科研成果

2010

Lee J, Chen L, Snieder H, Chen DF, Lee LM, Liu GF, Wu T, Tang X, Zhan SY, Cao WH, et al. Heritability of obesity-related phenotypes and association with adiponectin gene polymorphisms in the Chinese national twin registry. Annals of Human Genetics. 2010;74:146-54.Abstract

The purpose of this study was to estimate the heritability of obesity-related phenotypes and investigate the association of adiponectin gene polymorphisms +45T>G and +276G>T with these measures in Chinese twins. 1260 twin pairs were recruited from two cities through the Chinese National Twin Registry System from 2001 to 2005. Two SNPs at the adiponectin locus (+45T>G and +276G>T) were genotyped. Structural equation modeling (SEM) was used to estimate heritability and the best-fitting variance component model. The regular association among all twins was analysed with generalised estimating equations (GEE). Sib-transmission/disequilibrium test (TDT) within dizygotic (DZ) twin pairs discordant for their genotype was performed using SEM. Additive genetic, common and unique environmental (ACE) model-based heritability of body mass index (BMI) was 61%, while additive genetic and unique environmental (AE)-model-based heritability of waist circumference (WC) and waist-hip ratio (WHR) were 75% and 61%, respectively. There was no association of adiponectin gene +45T>G and +276G>T genotypes with obesity-related phenotypes in all twins or discordant DZ twins. Our twins data did not support that there was an association between adiponectin gene polymorphisms +45T>G and +276G>T and the obesity-related phenotypes. Further studies are required to better understand the role of adiponectin gene polymorphisms in obesity.

Ye C, et al. Heterogeneous reaction of NO2 with sea salt particles. Sci. China Chem. . 2010;53:2652–2656 .

Zhao Y, Chen ZM, Zhao JN. Heterogeneous reactions of methacrolein and methyl vinyl ketone on α-Al₂O₃ particles. Environmental Science & Technology,. 2010;44(6):2035-2041.

Li Y, Balédent V, Yu G, Barišić N, Hradil K, Mole RA, Sidis Y, Steffens P, Zhao X, Bourges P, et al. Hidden magnetic excitation in the pseudogap phase of a high-Tc superconductor. Nature [Internet]. 2010;(7321):283-285. 访问链接

Wen L, Xiong H, Wu B. Hidden vortices in a Bose-Einstein condensate in a rotating double-well potential. Physical Review A - Atomic, Molecular, and Optical Physics. 2010;(5).

Wei Z, Huang H, Wu M, Liang Z, Wang W, Li Z. A high performance continuous electroporation chip. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 2010:1622-1624.

Wei Z, Huang H, Liang Z, Li Z. A high performance electroporation chip integrating multi-well plate and annular interdigital microelectrodes. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2010:951-954.

Huang JY, Pan XC, Peng XL, Zhu T, Qin L, Xiong CY, Fang J. High-efficiency cell-substrate displacement acquisition via digital image correlation method using basis functions. Optics and Lasers in EngineeringOptics and Lasers in Engineering. 2010;48:1058-1066.

Huang JY, Zhu T, Pan XC, Qin L, Peng XL, Xiong CY, Fang J. A high-efficiency digital image correlation method based on a fast recursive scheme. Measurement Science & TechnologyMeasurement Science & Technology. 2010;21.

Gao P, Liu K, Liu L, Wang Z, Liao Z, Xu Z, Wang W, Bai X, Wang E, Li Y. Higher-order harmonic resonances and mechanical properties of individual cadmium sulphide nanowires measured by in situ transmission electron microscopy. Journal of Electron Microscopy [Internet]. 2010;(4):285-289. 访问链接

Cullen WG, Yamamoto M, Burson KM, Chen JH, Jang C, Li L, Fuhrer MS, Williams ED. High-fidelity conformation of graphene to SiO2 topographic features. Physical Review Letters. 2010;(21).

Zhao BS, Liang Y, Song Y, Zheng C, Hao Z, Chen PR. A highly selective fluorescent probe for visualization of organic hydroperoxides in living cells. Journal of the American Chemical Society [Internet]. 2010;(48):17065-17067. 访问链接

Hu Y, Zhang Y, Xu C, Zhu G, Wang ZL*. High-output nanogenerator by rational unipolar assembly of conical nanowires and its application for driving a small liquid crystal display. Nano Letters. 2010;10:5025–5031.

Fang YD, Zhang YH, Oshima M, Toh Y, Xu FR, Shi Y, Zhou XH, Liu ML, Guo YX, Koizumi M, et al. High-spin states in $^188\mathrmAu$: Further evidence for nonaxial shape. Phys. Rev. C [Internet]. 2010;82:064303. 访问链接

Wang J, Mendelsohn R, Dinar A, Huang J. How Chinese farmers change crop choice to adapt to climate change. Climate Change Economics. 2010;1:167–185.

Zhao W, Tian Y, Wu L, Liu Y. Human impact index in landslide susceptibility mapping, in 2010 18th International Conference on Geoinformatics, Geoinformatics 2010.; 2010. 访问链接

Wang D, Qiu C, Zhang H, Wang J, Cui Q, Yin Y. Human MicroRNA oncogenes and tumor suppressors show significantly different biological patterns: From functions to targets. PLoS ONE [Internet]. 2010;(9):1-7. 访问链接

Li C-Y, Zhang Y, Wang Z, Zhang Y, Cao C, Zhang P-W, Lu S-J, Li X-M, Yu Q, Zheng X, et al. A human-specific de novo protein-coding gene associated with human brain functions. [Internet]. 2010;(3). 访问链接

Li C-Y, Zhang Y, Wang Z, Zhang Y, Cao C, Zhang P-W, Lu S-J, Li X-M, Yu Q, Zheng X, et al. A human-specific de novo protein-coding gene associated with human brain functions. PLoS Computational Biology [Internet]. 2010;(3). 访问链接

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