科研成果

2014
Yan W, Zhang F, Zhang R, Zhang X, Wang Y, Zhou F, Xia Y, Liu P, Gao C, Wang H, et al. Adiponectin regulates SR Ca2+ cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice. Journal of Molecular and Cellular Cardiology. 2014:183-192.
Li S, Cheng H, Tomaselli GF, Li RA. Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: Direct evidence of functional Ca2+-induced Ca 2+ release. Heart Rhythm. 2014;(1):133-140.
Hou T, Wang X, Ma Q, Cheng H. Mitochondrial flashes: New insights into mitochondrial ROS signalling and beyond. Journal of Physiology. 2014;(17):3703-3713.
Hou Y, Ghosh P, Wan R, Ouyang X, Cheng H, Mattson MP, Cheng A. Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1-42 on neural progenitor cell proliferation. Neurobiology of Aging. 2014;(5):975-989.
Jian C, Hou T, Yin RK, Cheng H, Wang X. Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations. Science China Life Sciences. 2014;(5):495-501.
Shang W, Lu F, Sun T, Xu J, Li L-L, Wang Y, Wang G, Chen L, Wang X, Cannell MB, et al. Imaging Ca2+ nanosparks in heart with a new targeted biosensor. Circulation Research [Internet]. 2014;(3):412-420. 访问链接
Shen E-Z, Song C-Q, Lin Y, Zhang W-H, Su P-F, Liu W-Y, Zhang P, Xu J, Lin N, Zhan C, et al. Mitoflash frequency in early adulthood predicts lifespan in caenorhabditis elegans. Nature [Internet]. 2014;(1):128-132. 访问链接
2013
Cao Y, Zhang X, Shang W, Xu J, Wang X, Hu X, Ao Y, Cheng H. Proinflammatory Cytokines Stimulate Mitochondrial Superoxide Flashes in Articular Chondrocytes In Vitro and In Situ. PLoS ONE. 2013;(6).
Zhang H, Shang W, Zhang X, Gu J, Wang X, Zheng M, Wang Y, Zhou Z, Cao J-M, Ji G, et al. β-Adrenergic-stimulated l-type channel Ca2+ entry mediates hypoxic Ca2+ overload in intact heart. Journal of Molecular and Cellular Cardiology [Internet]. 2013:51-58. 访问链接
Zhao W, Wang L, Han H, Jin K, Lin N, Guo T, Chen Y, Cheng H, Lu F, Fang W, et al. 1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel α2δ1 subunit. Cancer Cell [Internet]. 2013;(4):541-556. 访问链接
Wang X, Fang H, Huang Z, Shang W, Hou T, Cheng A, Cheng H. Imaging ROS signaling in cells and animals. Journal of Molecular Medicine [Internet]. 2013;(8):917-927. 访问链接
Huang X, Sun L, Ji S, Zhao T, Zhang W, Xu J, Zhang J, Wang Y, Wang X, Franzini-Armstrong C, et al. Kissing and nanotunneling mediate intermitochondrial communication in the heart. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2013;(8):2846-2851. 访问链接
Liu Y, Cheng H, Zhou Y, Zhu Y, Bian R, Chen Y, Li C, Ma Q, Zheng Q, Zhang Y, et al. Myostatin induces mitochondrial metabolic alteration and typical apoptosis in cancer cells. Cell Death and Disease [Internet]. 2013;(2). 访问链接
Mao J, Hu X, Xiao Y, Yang C, Ding Y, Hou N, Wang J, Cheng H, Zhang XQ. Overnutrition stimulates intestinal epithelium proliferation through β-catenin signaling in obese mice. Diabetes [Internet]. 2013;(11):3736-3746. 访问链接
Lan W-LP, Gong G, Gerstner BJ, Ducreux S, Yule DI, Pouvreau S, Wang .X, Sheu S-S, Cheng H, Dirksen RT, et al. Respective contribution of mitochondrial Superoxide and ph to mitochondria-targeted circularly permuted yellow fluorescent protein (mt-cpYFP) flash activity. Journal of Biological Chemistry [Internet]. 2013;(15):10567-10577. 访问链接
Zhang H, Gomez AM, Wang X, Yan Y, Zheng M, Cheng H. ROS regulation of microdomain Ca2+ signalling at the dyads. Cardiovascular Research [Internet]. 2013;(2):248-258. 访问链接
Zhang X, Huang Z, Hou T, Xu J, Wang Y, Shang W, Ye T, Cheng H, Gao F, Wang X. Superoxide constitutes a major signal of mitochondrial superoxide flash. Life Sciences [Internet]. 2013;(4):178-186. 访问链接
Hou T, Zhang X, Xu J, Jian C, Huang Z, Ye T, Hu K, Zheng M, Gao F, Wang X, et al. Synergistic triggering of superoxide flashes by mitochondrial Ca 2+ uniport and basal reactive oxygen species elevation. Journal of Biological Chemistry [Internet]. 2013;(7):4602-4612. 访问链接
Sipido KR, Cheng H. T-tubules and ryanodine receptor microdomains: on the road to translation. Cardiovascular research [Internet]. 2013;(2):159-161. 访问链接
Wang J-Q, Chen Q, Wang X, Wang Q-C, Wang Y, Cheng H-P, Guo C, Sun Q, Chen Q, Tang T-S. Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease. Journal of Biological Chemistry [Internet]. 2013;(5):3070-3084. 访问链接

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