科研成果 by Year: 2014>

2014

Zhu H, Wang Q. Prediction of translation initiation site in bacterial and Archaeal genomes. Current Bioinformatics. 2014;(2):155-165.

Cheng N, Yan Q, Liu S, Zhao D*. Probing the intermolecular interactions of aromatic amides containing N-heterocycles and triptycene. CrystEngComm [Internet]. 2014;16(20):4265-4273. [Read Online]Abstract

A series of aromatic amides incorporated with N-heterocycles or triptycene units are synthesized and studied for probing the effects of such chemical modifications on the intermolecular interactions. Single crystals of a number of heterocyclic amides and the triptycene-containing amide were obtained. Crystal structures, hydrogen bonds, lattice energy, solubility, and melting points were compared amongst relevant molecules. Suitably positioned nitrogen atoms from heterocycles are found to form intramolecular H-bonds with amide NHs at the expense of weakening or disrupting the intermolecular H-bonds. The effects of such H-bonding changes on solubility and melting point are nonetheless limited. Uniquely, the triptycene unit effectively improves the solubility of the amide without tempering the thermal resistance of the molecule.

Zhou L, Bosscher M, Zhang C, Özçubukçu S, Zhang L, Zhang W, Li CJ, Liu J, Jensen MP, Lai L, et al. A protein engineered to bind uranyl selectively and with femtomolar affinity. Nature Chemistry [Internet]. 2014;(3):236-241. 访问链接

Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, Wu Q, Hu K, Zhu X, Chang Z, et al. Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. Journal of Cell Science. 2014;(12):2761-2770.

Chen J, Ma X, Yuan Y, Pei J, Lai L. Protein-protein interface analysis and hot spots identification for chemical Ligand design. Current Pharmaceutical Design. 2014;(8):1192-1200.

Sun Z, Huang C, He J, Lamb KL, Kang X, Gu T, Shen WH, Yin Y. PTEN C-Terminal deletion causes genomic instability and tumor development. Cell Reports. 2014;(5):844-854.

Chen Z H, Zhu M, Yang J, Liang H, He J, He S, Wang P, Kang X, McNutt M A, Yin Y, et al. PTEN Interacts with Histone H1 and Controls Chromatin Condensation. Cell Reports. 2014.

Chen ZH, Zhu M, Yang J, Liang H, He J, He S, Wang P, Kang X, McNutt MA, Yin Y, et al. PTEN Interacts with Histone H1 and controls chromatin condensation. Cell Reports. 2014;(6):2003-2014.

Liang H, He S, Yang J, Jia X, Wang P, Chen X, Zhang Z, Zou X, McNutt MA, Shen WH, et al. PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolism. Cell Metabolism. 2014;(5):836-848.

Kang X, Jiang L, Chen X, Yuan H, Luo C, Ouyang Q. Pump-free multi-well-based microfluidic system for high-throughput analysis of size-control relative genes in budding yeast. Integrative Biology (United Kingdom). 2014;(7):685-693.

Liu Y, Gong L, Tong Q. Quantifying the distance effect in spatial interactions. Beijing Daxue Xuebao (Ziran Kexue Ban)/Acta Scientiarum Naturalium Universitatis Pekinensis [Internet]. 2014;50:526-534. 访问链接

Liu Y, Wang Y, Sheng H, Dong F, Zou R, Zhao L, Guo H, Zhu X, He B. Quantitative evaluation of lake eutrophication responses under alternative water diversion scenarios: A water quality modeling based statistical analysis approach. SCIENCE OF THE TOTAL ENVIRONMENT. 2014;468:219-227.Abstract

China is confronting the challenge of accelerated lake eutrophication, where Lake Dianchi is considered as the most serious one. Eutrophication control for Lake Dianchi began in the mid-1980s. However, decision makers have been puzzled by the lack of visible water quality response to past efforts given the tremendous investment. Therefore, decision makers desperately need a scientifically sound way to quantitatively evaluate the response of lake water quality to proposed management measures and engineering works. We used a water quality modeling based scenario analysis approach to quantitatively evaluate the eutrophication responses of Lake Dianchi to an under-construction water diversion project. The primary analytic framework was built on a three-dimensional hydrodynamic, nutrient fate and transport, as well as algae dynamics model, which has previously been calibrated and validated using historical data. We designed 16 scenarios to analyze the water quality effects of three driving forces, including watershed nutrient loading, variations in diverted inflow water, and lake water level. A two-step statistical analysis consisting of an orthogonal test analysis and linear regression was then conducted to distinguish the contributions of various driving forces to lake water quality. The analysis results show that (a) the different ways of managing the diversion projects would result in different water quality response in Lake Dianchi, though the differences do not appear to be significant; (b) the maximum reduction in annual average and peak Chl-a concentration from the various ways of diversion project operation are respectively 11% and 5%; (c) a combined 66% watershed load reduction and water diversion can eliminate the lake hypoxia volume percentage from the existing 6.82% to 3.00%; and (d) the water diversion will decrease the occurrence of algal blooms, and the effect of algae reduction can be enhanced if diverted water are seasonally allocated such that wet season has more flows. (C) 2013 Elsevier B.V. All rights reserved.

Qiao Z, Ren W, Chen H, Bellaiche L, Zhang Z, MacDonald AH, Niu Q. Quantum anomalous Hall effect in graphene proximity coupled to an antiferromagnetic insulator. Physical Review Letters. 2014;(11).

Zhang Y, Shi J. Quantum anomalous hall insulator of composite fermions. Physical Review Letters. 2014;(1).

Zhang H, Huang H, Haule K, Vanderbilt D. Quantum anomalous Hall phase in (001) double-perovskite monolayers via intersite spin-orbit coupling. Physical Review B. 2014;90:165143.

Zhuang Q, Wu B. Quantum thermalization and equilibrium state with multiple temperatures. Laser Physics Letters. 2014;(8).

Lin C, Huang X, Ke F, Jin C, Tong N, Yin X, Gan L, Guo X, Zhao R, Yang W, et al. Quasi-one-dimensional graphene superlattices formed on high-index surfaces. 2014;(8).

Lin C, Huang X, Ke F, Jin C, Tong N, Yin X, Gan L, Guo X, Zhao R, Yang W, et al. Quasi-one-dimensional graphene superlattices formed on high-index surfaces. Physical Review B - Condensed Matter and Materials Physics. 2014;(8).

Liu W-X, Yang Z-Q, Wang Y, Liu P-K, Zhao C. Radiation enhancement of a relativistic backward-wave oscillator driven bytwo annular electron beams. IEEE Transactions on Plasma Science,. 2014;42(1):42-50.

Pages