科研成果

2018
贾楠, 郭旦怀, 陈永强, 刘奕. 面向社区风险防范的大数据平台理论架构设计. 清华大学学报(自然科学版). 2018:1-7.Abstract
社区是公共安全治理的基本单元,社区安全研究意义重大.该文面向社区风险防范的重大需求,首先,从人、物及管理3个角度厘清社区风险的来源,剖析社区风险的特性及原因;然后,阐述社区风险防范的内涵,提出监测监控,预测预警和智能防范是社区风险防范的关键技术,在综合分析当前风险防范研究现状及发展趋势的基础上,指出大数据平台是社区风险防范的基础支撑;最后,分别从功能、结构及构建流程3个层面展开面向社区风险防范大数据平台的理论架构设计.为社区风险防范及大数据平台的基础理论研究大数据平台搭建及风险防范提供理论和技术支撑.
迟玉琢;王延飞. 面向科学数据管理的科学数据引用内容分析框架. 情报学报. 2018;37(1):43-51.
吴志鹏, 陈永强. 高性能边界元法模拟复合材料黏性界面分离, in 北方七省市区力学会议.; 2018.
马海涛 高珂. “黄宗羲定律”:我国古代“并税式”赋税改革回顾. 现代财经. 2018.
谢元, 蒋晓辉, 王婷, 许旭明, 倪晋仁. 黄河典型支流入干区底栖动物群落结构特征比较研究. 北京大学学报(自然科学版). 2018;54(5): 1067-1076.
席玥, 王婷, 倪晋仁, 韩鹏, 仪马兰, 郑彤, 蒋咏, 马若绮, 崔锋. 黄河干流宁蒙段溶解性有机物组分特征及其与金属离子的相关性. 环境科学. 2018;9:4114-4121.
2017
Jia T, Gu J. A 0.3-0.86V fully integrated buck regulator with 2GHz resonant switching for ultra-low power applications, in VLSI Symposium on Circuits (VLSI).; 2017.
A 109–137 GHz power amplifier in SiGe BiCMOS with 16.5 dBm output power and 12.8% PAE
Kucharski M, Borngräber J, Wang D, Kissinger D, Ng HJ. A 109–137 GHz power amplifier in SiGe BiCMOS with 16.5 dBm output power and 12.8% PAE. 2017 47th European Microwave Conference (EuMC) [Internet]. 2017:1021-1024. 访问链接Abstract
This paper presents a 3-stage differential cascode power amplifier (PA) for 109–137 GHz applications. At 120 GHz the circuit delivers 16.5 dBm saturated output power with 12.8 % power-added efficiency (PAE) without using power combining techniques. The chip was fabricated in 130 nm SiGe BiCMOS technology offering heterojunction bipolar transistors (HBT) with f T /f max of 300/500 GHz. The PA consists of three stages optimized accordingly to the design goals. The first stage operates in class A to provide high gain while the two following stages are biased in class AB and deep class AB in order to increase the efficiency. The circuit draws a maximum current of 100 mA from 3.3 V and 4 V supplies. It occupies only 0.24 mm 2 chip area excluding baluns and bondpads, which makes it attractive for future power combiners. The presented amplifier is suitable for radar applications, that require a high dynamic range.
Shen L, Lu N, Sun N. A 1V 0.25uW inverter-stacking amplifier with 1.07 noise efficiency factor, in 2017 Symposium on VLSI Circuits.; 2017:C140-C141.Abstract
This paper presents a highly power efficient amplifier. By stacking inverters and splitting the capacitor feedback network, the proposed amplifier achieves 6-time current reuse, thereby significantly boosting gm and lowering noise but without increasing power. A novel biasing scheme is devised to ensure robust operation under 1V supply. A prototype in 180nm CMOS has 5.5uV rms noise within 10kHz BW while consuming only 0.25uW, leading to a noise efficiency factor (NEF) of 1.07, which is the best among reported amplifiers.
