科研成果

2000
Zeng X, Qu A, Lou X, Xu J, Wang J, Wu H, Zhou Z. Ca2+ signals induced from calcium stores in pancreatic islet β cells. Chinese Science Bulletin. 2000;(1):51-56.
Kuang MH, Wang ZL, Bai XD, Guo JD, Wang EG. Catalytically active nickel {110} surfaces in growth of carbon tubular structures. Applied Physics Letters. 2000;(10):1255-1257.
Xiao R-P. Cell logic for dual coupling of a single class of receptors to G(s) and G(i) proteins. Circulation Research [Internet]. 2000;(8):635-637. 访问链接
Jiang Z, Hong X, Long H, Hu J, Zhai Z. Ceramides induce apoptosis in HeLa cells and enhance cytochrome c-induced apoptosis in Xenopus egg extracts. Cellular and Molecular Life Sciences [Internet]. 2000;(7):1117-1125. 访问链接
Zheng M*, Fang M, Wang F, To KL. Characterization of the solvent extractable organic compounds in PM2.5 aerosols in Hong Kong. Atmospheric Environment [Internet]. 2000;34:2691 - 2702. LINKAbstract
The results from a year-long monthly study of the solvent extractable organic compounds (SEOC) in PM2.5 of the ambient aerosols in Hong Kong are reported. A total of 18 samples were analyzed. The extracted organic compounds were separated into four major fractions (n-alkanes, fatty acids, alkanols and PAHs (polycyclic aromatic hydrocarbons)) and identified with GC-MS (gas chromatography–mass spectrometry). The percentage of each fraction in total yield is as follows: fatty acids at 46–80%, alkanes at 10–34%, alkanols at 4–21%, and PAHs at 1–6%. Compared to the TSP (total suspended particulates) samples from our previous studies, the PAH fraction was higher in PM2.5 than TSP (0.5–2.5%). The bias of PAHs in PM2.5 suggests potential implications in health impact because PM2.5 is respirable. The total yield (defined as the sum of the four fractions) in PM2.5 was in the range of 56.4–233.6ngm−3. The sources of SEOC in PM2.5 could be attributed to vehicular, biogenic and microbial origins. On the average, 79% of the alkanes in PM2.5 came from vehicular emissions. U:R (ratio of unresolved to resolved components), an index to assess the magnitude of petroleum residues in aerosols, exhibited higher values in PM2.5 (average 3.2, range 1.0–5.9) than TSP (average 2.4, range 1.1–3.3). CPI (carbon preference index) of alkanes showed an inverse relationship with U:R, and a positive correlation with the percentage of alkanes from higher plant wax. Although U:R and CPI have been widely used as indices in source apportionment, their effectiveness was demonstrated for the first time from the statistical point of view in this paper. It was discovered that the CPI=1 (a characteristic of petroleum hydrocarbons) envelope and Cmax shifted towards lower carbon numbers in winter, suggesting there was more contribution from vehicular emission. PAHs had the following range 0.7–12.2ngm−3. The positive correlation with benzo(ghi)perylene suggested that they were of vehicular origin. Distinct seasonal variation in PAH concentration was found with higher concentrations in the winter samples. The concentration range of fatty acids in PM2.5 (31.1–168.8ngm−3) indicated that the microbial contribution in the PM2.5 samples was systematically lower in late fall and winter (average 52%) while larger in the hotter weather (over 80%), suggesting higher microbial activities in the summer. A ratio as high as 1.93 in summer for C18:1/C18:0 and only 0.69 in winter suggested that there were more aged aerosols in winter while more fresh emissions were found in summer. The results of SEOC in the PM2.5 aerosols indicated that vehicular emission was the characteristic of Hong Kong's aerosols.
Lu L, Huang M, Liu Z, Ma L. Cholecystokinin-B receptor antagonists attenuate morphine dependence and withdrawal in rats. NeuroReport [Internet]. 2000;(4):829-832. 访问链接
Qu L, Li D, Zhang Y, Liu M, Gu H, Chen Z. Cloning and expression of a cDNA encoding ribosomal protein S4 from rice (Oryza sativa). Chinese Science Bulletin. 2000;(2):168-173.
Chen S, Deng Y, Nie X, Tu Y. Clustering kinetics of granular media in three dimensions. Physics Letters, Section A: General, Atomic and Solid State Physics. 2000;(4):218-223.
Chen S, Deng Y, Nie X, Tu Y. Clustering kinetics of granular media in three dimensions. Physics Letters, Section A: General, Atomic and Solid State Physics. 2000;(4):218-223.
Liu Z-R, Liu J-S, Gu B-L, Zhang X-W. Cluster-variation-method studies on the atomic ordering in complex perovskite alloys. Physical Review B - Condensed Matter and Materials Physics. 2000;(18):11918-11921.
