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程和平
北京大学分子医学研究所教授、博士生导师
北京大学英杰交流中心338室,010-6276-5957
chengp@pku.edu.cn
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科研成果
1999
Shirokova N, González A, Kirsch WG, Ríos E, Pizarro G, Stern MD, Cheng H
.
Calcium sparks: Release packets of uncertain origin and fundamental role
. Journal of General Physiology [Internet]. 1999;(3):377-384.
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Muth JN, Yamaguchi H, Mikala G, Grupp IL, Lewis W, Cheng H, Song L-S, Lakatta EG, Varadi G, Schwartz A
.
Cardiac-specific overexpression of the α1 subunit of the L-type voltage-dependent Ca
2+
channel in transgenic mice. Loss of isoproterenol- induced contraction
. Journal of Biological Chemistry [Internet]. 1999;(31):21503-21506.
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Xiao R-P, Avdonin P, Zhou Y-Y, Cheng H, Akhter SA, Eschenhagen T, Lefkowitz RJ, Koch WJ, Lakatta EG
.
Coupling of β2-adrenoceptor to G(i) proteins and its physiological relevance in murine cardiac myocytes
. Circulation Research [Internet]. 1999;(1):43-52.
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Kuschel M, Zhou Y-Y, Cheng H, Zhang S-J, Chen YE, Lakatta EG, Xiao R-P
.
G(i) protein-mediated functional compartmentalization of cardiac β2- adrenergic signaling
. Journal of Biological Chemistry [Internet]. 1999;(31):22048-22052.
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Stern MD, Song L-S, Cheng H, Sham JSK, Yang HT, Boheler KR, Ríos E
.
Local control models of cardiac excitation-contraction coupling: A possible role for allosteric interactions between ryanodine receptors
. Journal of General Physiology [Internet]. 1999;(3):469-489.
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Zhou Y-Y, Cheng H, Song L-S, Wang D, Lakatta EG, Xiao R-P
.
Spontaneous β2-adrenergic signaling fails to modulate L-type Ca
2+
current in mouse ventricular myocytes
. Molecular Pharmacology [Internet]. 1999;(3):485-493.
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1998
Song L-S, Sham JSK, Stern MD, Lakatta EG, Cheng H
.
Direct measurement of SR release nux by tracking 'Ca
2+
spikes' in rat cardiac myocytes
. Journal of Physiology [Internet]. 1998;(3):677-691.
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Smith GD, Keizer JE, Stern MD, Lederer JW, Cheng H
.
A simple numerical model of calcium spark formation and detection in cardiac myocytes
. Biophysical Journal [Internet]. 1998;(1):15-32.
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Sham JSK, Song L-S, Chen Y, Deng L-H, Stern MD, Lakatta EG, Cheng H
.
Termination of Ca
2+
release by a local inactivation of ryanodine receptors in cardiac myocytes
. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 1998;(25):15096-15101.
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Xiao R-P, Tomhave ED, Wang D-J, Ji X, Boluyt MO, Cheng H, Lakatta EG, Koch WJ
.
Age-associated reductions in cardiac β1- and β2-adrenergic responses without changes in inhibitory G proteins or receptor kinases
. Journal of Clinical Investigation [Internet]. 1998;(6):1273-1282.
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1997
Zhou Y-Y, Cheng H, Bogdanov KY
.
Localized cAMP-dependent signaling mediates β2-adrenergic modulation of cardiac excitation-contraction coupling
. American Journal of Physiology - Heart and Circulatory Physiology. 1997;(3):H1611-H1618.
Gómez AM, Valdivia HH, Cheng H, Lederer MR, Santana LF, Cannell MB, McCune SA, Altschuld RA, Lederer WJ
.
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure
. Science [Internet]. 1997;(5313):800-806.
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Li Z, Cheng H, Lederer JW, Froehlich J, Lakatta EG
.
Enhanced proliferation and migration and altered cytoskeletal proteins in early passage smooth muscle cells from young and old rat aortic explants
. Experimental and Molecular Pathology [Internet]. 1997;(1):1-11.
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Xiao R-P, Valdivia HH, Bogdanov K, Valdivia C, Lakatta EG, Cheng H
.
The immunophilin FK506-binding protein modulates Ca
2+
release channel closure in rat heart
. Journal of Physiology [Internet]. 1997;(2):343-354.
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Zhou Y-Y, Cheng H, Bogdanov KY, Hohl C, Altschuld R, Lakatta EG, Xiao R-P
.
Localized cAMP-dependent signaling mediates β2-adrenergic modulation of cardiac excitation-contraction coupling
. American Journal of Physiology - Heart and Circulatory Physiology [Internet]. 1997;(3 42-3):H1611-H1618.
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Song L-S, Stern MD, Lakatta EG, Cheng H
.
Partial depletion of sarcoplasmic reticulum calcium does not prevent calcium sparks in rat ventricular myocytes
. Journal of Physiology [Internet]. 1997;(3):665-675.
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1996
Li Z, Cheng H, Lederer WJ, Froehlich J, Lakalla EG
.
Enhanced proliferation and migration and altered cytoskeletal proteins in aortic early passage smooth muscle cells from old rats
. FASEB Journal. 1996;(6):A1016.
Gómez AM, Cheng H, Lederer JW, Bers DM
.
Ca
2+
diffusion and sarcoplasmic reticulum transport both contribute to [Ca
2+
](i) decline during Ca
2+
sparks in rat ventricular myocytes
. Journal of Physiology. 1996;(2):575-581.
Gómez AM, Cheng H, Lederer WJ, Bers DM
.
Ca2+ diffusion and sarcoplasmic reticulum transport both contribute to [Ca2+]i decline during Ca2+ sparks in rat ventricular myocytes.
The Journal of physiology [Internet]. 1996:Pt 2/-.
访问链接
Cheng H, Lederer MR, Lederer WJ, Cannell MB
.
Calcium sparks and [Ca
2+
]i waves in cardiac myocytes
. American Journal of Physiology - Cell Physiology [Internet]. 1996;(1 39-1):C148-C159.
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Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca
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