科研成果

2017
Wu ZJ, Zheng J, Wang Y, Shang DJ, Du ZF, Zhang YH, Hu M. Chemical and physical properties of biomass burning aerosols and their CCN activity: A case study in Beijing, China. Science of the Total Environment. 2017;579:1260-1268.Abstract
Biomass burning emits large amounts of both trace gases and particles into the atmosphere. It plays a profound role in regional air quality and climate change. In the present study, an intensive campaign was carried out at an urban site in Beijing, China, in June 2014, which covered the winter wheat harvest season over the North China Plain (NCP). Meanwhile, two evident biomass-burning events were observed. A clear burst in ultrafine particles (below 100 nm in diameter, PM1) and subsequent particle growth took place during the events. With the growth of the ultrafine particles, the organic fraction of PM1 increased significantly. The ratio of oxygen to carbon (O:C), which had an average value of 0.23 +/- 0.04, did not show an obvious enhancement, indicating that a significant chemical aging process of the biomass-burning aerosols was not observed during the course of events. This finding might have been due to the fact that the biomass-burning events occurred in the late afternoon and grewduring the nighttime, which is associated with a low atmospheric oxidation capacity. On average, organics and black carbon (BC) were dominant in the biomass-burning aerosols, accounting for 60 +/- 10% and 18 +/- 3% of PM1. The high organic and BC fractions led to a significant suppression of particle hygroscopicity. Comparisons among hygroscopicity tandem differential mobility analyzer (HTDMA)-derived, cloud condensation nuclei counter (CCNc)-derived, and aerosol mass spectrometer-based hygroscopicity parameter (kappa) values were consistent. The mean. values of biomass-burning aerosols derived from both HTDMA and CCNc measurements were approximately 0.1, regardless of the particle size, indicating that the biomass-burning aerosols were less active. The burst in particle count during the biomass-burning events resulted in an increased number of cloud condensation nuclei (CCN) at supersaturation (SS)= 0.2-0.8%. (C) 2016 Elsevier B.V. All rights reserved.
Shi J. Chern-Simons Theory and Dynamics of Composite Fermions. preprint. 2017:arXiv:1704.07712.Abstract
We propose a Chern-Simons field theoretical description of the fractional quantum Hall effect in 1+4 dimensions. It suggests that composite fermions reside on a momentum manifold with a nonzero Chern number. Based on derivations from microscopic wave functions, we further show that the momentum manifold has a uniformly distributed Berry curvature. As a result, composite fermions do not follow the ordinary Newtonian dynamics as commonly believed, but the more general symplectic one. For a Landau level with the particle-hole symmetry, the theory correctly predicts its Hall conductance at half-filling as well as the symmetry between an electron filling fraction and its hole counterpart.
Jin Y, Andersson H, Zhang S. China’s Cap on Coal and the Efficiency of Local Interventions: A Benefit-Cost Analysis of Phasing out Coal in Power Plants and in Households in Beijing. Journal of Benefit-Cost Analysis. 2017;8:147–186.
唐迅, 张杜丹, 何柳, 曹洋, 王晋伟, 李娜, 黄少平, 窦会东, 高培, 胡永华. China-PAR模型在北方农村人群中预测动脉粥样硬化性心血管疾病发病风险的应用. 北京大学学报(医学版)北京大学学报(医学版). 2017;49:439-445.Abstract
目的:在中国北方农村人群的前瞻性队列中,独立验证并比较动脉粥样硬化性心血管疾病(atherosclerotic cardiovascular disease,ASCVD)5年发病风险预测模型的准确性,对模型的实际应用进行评价并提供证据。方法:研究对象为2010年6至8月参加基线调查并随访至2017年1月的6 489名基线调查时未患ASCVD的40~79岁北京房山农村人群,分别采用美国心脏病学会/美国心脏协会指南最新发布的汇总队列公式(pooled cohort equations,PCE)和中国动脉粥样硬化性心血管疾病风险预测研究(prediction for ASCVD risk in China,China-PAR)的模型计算预测的5年发病风险。通过Kaplan-Meier方法调整获得5年实际观察到的新发ASCVD事件(包括急性心肌梗死、冠心病死亡以及致死和非致死性脑卒中)的发病率,并计算预测风险/实际发病率的比值以评价验证队列中是否存在风险高估或低估。研究人群按照ASCVD预测风险分为4个类别(<5.0%、5.0%~7.4%、7.5%~9.9%以及≥10.0%)进行比较。采用区分度C统计量、校准度卡方值以及校准图评估模型的预测准确性。结果:在本验证队列6 489名研究对象平均5.82年的随访时间内,共出现新发ASCVD事件955例。China-PAR模型高估了ASCVD的5年发病风险,再校准后对男性和女性的发病风险分别高估了22.2%和33.1%;而PCE模型的高估程度更严重,再校准后男性和女性分别高估了67.3%和53.1%。China-PAR和PCE模型的区分度接近,C统计量及其95%可信区间在男性中分别为0.696(0.669~0.723)和0.702(0.675~0.730),在女性中分别为0.709(0.690~0.728)和0.714(0.695~0.733)。China-PAR模型的校准度卡方值在男性和女性中分别为17.2和54.2,但PCE模型的校准度较差(男性和女性分别为192.0和181.2)。另外,只有China-PAR模型的校准图显示其预测风险与实际发病率的一致性较好,特别是在男性人群。结论:作为国内开展ASCVD风险评估和一级预防的工具,China-PAR模型对于中国北方农村人群ASCVD 5年发病风险的预测优于PCE模型,特别是在男性中更加准确。
Jin Y, Andersson H, Zhang S. China's Cap on Coal and the Efficiency of Local Interventions: A Benefit-Cost Analysis of Phasing out Coal in Power Plants and in Households in Beijing. Journal of Benefit-Cost Analysis. 2017;8:147–186.
