科研成果

2011
Sun Z, Zhang J, Zhang J, Chen C, Du Q, Chang L, Cao C, Zheng M, Garcia-Barrio MT, Chen YE, et al. Rad GTPase induces cardiomyocyte apoptosis through the activation of p38 mitogen-activated protein kinase. Biochemical and Biophysical Research Communications [Internet]. 2011;(1):52-57. 访问链接 SCI被引用次数:7.
Guo S, Huang Y, Zhang W, Wang W, Wei T, Lin D, Xing J, Deng L, Du Q, Liang Z, et al. Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery. Biomaterials [Internet]. 2011;(18):4283-4292. 访问链接 SCI被引用次数:56.
Li Z, Wei Z, Li X, Du Q, Liang Z. Efficient and high-throughput electroporation chips. 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11. 2011:1825-1828.
2010
Huang H, Wei N, Xiong Y, Yang F, Fang H, Xie W, Zhou Z, Cheng H, Liang Z, Du Q. Exogenous nucleic acids aggregate in non-P-body cytoplasmic granules when transfected into cultured cells. Frontiers of Biology in China. 2010;(3):272-281.
Wang X, Yan F, Du Q, Liang Z. SiRNAs as potential drugs. Drug Discovery Today: Technologies [Internet]. 2010;(2):e125-e130. 访问链接
Hong J, Huang Y, Li J, Yi F, Zheng J, Huang H, Wei N, Shan Y, An M, Zhang H, et al. Comprehensive analysis of sequence-specific stability of siRNA. FASEB Journal [Internet]. 2010;(12):4844-4855. 访问链接 SCI被引用次数:28.
Guo S, Huang Y, Jiang Q, Sun Y, Deng L, Liang Z, Du Q, Xing J, Zhao Y, Wang PC, et al. Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte. ACS Nano [Internet]. 2010;(9):5505-5511. 访问链接 SCI被引用次数:195.
Xiong J, Yu D, Wei N, Fu H, Cai T, Huang Y, Wu C, Zheng X, Du Q, Lin D, et al. An estrogen receptor α suppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples. FEBS Journal [Internet]. 2010;(7):1684-1694. 访问链接 SCI被引用次数:98.
Li C-Y, Zhang Y, Wang Z, Zhang Y, Cao C, Zhang P-W, Lu S-J, Li X-M, Yu Q, Zheng X, et al. A human-specific de novo protein-coding gene associated with human brain functions. PLoS Computational Biology [Internet]. 2010;(3). 访问链接 SCI被引用次数:52.
Xiong J, Du Q, Liang Z. Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein. Oncogene [Internet]. 2010;(35):4980-4988. 访问链接 SCI被引用次数:75.
2009
Huang H, Qiao R, Zhao D, Zhang T, Li Y, Yi F, Lai F, Hong J, Ding X, Yang Z, et al. Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. Nucleic Acids Research [Internet]. 2009;(22):7560-7569. 访问链接 SCI被引用次数:28.
2008
Dahlgren C, Zhang H-Y, Du Q, Grahn M, Norstedt G, Wahlestedt C, Liang Z. Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Research [Internet]. 2008;(9). 访问链接 SCI被引用次数:34.
Hong J, Wei N, Chalk A, Wang J, Song Y, Yi F, Qiao R-P, Sonnhammer ELL, Wahlestedt C, Liang Z, et al. Focusing on RISC assembly in mammalian cells. Biochemical and Biophysical Research Communications [Internet]. 2008;(3):703-708. 访问链接 SCI被引用次数:7.
2007
Chen M, Du Q, Zhang H-Y, Wang X, Liang Z. High-throughput screening using siRNA (RNAi) libraries. Expert Review of Molecular Diagnostics [Internet]. 2007;(3):281-291. 访问链接 SCI被引用次数:8.
Li Z-S, Qiao R-P, Du Q, Yang Z-J, Zhang L-R, Zhang P-Z, Liang Z-C, Zhang L-H. Studies on aminoisonucleoside modified siRNAs: Stability and silencing activity. Bioconjugate Chemistry [Internet]. 2007;(4):1017-1024. 访问链接 SCI被引用次数:12.
2006
Zhang H-Y, Du Q, Wahlestedt C, Liang Z. RNA interference with chemically modified siRNA. Current Topics in Medicinal Chemistry [Internet]. 2006;(9):893-900. 访问链接 SCI被引用次数:33.
2005
Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. Erratum: A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites (Nucleic Acids Research (2005) vol. 33 (1671-1677)). Nucleic Acids Research. 2005;(11):3698-. SCI被引用次数:1.
Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Research [Internet]. 2005;(5):1671-1677. 访问链接 SCI被引用次数:148.
Chen M, Zhang L, Zhang H-Y, Xiong X, Wang B, Du Q, Lu B, Wahlestedt C, Liang Z. A universal plasmid library encoding all permutations of small interfering RNA. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2005;(7):2356-2361. 访问链接 SCI被引用次数:28.
2004
Benito M, Parker J, Du Q, Wu J, Xiang D, Perou CM, Marron JS. Adjustment of systematic microarray data biases. Bioinformatics [Internet]. 2004;(1):105-114. 访问链接 SCI被引用次数:217.

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