杨成, 魏晨璐, 田耀华, 唐迅, 胡永华. 2012-2014年北京缺血性卒中患者阿司匹林和氯吡格雷联合使用率分析. 中国卒中杂志中国卒中杂志. 2017;12:219-222.Abstract
目的通过大数据分析我国临床缺血性卒中患者阿司匹林联合氯吡格雷(双抗)的使用率情况。方法从北京市职工医疗保险系统数据库中提取2012年1月-2014年12月,根据国际疾病分类(International Classification of Diseases,ICD)-10编码主诊断为I63(缺血性卒中)和G45[短暂性脑缺血发作(transient ischemic attack,TIA)和相关的综合征]的患者,以2013年6月为界限分为前后各18个月,比较这两个阶段患者用药记录中阿司匹林联合氯吡格雷用药的使用比例。并按照主诊断为缺血性卒中和TIA进行亚组分析。结果研究期间共纳入用药记录6 296 188例次,患者总计101 587例。2013年7月-2014年12月,每个月双抗使用876.9例次(标准差129.8),中位数867(最小值511、最大值1112),占比14.7%。而2012年1月-2013年6月每个月的双抗使用649.9例次(标准差129.8),中位数650.5(最小值352、最大值895),占比12.3%。2013年6月以后,主诊断为缺血性卒中和TIA的患者每月双抗使用比例分别为20.2%和11.1%,而2013年6月之前每月双抗的比例为14.5%和9.1%,2013年6月之后的双抗使用比例大于2013年6月之前。2013年6月前双抗的使用人数占入选患者的18.3%,而2013年6月之后接受双抗治疗的患者比例提高至22.2%。结论在北京市医疗保险缺血性卒中和TIA患者中,相比2013年6月前,2013年6月后使用阿司匹林联合氯吡格雷进行双抗的比例较高。
Gao M, Ge M, Ji Q, Cheng R, Lu H, Guan H, Gao L, Guo Z, Huang T, Huang X, et al. 2016 Chinese expert consensus and guidelines for the diagnosis and treatment of papillary thyroid microcarcinoma. Cancer Biol MedCancer Biol MedCancer Biol Med. 2017;14:203-211.
Ao Y, Yang C, Wang X, Xue W, Fu H, Liu F, Gan L, Xu P, Ma W. 26 PFLOPS Stencil Computations for Atmospheric Modeling on Sunway TaihuLight, in Proc. 31st IEEE International Parallel & Distributed Processing Symposium (IPDPS'17). IEEE; 2017:535–544. 访问链接
曹亚英, 唐迅, 孙可欣, 刘志科, 项骁, 隽娟, 宋菁, 殷琼洲, 扎西德吉, 胡亚楠, et al. 2型糖尿病患者血糖控制与内脏脂肪指数的关系. 北京大学学报(医学版)北京大学学报(医学版). 2017;49:446-450.Abstract
目的:探讨2型糖尿病(type 2 diabetes mellitus,T2DM)患者血糖控制情况与内脏脂肪指数(visceral adiposity index,VAI)的关系。方法:采用流行病学现场调查的方法,对社区40岁及以上T2DM患者人口学特征、生活习惯、疾病史、家族史、服药史等资料进行收集,并进行体格检查及空腹血糖、糖化血红蛋白(glycosylated hemoglobin,Hb A1c)、血脂等指标的血生化检测。以Hb A1c≥7.0%作为血糖控制不良的标准,分析其与不同水平VAI的关系。结果:共纳入1 607例研究对象,平均年龄为(59.4±8.1)岁,平均糖尿病病程为(7.0±6.4)年,其中78.3%在接受降糖治疗。按VAI四分位数升高的次序将研究对象分为Q1、Q2、Q3和Q4组,其血糖控制不良率依次为60.6%、65.7%、70.1%和71.0%(趋势χ~2=12.20,P<0.001)。Logistic回归模型调整年龄、性别、收缩压、舒张压、低密度脂蛋白胆固醇、吸烟情况、心脑血管疾病史、降糖治疗情况、糖尿病病程及家族史后显示,T2DM患者血糖控制情况与VAI水平关联显著。与Q1组研究对象相比,Q2、Q3和Q4组血糖控制不良的OR值分别为1.239(95%CI 0.918~1.672)、1.513(95%CI 1.117~2.050)和1.535(95%CI 1.128~2.088,趋势P=0.003);VAI每升高一个四分位数,血糖控制不良OR值为1.162(95%CI 1.054~1.282)。结论:T2DM患者血糖控制情况与VAI显著相关,VAI水平高预示血糖控制不佳。
Li* S, Kay S, Porter S. A 3D Assessment And Feedback Tool For Ankylosing Spondylitis From The Perspective Of Healthcare Professionals. Informatics for Health and Social Care. 2017;42(3):274-289.