Guo C, Wen X, Li N, Wang Z, Chen G, Zheng X. Is Cigarette and Alcohol Use Associated With High-Risk Sexual Behaviors Among Youth in China?. J Sex MedJ Sex MedJ Sex Med. 2017;14:659-665.
Liu D, Shi J. Circular Phonon Dichroism in Weyl Semimetals. Phys. Rev. Lett. 2017;119:075301.Abstract
We derive the phonon dynamics of magnetic metals in the presence of strong spin-orbit coupling. We show that both a dissipationless viscosity and a dissipative viscosity arise in the dynamics. While the dissipationless viscosity splits the dispersion of left-handed and right-handed circularly polarized phonons, the dissipative viscosity damps them differently, inducing circular phonon dichroism. The effect offers a new degree of manipulation of phonons, i.e., the control of the phonon polarization. We investigate the effect in Weyl semimetals. We find that there exists strong circular phonon dichroism in Weyl semimetals breaking both the time-reversal and the inversion symmetry, making them potential materials for realizing the acoustic circular polarizer.
A class of vertex-edge-growth small-world network models having scale-free, self-similar and hierarchical characters. Physica A: Statistical Mechanics and its Applications [Internet]. 2017. 访问链接
Lin Y, Liu HB, Dale JE, Di Li, Zhongshi Wang, Busquet G, Zhang Z-Y, Ginsburg A, Galván-Madrid R, Kovács A, Koch E, et al. Cloud Structure of Three Galactic Infrared Dark Star-forming Regions from Combining Ground- and Space-based Bolometric Observations. \apj. 2017;840:22.
Wang X, Congdon N, Ma Y, Hu M, Zhou Y, Liao W, Jin L, Xiao B, Wu X, Ni M, et al. Cluster-randomized controlled trial of the effects of free glasses on purchase of children's glasses in China: The PRICE (Potentiating Rural Investment in Children's Eyecare) study. PLoS One. 2017;12:e0187808.Abstract
Background Offering free glasses can be important to increase children’s wear. We sought to assess whether “Upgrade glasses” could avoid reduced glasses sales when offering free glasses to children in China. Methods In this cluster-randomized, controlled trial, children with uncorrected visual acuity (VA)< = 6/12 in either eye correctable to >6/12 in both eyes at 138 randomly-selected primary schools in 9 counties in Guangdong and Yunnan provinces, China, were randomized by school to one of four groups: glasses prescription only (Control); Free Glasses; Free Glasses + offer of $15 Upgrade Glasses; Free Glasses + offer of $30 Upgrade Glasses. Spectacle purchase (main outcome) was assessed 6 months after randomization. Results Among 10,234 children screened, 882 (8.62%, mean age 10.6 years, 45.5% boys) were eligible and randomized: 257 (29.1%) at 37 schools to Control; 253 (28.7%) at 32 schools to Free Glasses; 187 (21.2%) at 31 schools to Free Glasses + $15 Upgrade; and 185 (21.0%) at 27 schools to Free Glasses +$30 Upgrade. Baseline ownership among these children needing glasses was 11.8% (104/882), and 867 (98.3%) children completed follow-up. Glasses purchase was significantly less likely when free glasses were given: Control: 59/250 = 23.6%; Free glasses: 32/252 = 12.7%, P = 0.010. Offering Upgrade Glasses eliminated this difference: Free + $15 Upgrade: 39/183 = 21.3%, multiple regression relative risk (RR) 0.90 (0.56–1.43), P = 0.65; Free + $30 Upgrade: 38/182 = 20.9%, RR 0.91 (0.59, 1.42), P = 0.69. Conclusions Upgrade glasses can prevent reductions in glasses purchase when free spectacles are provided, providing important program income. Trial registration ClinicalTrials.gov Identifier: NCT02231606. Registered on 31 August 2014.;Background Offering free glasses can be important to increase children’s wear. We sought to assess whether “Upgrade glasses” could avoid reduced glasses sales when offering free glasses to children in China. Methods In this cluster-randomized, controlled trial, children with uncorrected visual acuity (VA)< = 6/12 in either eye correctable to >6/12 in both eyes at 138 