology [Internet]. 2013;(6):991-1001. 访问链接 SCI被引用次数:11.
2012
Yang F, Yi F, Zheng Z, Ling Z, Ding J, Guo J, Mao W, Wang X, Wang X, Ding X, et al. Characterization of a carcinogenesis-associated long non-coding RNA. RNA Biology [Internet]. 2012;(1):110-116. 访问链接 SCI被引用次数:15.
Ding X, Ding J, Ning J, Yi F, Chen J, Zhao D, Zheng J, Liang Z, Hu Z, Du Q. Circulating microRNA-122 as a potential biomarker for liver injury. Molecular Medicine Reports [Internet]. 2012;(6):1428-1432. 访问链接 SCI被引用次数:35.
Huang Y, Lin D, Jiang Q, Zhang W, Guo S, Xiao P, Zheng S, Wang X, Chen H, Zhang H-Y, et al. Binary and ternary complexes based on polycaprolactone-graft-poly (N, N-dimethylaminoethyl methacrylate) for targeted siRNA delivery. Biomaterials [Internet]. 2012;(18):4653-4664. 访问链接 SCI被引用次数:21.
Zhang J, Zheng J, Lu C, Du Q, Liang Z, Xi Z. Modification of the siRNA Passenger Strand by 5-Nitroindole Dramatically Reduces its Off-Target Effects. ChemBioChem [Internet]. 2012;(13):1940-1945. 访问链接 SCI被引用次数:8.
Wei N, Zhang L, Huang H, Chen Y, Zheng J, Zhou X, Yi F, Du Q, Liang Z. siRNA Has Greatly Elevated Mismatch Tolerance at 3′-UTR Sites. PLoS ONE [Internet]. 2012;(11). 访问链接 SCI被引用次数:6.
2011
Wei Z, Zhao D, Li X, Wu M, Wang W, Huang H, Wang X, Du Q, Liang Z, Li Z. A laminar flow electroporation system for efficient DNA and siRNA delivery. Analytical Chemistry [Internet]. 2011;(15):5881-5887. 访问链接 SCI被引用次数:21.
Lin D, Huang Y, Jiang Q, Zhang W, Yue X, Guo S, Xiao P, Du Q, Xing J, Deng L, et al. Structural contributions of blocked or grafted poly(2-dimethylaminoethyl methacrylate) on PEGylated polycaprolactone nanoparticles in siRNA delivery. Biomaterials [Internet]. 2011;(33):8730-8742. 访问链接 SCI被引用次数:36.
Zhou J, Neff PC, Liu X, Zhang J, Li H, Smith DD, Swiderski P, Aboellail T, Huang Y, Du Q, et al. Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice. Molecular Therapy [Internet]. 2011;(12):2228-2238. 访问链接 SCI被引用次数:83.
Huang H, Wei Z, Huang Y, Zhao D, Zheng L, Cai T, Wu M, Wang W, Ding X, Zhou Z, et al. An efficient and high-throughput electroporation microchip applicable for siRNA delivery. Lab on a Chip - Miniaturisation for Chemistry and Biology [Internet]. 2011;(1):163-172. 访问链接 SCI被引用次数:28.
Guo S, Huang Y, Wei T, Zhang W, Wang W, Lin D, Zhang X, Kumar A, Du Q, Xing J, et al. Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly(2-(dimethylamino)ethyl methacrylate)) as an effective gene carrier. Biomaterials [Internet]. 2011;(3):879-889. 访问链接 SCI被引用次数:74.
Huang Y, Hong J, Zheng S, Ding Y, Guo S, Zhang H, Zhang XQ, Du Q, Liang Z. Elimination pathways of systemically delivered siRNA. Molecular Therapy [Internet]. 2011;(2):381-385. 访问链接 SCI被引用次数:43.

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