Zhu R, Zhao Q, Xu J, Liu B, Leprince-Wang Y, Yu D. Ab initio thermodynamic study on two-dimensional atomic nucleation on ZnO polar surfaces. Applied Surface ScienceApplied Surface Science. 2017;412:417-423.Abstract
Structures of the two-dimensional atomic nuclei on ZnO (0001)-Zn and (0001)-O polar surfaces were studied by first principles density functional theory. The polarity-dependent nucleation dynamics was investigated by simulating two-dimensional (2D) nuclei consisting of 1-8 ZnO monomers on both polar surfaces. According to total energy calculations, average binding energy per ZnO monomer of the surface nuclei was analyzed to investigate if the nucleation and growth will proceed reasonably in physics. We found nucleation on (0001)-Zn surface was easier than that on (0001)-O surface. By using atomistic thermodynamics analysis, we calculated the Gibbs free energy of formation of these nuclei and made a comparison between the two polar surfaces. On (0001)-Zn surface, the critical Gibbs free energy of formation is much lower than that on (0001)-O surface under the same supersaturation, which leads to a much larger ZnO growth rate and rougher morphology, in accordance with experimental results. In addition, energetic analysis of nucleation at real thermodynamic conditions was achieved by introducing the temperature-and pressure-dependent chemical potentials of ZnO precursors. (C) 2017 Elsevier B.V. All rights reserved.
Gong J, Yang T, Zhou Y, Yang D, Chen S, Cui B, Li X. Abc: a practicable sketch framework for non-uniform multisets, in IEEE BigData.; 2017:2380–2389.
Lin H, Zhang D, Shen P, Xu Z, Si Y, Tang X, Gao P. Abstract P166: Multimorbidity and Risk of Mortality in China: Results From the Chinese Electronic Health Records Research in Yinzhou (CHERRY) Study. Circulation [Internet]. 2017;135:AP166–AP166. 访问链接Abstract
Introduction: The prevalence of multimorbidity is increasing in developed countries, while corresponding research in Chinese population is limited.Methods: A population-based cohort in Yinzhou located in an eastern coastal area of China (961,008 adults >=18 years in 2009; latest mortality follow-up: Nov 2015; 22,637 deaths; 6.53 million person-years at risk) was assembled by linking epidemiological surveys, electronic records for chronic disease management, health administrative and medical records databases. Multimorbidity was defined as the presence of two or more following disorders: hypertension, diabetes, cardiovascular disease or cancer. History of selected diseases was extracted from the electronic records for chronic disease management. Follow-up on fatal events is achieved through records linkage to the regional system of death surveillance.Results: Overall age- and sex-standardized prevalence of one, two or >=3 disorders were 16.16% (16.09% - 16.23%), 4.11% (4.07% - 4.15%) and0.36% (0.35% - 0.38%) respectively, whereas 41.73%, 14.41% and 1.67% were observed in people aged 60 years and older. The all-cause mortality rate adjusted to the age of 60 was 4.77 per 1000 person-years. Comparing to people without any selected diseases, the age- and sexadjusted HRs for all-cause mortality were 1.17 (1.14, 1.21) in those with one disorder, 1.78 (1.72, 1.86) in those with two morbidities, and 2.97 (2.76, 3.19) in those with >=3 morbidities. The HRs in those with multimorbidites were higher in younger people and were heterogeneous among different combinations of multimorbidites. Population-attributable fractions (PAF) for all-cause mortality due to one, two or >=3 disorders were 2.63%, 3.04% and 0.67% respectively (1.28%, 7.69% and 2.34% in people aged 60 years and older).Conclusions: The CHERRY study can serve as a valuable big data resource for scientific research in China. Multimorbidity is becoming acommon condition in Chinese population, especially in older population, and is associated with high mortality. A complementary strategy is required for population health interventions.Author Disclosures: H. Lin: None. D. Zhang: None. P. Shen: None. Z. Xu: None. Y. Si: None. X. Tang: None. P. Gao: None.
Dai H, Masui T. Achieving carbon emissions peak in China by 2030: the key options and economic impacts. In: Shinichiro Fujimori, Mikiko Kainuma TM Post 2020 climate action: global and asian perspectives. Singapore: Springer; 2017.
Fan Z, Jiang T, Huang T. Active Sampling Exploiting Reliable Informativeness for Subjective Image Quality Assessment Based on Pairwise Comparison. IEEE Trans. Multim. [Internet]. 2017;19:2720–2735. 访问链接
Wang Z, Zhang P. Activity Patterns of Collaborative Sensemaking in Small Discussion Groups, in iConference '17. Wuhan, China; 2017. 访问链接

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