randomly-selected primary schools in 9 counties in Guangdong and Yunnan provinces, China, were randomized by school to one of four groups: glasses prescription only (Control); Free Glasses; Free Glasses + offer of $15 Upgrade Glasses; Free Glasses + offer of $30 Upgrade Glasses. Spectacle purchase (main outcome) was assessed 6 months after randomization. Results Among 10,234 children screened, 882 (8.62%, mean age 10.6 years, 45.5% boys) were eligible and randomized: 257 (29.1%) at 37 schools to Control; 253 (28.7%) at 32 schools to Free Glasses; 187 (21.2%) at 31 schools to Free Glasses + $15 Upgrade; and 185 (21.0%) at 27 schools to Free Glasses +$30 Upgrade. Baseline ownership among these children needing glasses was 11.8% (104/882), and 867 (98.3%) children completed follow-up. Glasses purchase was significantly less likely when free glasses were given: Control: 59/250 = 23.6%; Free glasses: 32/252 = 12.7%, P = 0.010. Offering Upgrade Glasses eliminated this difference: Free + $15 Upgrade: 39/183 = 21.3%, multiple regression relative risk (RR) 0.90 (0.56–1.43), P = 0.65; Free + $30 Upgrade: 38/182 = 20.9%, RR 0.91 (0.59, 1.42), P = 0.69. Conclusions Upgrade glasses can prevent reductions in glasses purchase when free spectacles are provided, providing important program income. Trial registration ClinicalTrials.gov Identifier: NCT02231606. Registered on 31 August 2014.;Background Offering free glasses can be important to increase children’s wear. We sought to assess whether “Upgrade glasses” could avoid reduced glasses sales when offering free glasses to children in China. Methods In this cluster-randomized, controlled trial, children with uncorrected visual acuity (VA)< = 6/12 in either eye correctable to >6/12 in both eyes at 138 randomly-selected primary schools in 9 counties in Guangdong and Yunnan provinces, China, were randomized by school to one of four groups: glasses prescription only (Co trol); Free Glasses; Free Glasses + offer of $15 Upgrade Glasses; Free Glasses + offer of $30 Upgrade Glasses. Spectacle purchase (main outcome) was assessed 6 months after randomization. Results Among 10,234 children screened, 882 (8.62%, mean age 10.6 years, 45.5% boys) were eligible and randomized: 257 (29.1%) at 37 schools to Control; 253 (28.7%) at 32 schools to Free Glasses; 187 (21.2%) at 31 schools to Free Glasses + $15 Upgrade; and 185 (21.0%) at 27 schools to Free Glasses +$30 Upgrade. Baseline ownership among these children needing glasses was 11.8% (104/882), and 867 (98.3%) children completed follow-up. Glasses purchase was significantly less likely when free glasses were given: Control: 59/250 = 23.6%; Free glasses: 32/252 = 12.7%, P = 0.010. Offering Upgrade Glasses eliminated this difference: Free + $15 Upgrade: 39/183 = 21.3%, multiple regression relative risk (RR) 0.90 (0.56–1.43), P = 0.65; Free + $30 Upgrade: 38/182 = 20.9%, RR 0.91 (0.59, 1.42), P = 0.69. Conclusions Upgrade glasses can prevent reductions in glasses purchase when free spectacles are provided, providing important program income. Trial registration ClinicalTrials.gov Identifier: NCT02231606. Registered on 31 August 2014.;Background Offering free glasses can be important to increase children's wear. We sought to assess whether "Upgrade glasses" could avoid reduced glasses sales when offering free glasses to children in China. Methods In this cluster-randomized, controlled trial, children with uncorrected visual acuity (VA)< = 6/12 in either eye correctable to >6/12 in both eyes at 138 randomly-selected primary schools in 9 counties in Guangdong and Yunnan provinces, China, were randomized by school to one of four groups: glasses prescription only (Control); Free Glasses; Free Glasses + offer of $15 Upgrade Glasses; Free Glasses + offer of $30 Upgrade Glasses. Spectacle purchase (main outcome) was assessed 6 months after randomization. Results Among 10,234 children screened, 882 (8.62%, mean age 10.6 years, 45.5% boys) were