蔡昉, 李周, 林毅夫. Comparative Advantages and Development Strategy——A Reinterpretation of the“East Asian Miracle”. Social Sciences in China. 2000;(4):16-27+184.
Michalowski BA, Francisco JS, Li SM, Barrie LA, Bottenheim JW, Shepson PB. A computer model study of multiphase chemistry in the Arctic boundary layer during polar sunrise. JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES. 2000;105:15131-15145.Abstract
A multiphase chemical box model of Arctic halogen chemistry has been developed using a PC-based modeling program developed by Environment Canada called the Chemical Reactions Modeling System(CREAMS). The multiphase model contains 125 gas phase reactions, 19 photolysis reactions, and 16 aqueous reactions occurring in suspended aerosol particles and the quasi-liquid component of snow. The model simulates mass transfer of species between the gas phase and particles, and between the gas phase and the snowpack. Model simulations were conducted for the Arctic for the period April 16 to April 24 at 245 K within a 400 m boundary layer. The complete model simulates halogen-catalyzed ozone depletion within 5 days from the start of the model run, via known gas and heterogeneous phase activation mechanisms. A critically important model reaction is BrO + HCHO –> HOBr + CHO, which has a substantial impact on gas phase HOBr, and subsequent condensed phase chemistry. When coupled with a necessary snowpack efflux of aldehydes, required to maintain the aldehyde concentrations at observed levels, the new BrO chemistry has a significant impact on the concentrations of gas phase bromine species, particle bromide, and chlorine atoms, through chemistry occurring in the snowpack. We also find that O-3 depletion cannot be simulated without the presence of heterogeneous halogen chemistry occurring in the snowpack and that the rate of O-3 depletion is limited by the mass transfer rate of HOBr to the snowpack.
Liu Z-J, Jiang L, Li W-Z, Han Y-Z, Lai L-H. Conformational changes accompanying with the binding of protein and ligand. Acta Chimica Sinica. 2000;(7):772-776.
Wei L-N, Hu X, Chinpaisal C. Constitutive activation of retinoic acid receptor β2 promoter by orphan nuclear receptor TR2. Journal of Biological Chemistry [Internet]. 2000;(16):11907-11914. 访问链接
Lü H, Ming X, Qu L, Liu M, Li J, Gu H, Chen Z. Construction of chimeric inducible promoters by elicitors of rice fungal blast pathogen and their expression in transgenic rice. Chinese Science Bulletin. 2000;(3):242-246.
Liang S, Liu Z, Li W, Ni L, Lai L. Construction of protein binding sites in scaffold structures. Biopolymers [Internet]. 2000;(7):515-523. 访问链接
Zheng M*, Fang M*. Correlations between organic and inorganic species in atmospheric aerosols. Environ. Sci. Technol. [Internet]. 2000;34 (13):2721-2726. LINKAbstract
Correlations between 35 different organic and inorganic species or tracers in the aerosols of Hong Kong were derived based on the GC−MS organic results from our 1993−1994 study and Hong Kong Environmental Protection Department inorganic data. Source apportionment is essential in fingerprinting of air pollutants for cross-boundary studies. It is also important in the development of emissions inventory data, control strategies, and legislature. Traditionally, emission sources are identified from either the inorganic or organic tracers in the aerosols, but not both. Each of these techniques yields much source information; however, each by itself provides only a partial picture due to the complicated nature of ambient aerosols. Since many of the organic and inorganic species in aerosols are from the same source, correlations between the two are to be expected. In this study, such correlations were indeed found. For example, benzo[b,k]fluoranthene, the most abundant PAH (polycyclic aromatic hydrocarbon) in all the PAHs detected in Hong Kong, exhibited good correlation with Pb, Zn, As, nss SO42- (nonseasalt sulfate), total PAHs, and benzo[a]pyrene. This paper further demonstrates that a combination of the two techniques could be an improved method for source apportionment than using either method alone.
Lu L, Ceng X, Huang M. Corticotropin-releasing factor receptor type I mediates stress-induced relapse to opiate dependence in rats. NeuroReport [Internet]. 2000;(11):2373-2378. 访问链接
Lai L, Yokota H, Hung L-W, Kim R, Kim S-H. Crystal structure of archaeal RNase HII: A homologue of human major RNase H. Structure [Internet]. 2000;(8):897-904. 访问链接
Chen J, Nakata T, Zhang Z, Hirokawa N. The C-terminal tail domain of neurofilament protein-H (NF-H) forms the crossbridges and regulates neurofilament bundle formation. Journal of Cell Science [Internet]. 2000;(21):3861-3869. 访问链接

Pages