The non-relativistic approximation of the quark–meson-coupling model has been discussed and compared with the Skyrme–Hartree–Fock model which includes spin exchanges. Calculations show that the spin-exchange interaction has important effect on the descriptions of finite nuclei and nuclear matter through the Fock exchange. Also in the quark–meson-coupling model, it is the Fock exchange that leads to a nonlinear density-dependent isovector channel and changes the density-dependent behavior of the symmetry energy.
Kink effects are studied in conventional AlGaN/GaN high-electron-mobility transistors by measuring their current-voltage characteristics with various bias sweeping conditions at drain and gate terminals. It is found that the kink effect is induced by drain and gate pumping. The magnitude of kink is directly related to the maximum drain voltage and current levels during on-state operation. The hot electrons in the 2-D electron gas channel generated under high drain bias could be injected into the adjacent epitaxial buffer layer where they can be captured by donor-like traps. Hot electron trapping and the subsequent field-assisted de-trapping is suggested to be the dominant mechanism of kink generation in the studied device. The extracted activation energy of the traps accounting for the kink effect is 589 +/- 67 meV from temperature-dependent transient measurement, and is close to the energy of the E-2 trap widely reported in GaN layers.
Laser wakefield acceleration of electrons well beyond 1 GeV and optical guiding of ultraintense laser pulses of peak powers up to 160 TW over a 4-cm long ablative capillary discharge plasma channel were experimentally demonstrated. Electron beams, with energies up to 1.8 GeV, were generated by using the 130 TW, 55 fs driving laser pulses. A comparison of oxygen-containing acrylic resin (C:O:H = 4:2:7) capillary and no oxygen-containing polyethylene (C:O:H = 1:0:2) capillary measurements suggests that the injection of electron into the laser wakefield is assisted by the ionization of oxygen K-shell electrons.
BACKGROUND: A fixed-dose combination (FDC) of four compounds, hydrochlorothiazide 12.5 mg, triamterene 12.5 mg, dihydralazine 12.5 mg and reserpine 0.1 mg (HTDR), is widely used as an antihypertensive treatment in China. Although HTDR has been used in China for more than 30 years, there have been few comprehensive evaluations of this treatment. OBJECTIVE: The aim of this study was to investigate the long-term efficacy and tolerability of HTDR in Chinese patients with essential hypertension. METHODS: This was a 36-month, community-based, open-label surveillance study, conducted in the Huangpu District (Shanghai, China). The study was based in local primary healthcare settings. Subjects were recruited if they had essential hypertension, were aged >/=35 years at the time of enrolment, were expected to remain in the area for 3 years, and were able to provide informed consent. Patients who had secondary hypertension, myocardial infarction or stroke within 6 months of screening, impaired renal or hepatic function, history of cardiomyopathy or chronic heart failure, or were pregnant or lactating were excluded. HTDR was administered as one or two tablets per day in the morning. If necessary, additional hydrochlorothiazide was added. Blood pressure (BP) was measured at baseline and throughout the 36-month surveillance period every 3 months. Biochemical indicators (e.g. fasting blood glucose, plasma lipid parameters, plasma sodium and potassium, plasma uric acid and serum creatinine) were also measured, and adverse events were noted. BP reductions and the rate at which patients achieved BP targets (systolic BP [SBP] <140 mmHg and diastolic BP [DBP] <90 mmHg) throughout the period were determined. Subgroup analyses by sex and age were also conducted. RESULTS: A total of 1529 patients (550 male, 979 female; mean age 65.7 years) entered the study. After the 36-month treatment period, 93.1% of patients had achieved the SBP target, 97.9% had achieved the DBP target, and 92.1% had achieved both. The mean decreases in SBP and DBP were 15.3 mmHg and 9.9 mmHg, respectively. Overall, 127 adverse events in 119 patients (7.8%) occurred during the follow-up period, most of which were mild to moderate. Plasma lipid profiles were improved after 24 months of treatment. In addition, a significant increase in plasma potassium and a significant reduction in plasma uric acid were seen. CONCLUSION: HTDR was found to have good long-term efficacy and tolerability in Chinese patients with essential hypertension.