科研成果

2014
Jian C, Hou T, Yin RK, Cheng H, Wang X. Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations. Science China Life Sciences. 2014;(5):495-501.
Shang W, Lu F, Sun T, Xu J, Li L-L, Wang Y, Wang G, Chen L, Wang X, Cannell MB, et al. Imaging Ca2+ nanosparks in heart with a new targeted biosensor. Circulation Research [Internet]. 2014;(3):412-420. 访问链接
Shen E-Z, Song C-Q, Lin Y, Zhang W-H, Su P-F, Liu W-Y, Zhang P, Xu J, Lin N, Zhan C, et al. Mitoflash frequency in early adulthood predicts lifespan in caenorhabditis elegans. Nature [Internet]. 2014;(1):128-132. 访问链接
2013
Cao Y, Zhang X, Shang W, Xu J, Wang X, Hu X, Ao Y, Cheng H. Proinflammatory Cytokines Stimulate Mitochondrial Superoxide Flashes in Articular Chondrocytes In Vitro and In Situ. PLoS ONE. 2013;(6).
Wang J-Q, Chen Q, Wang X, Wang Q-C, Wang Y, Cheng H-P, Guo C, Sun Q, Chen Q, Tang T-S. Dysregulation of mitochondrial calcium signaling and superoxide flashes cause mitochondrial genomic DNA damage in Huntington disease. Journal of Biological Chemistry [Internet]. 2013;(5):3070-3084. 访问链接
Wang X, Fang H, Huang Z, Shang W, Hou T, Cheng A, Cheng H. Imaging ROS signaling in cells and animals. Journal of Molecular Medicine [Internet]. 2013;(8):917-927. 访问链接
Huang X, Sun L, Ji S, Zhao T, Zhang W, Xu J, Zhang J, Wang Y, Wang X, Franzini-Armstrong C, et al. Kissing and nanotunneling mediate intermitochondrial communication in the heart. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2013;(8):2846-2851. 访问链接
Lan W-LP, Gong G, Gerstner BJ, Ducreux S, Yule DI, Pouvreau S, Wang .X, Sheu S-S, Cheng H, Dirksen RT, et al. Respective contribution of mitochondrial Superoxide and ph to mitochondria-targeted circularly permuted yellow fluorescent protein (mt-cpYFP) flash activity. Journal of Biological Chemistry [Internet]. 2013;(15):10567-10577. 访问链接
Zhang H, Gomez AM, Wang X, Yan Y, Zheng M, Cheng H. ROS regulation of microdomain Ca2+ signalling at the dyads. Cardiovascular Research [Internet]. 2013;(2):248-258. 访问链接
Zhang X, Huang Z, Hou T, Xu J, Wang Y, Shang W, Ye T, Cheng H, Gao F, Wang X. Superoxide constitutes a major signal of mitochondrial superoxide flash. Life Sciences [Internet]. 2013;(4):178-186. 访问链接
Hou T, Zhang X, Xu J, Jian C, Huang Z, Ye T, Hu K, Zheng M, Gao F, Wang X, et al. Synergistic triggering of superoxide flashes by mitochondrial Ca 2+ uniport and basal reactive oxygen species elevation. Journal of Biological Chemistry [Internet]. 2013;(7):4602-4612. 访问链接
Zhang H, Shang W, Zhang X, Gu J, Wang X, Zheng M, Wang Y, Zhou Z, Cao J-M, Ji G, et al. β-Adrenergic-stimulated l-type channel Ca2+ entry mediates hypoxic Ca2+ overload in intact heart. Journal of Molecular and Cellular Cardiology [Internet]. 2013:51-58. 访问链接
2012
Wei C, Wang X, Zheng M, Cheng H. Calcium gradients underlying cell migration. Current Opinion in Cell Biology [Internet]. 2012;(2):254-261. 访问链接
Zhao T, Huang X, Han L, Wang X, Cheng H, Zhao Y, Chen Q, Chen J, Cheng H, Xiao R, et al. Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes. Journal of Biological Chemistry [Internet]. 2012;(28):23615-23625. 访问链接
Lin P, Zhu H, Cai C, Wang X, Cao C, Xiao R, Pan Z, Weisleder N, Takeshima H, Jianjie M. Nonmuscle myosin IIA facilitates vesicle trafficking for MG53-mediated cell membrane repair. FASEB Journal [Internet]. 2012;(5):1875-1883. 访问链接
Weisleder N, Takizawa N, Lin P, Wang X, Cao C, Zhang Y, Tan T, Ferrante C, Zhu H, Chen P-J, et al. Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Science Translational Medicine [Internet]. 2012;(139). 访问链接
Wang X, Jian C, Zhang X, Huang Z, Xu J, Hou T, Shang W, Ding Y, Zhang W, Ouyang M, et al. Superoxide flashes: Elemental events of mitochondrial ROS signaling in the heart. Journal of Molecular and Cellular Cardiology [Internet]. 2012;(5):940-948. 访问链接
Li K, Zhang W, Fang H, Xie W, Liu J, Zheng M, Wang X, Wang W, Tan W, Cheng H. Superoxide flashes reveal novel properties of mitochondrial reactive oxygen species excitability in cardiomyocytes. Biophysical Journal [Internet]. 2012;(5):1011-1021. 访问链接
2011
Chen M, Wang Y, Hou T, Zhang H, Qu A, Wang X. Differential mitochondrial calcium responses in different cell types detected with a mitochondrial calcium fluorescent indicator, mito-GCaMP2. Acta Biochimica et Biophysica Sinica [Internet]. 2011;(10):822-830. 访问链接
Fang H, Chen M, Ding Y, Shang W, Xu J, Zhang X, Zhang W, Li K, Xiao Y, Gao F, et al. Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals. Cell Research [Internet]. 2011;(9):1295-1304. 访问链接

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