eligible and randomized: 257 (29.1%) at 37 schools to Control; 253 (28.7%) at 32 schools to Free Glasses; 187 (21.2%) at 31 schools to Free Glasses + $15 Upgrade; and 185 (21.0%) at 27 schools to Free Glasses +$30 Upgrade. Baseline ownership among these children needing glasses was 11.8% (104/882), and 867 (98.3%) children completed follow-up. Glasses purchase was significantly less likely when free glasses were given: Control: 59/250 = 23.6%; Free glasses: 32/252 = 12.7%, P = 0.010. Offering Upgrade Glasses eliminated this difference: Free + $15 Upgrade: 39/183 = 21.3%, multiple regression relative risk (RR) 0.90 (0.56-1.43), P = 0.65; Free + $30 Upgrade: 38/182 = 20.9%, RR 0.91 (0.59, 1.42), P = 0.69. Conclusions Upgrade glasses can prevent reductions in glasses purchase when free spectacles are provided, providing important program income.;Offering free glasses can be important to increase children's wear. We sought to assess whether "Upgrade glasses" could avoid reduced glasses sales when offering free glasses to children in China.In this cluster-randomized, controlled trial, children with uncorrected visual acuity (VA)< = 6/12 in either eye correctable to >6/12 in both eyes at 138 randomly-selected primary schools in 9 counties in Guangdong and Yunnan provinces, China, were randomized by school to one of four groups: glasses prescription only (Control); Free Glasses; Free Glasses + offer of $15 Upgrade Glasses; Free Glasses + offer of $30 Upgrade Glasses. Spectacle purchase (main outcome) was assessed 6 months after randomization.Among 10,234 children screened, 882 (8.62%, mean age 10.6 years, 45.5% boys) were eligible and randomized: 257 (29.1%) at 37 schools to Control; 253 (28.7%) at 32 schools to Free Glasses; 187 (21.2%) at 31 schools to Free Glasses + $15 Upgrade; and 185 (21.0%) at 27 schools to Free Glasses +$30 Upgrade. Baseline ownership among these children needing glasses was 11.8% (104/882), and 867 (98.3%) children completed follow-up. Glasses purchase was significantly less likely when free glass s were given: Control: 59/250 = 23.6%; Free glasses: 32/252 = 12.7%, P = 0.010. Offering Upgrade Glasses eliminated this difference: Free + $15 Upgrade: 39/183 = 21.3%, multiple regression relative risk (RR) 0.90 (0.56-1.43), P = 0.65; Free + $30 Upgrade: 38/182 = 20.9%, RR 0.91 (0.59, 1.42), P = 0.69.Upgrade glasses can prevent reductions in glasses purchase when free spectacles are provided, providing important program income.ClinicalTrials.gov Identifier: NCT02231606. Registered on 31 August 2014.;
Shao S, Li Z, Liu W. Coalescence Conditions of Relativistic Wave Functions. In: Handbook of Relativistic Quantum Chemistry. Berlin: Springer; 2017. pp. 497-530. 访问链接Abstract
The electron-electron coalescence conditions for the wave functions of the Dirac-Coulomb (DC), Dirac-Coulomb-Gaunt (DCG), and Dirac-Coulomb-Breit (DCB) Hamiltonians are analyzed by making use of the internal symmetries of the reduced two-electron systems. The results show that, at the coalescence point of two electrons, the wave functions of the DCG Hamiltonian are regular, while those of the DC and DCB Hamiltonians have $r_{12}^{\nu}$ type weak singularities, with $\nu$ being negative and of $\mathcal{O}(\alpha^2)$. Yet, such asymptotic expansions of the relativistic wave functions are only valid within an extremely small convergence radius $R_c$ of $\mathcal{O}(\alpha^2)$. Beyond this radius, the behaviors of the relativistic wave functions are still dominated by the nonrelativistic limit. 
Zheng JS, Liu H, Jiang J, Huang T, Wang F, Guan Y, Li D. Cohort Profile: The Jiaxing Birth Cohort in China. Int J EpidemiolInt J EpidemiolInt J Epidemiol. 2017;46:1382-1382g.
Wu S, He W, Yang W, Ye Y, Huang X, Logan BE. Combined carbon mesh and small graphite fiber brush anodes to enhance and stabilize power generation in microbial fuel cells treating domestic wastewater. Journal of Power Sources. 2017;356:348–355.
