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李沉简
北京大学生命科学学院教授
li_chenjian@pku.edu.cn
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科研成果 by Type: 期刊论文
2013
Cannon JR, Geghman KD, Tapias V, Sew T, Dail MK, Li C, Greenamyre TJ
.
Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment
. [Internet]. 2013;(1):44-56.
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2012
Huang Y, Shenoy S, Lu B, Liu W, Li C
.
Kinase signaling dysfunction in Parkinson's disease: A reverse genetic approach in Drosophila
. [Internet]. 2012;(2):158-167.
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Zheng S, Geghman K, Shenoy S, Li C
.
Retake the Center Stage - New Development of Rat Genetics
. [Internet]. 2012;(6):261-268.
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Xu Q, Shenoy S, Li C
.
Mouse models for LRRK2 Parkinson's disease
. [Internet]. 2012;(SUPPL. 1):S186-S189.
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2011
Magariños AM, Li CJ, Toth GJ, Bath KG, Jing D, Lee FS, McEwen BS
.
Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons
. [Internet]. 2011;(3):253-264.
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Liu W, Acín-Peréz R, Geghman KD, Manfredi G, Lu B, Li C
.
Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission
. [Internet]. 2011;(31):12920-12924.
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2010
Vives-Bauza C, Zhou C, Huang Y, Cui M, Vries RDLA, Kim J, May J, Tocilescu MA, Liu W, Ko HS, et al.
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
. [Internet]. 2010;(1):378-383.
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2009
Li Y, Liu W, Oo TF, Wang L, Tang Y, Jackson-Lewis V, Zhou C, Geghman K, Bogdanov M, Przedborski S, et al.
Mutant LRRK2
R1441G
BAC transgenic mice recapitulate cardinal features of Parkinson's disease
. [Internet]. 2009;(7):826-828.
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2007
Kim Y, Zhou P, Qian L, Chuang J-Z, Lee J, Li C, Iadecola C, Nathan C, Ding A
.
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival
. [Internet]. 2007;(9):2063-2074.
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2005
Sang T-K, Li C, Liu W, Rodriguez A, Abrams JM, Zipursky LS, Jackson GR
.
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis
. [Internet]. 2005;(3):357-372.
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Gu X, Li C, Wei W, Lo V, Gong S, Li S-H, Iwasato T, Itohara S, Li X-J, Mody I, et al.
Pathological cell-cell interactions elicited by a neuropathogenic form of mutant huntingtin contribute to cortical pathogenesis in HD mice
. [Internet]. 2005;(3):433-444.
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Li C, Beal FM
.
Leucine-rich repeat kinase 2: A new player with a familiar theme for Parkinson's disease pathogenesis
. [Internet]. 2005;(46):16535-16536.
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2004
Li C, Brake WG, Romeo RD, Dunlop JC, Gordon M, Buzescu R, Magarinos AM, Allen PB, Greengard P, Luine V, et al.
Estrogen alters hippocampal dendritic spine shape and enhances synaptic protein immunoreactivity and spatial memory in female mice
. [Internet]. 2004;(7):2185-2190.
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2002
Gong S, Yang XW, Li C, Heintz N
.
Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kγ origin of replication
. [Internet]. 2002;(12):1992-1998.
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2001
Milner TA, McEwen BS, Hayashi S, Li CJ, Reagan LP, Alves SE
.
Ultrastructural evidence that hippocampal alpha estrogen receptors are located at extranuclear sites
. [Internet]. 2001;(3):355-371.
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McEwen B, Akama K, Alves S, Brake WG, Bulloch K, Lee S, Li C, Yuen G, Milner TA
.
Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation
. [Internet]. 2001;(13):7093-7100.
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1999
Li C, Geng C, Leung H-T, Hong YS, Strong LLR, Schneuwly S, Pak WL
.
INAF, a protein required for transient receptor potential Ca
2+
channel function
. [Internet]. 1999;(23):13474-13479.
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成果类型
期刊论文
(17)
成果概览
1999
(1)
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2 of 2
最新科研成果
Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment
Mouse models for LRRK2 Parkinson's disease
Kinase signaling dysfunction in Parkinson's disease: A reverse genetic approach in Drosophila
更多成果