Wu S, He W, Yang W, Ye Y, Huang X, Logan BE. Combined carbon mesh and small graphite fiber brush anodes to enhance and stabilize power generation in microbial fuel cells treating domestic wastewater. Journal of Power Sources. 2017;356:348-355.
Bu Y, Ni S, Huang W. Combining multiple scholarly relationships with author cocitation analysis: A preliminary exploration on improving mapping knowledge domains. Journal of Informetrics. 2017;11(3):810-822.
Chen C, Yang CG, Gao X, Lu ZZ, Tang FX, Cheng J, Gao Q, Cardenas V. Community-based active case finding for tuberculosis in rural western China: a cross-sectional study. Int J Tuberc Lung Dis [Internet]. 2017;21:1134-1139. 访问链接Abstract
SETTING: Current passive case finding strategies are not effective at identifying tuberculosis (TB) patients in rural China. OBJECTIVE: To evaluate a community-based, active case finding (ACF) scheme in identifying symptomatic individuals with TB. DESIGN: We conducted door-to-door household visits of all residents aged >/=15 years at two rural sites to screen for TB symptoms. Individuals with symptoms were enrolled and asked to provide three sputum samples. All participants underwent chest X-ray, and microbiologic detection of Mycobacterium tuberculosis from sputum samples using microscopy, solid culture and Xpert(R) MTB/RIF was performed. RESULTS: Among the 19 334 residents screened for TB symptoms, 865 (4.5%) reported having >/=1 symptom. A total of 52 TB cases were detected, 11 of whom had microbiologic confirmation. Xpert identified all five M. tuberculosis culture-positive cases and yielded an additional three diagnoses. Prevalence of newly detected TB at the two sites through ACF was respectively 475 and 196 per 100 000 population. These estimates are respectively four and eight times, on average, higher than those identified through passive surveillance during the previous 5-year period for the two sites. CONCLUSION: Community-based symptom screening followed by laboratory tests was found to be feasible and effective in increasing TB case finding in rural China.
Guo C, Wang Z, Li N, Chen G, Zheng X. Comorbid Visual and Psychiatric Disabilities Among the Chinese Elderly: A National Population-Based Survey. Curr Eye ResCurr Eye ResCurr Eye Res. 2017;42:1733-1737.
Zhang J, Wang Y, Zhang X, HUANG R. Compact Digital-Controlled Neuromorphic circuit with Low Power Consumption, in IEEE International Symposium on Circuits and Systems (ISCAS). Baltimore, USA; 2017:2062-2065.
Du W, Shen G, Chen Y, Zhu X, Zhuo S, Zhong Q, Qi M, Xue C, Liu G, Zeng E, et al. Comparison of air pollutant emissions and household air quality in rural homes using improved wood and coal stoves. Atmospheric Environment [Internet]. 2017;166:215-223. 访问链接
An J, Zhou Q, Qian G, Wang T, Wu M, Zhu T, Qiu X, Shang Y, Shang J. Comparison of gene expression profiles induced by fresh or ozone-oxidized black carbon particles in A549 cells. Chemosphere. 2017;180:212-220.Abstract
Epidemiological studies have showed an association between black carbon (BC) exposure and adverse health effects. This study intends to investigate the influence of oxidation processes in atmosphere on the initial cellular responses of BC. The changes of gene expressions induced by fresh BC (FBC) and ozone oxidized BC (OBC) in human lung epithelial A549 cells were analyzed. And their toxic effects presented by viability, LDH release and DNA damage were compared. Totally 47, 000 genes in A549 cells were examined using Affymetrix Human U133 plus 2.0 chips. Some of the differentially expressed genes were verified by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). The results showed that 1446 genes (including 756 up -regulated and 690 down -regulated) and 1594 genes (including 788 up-regulated" and 806 down -regulated genes) were significantly changed by FBC and OBC respectively. Only 4 of 14 (FBC)/15 (OBC) oxidative stress related genes,up-or down -regulated by FBC and OBC, were identical; 13 of 29 (FBC)/31 (OBC) inflammation related genes, and 6 of 20 (FBC)/18 (OBC) autophagy related genes were identical. No obvious differences were observed between the toxic effects of FBC and OBC. The cytotoxicity of OBC and FBC in A549 cells is at least partially induced by oxidative stress and consequent inflammation or autophagy process. Previous studies indicated that OBC may be more toxic than FBC. However, our results suggested that FBC and OBC might lead to diverse toxic endpoints through activating different molecular pathways. (C) 2017 Elsevier Ltd. All rights reserved.

Pages