科研成果

2026
郑永平;雷润宏;陈意;邓秀文;江萍;孙海涛;王俊杰.; 2026. 基于空间距离分析的肿瘤放疗计划危及器官限量评价方法、装置及设备. China patent CN CN202511631547.Abstract
本发明公开了一种基于空间距离分析的肿瘤放疗计划危及器官限量评价方法、装置及设备,涉及肿瘤放射治疗技术领域。具体地,仅依据几何统计量,在剂量计算之前使用三维欧氏距离变换在各向异性归一后得到危及器官全体素到靶区的最短距离分布,直接形成个体化限量与权重模板。本发明输出的对象是距离‑体素直方图及其派生的累计占比与变化率,并从中提取若干几何指标,结合预设的几何规则集,直接得到对应不同剂量的限量阈值及优化权重的个体化建议。与现有技术相比,本发明不做剂量预测,且无需生成辅助轮廓或者进行剂量前向/逆向计算,而是在剂量计算之前即可得到个体化可执行的限量与权重建议,显著减少优化迭代并提升一致性,且结果可解释性强。
郑永平,雷润宏,陈意,邓秀文,江萍,孙海涛,王俊杰. 基于空间距离分析的肿瘤放疗计划危及器官限量评价系统. 2026.Abstract
开发目的:为定量评估肿瘤靶区(GTV)与关键危及器官(OAR)的空间位置关系,提供基于距离的剂量限量参考软件的主要功能:1. 自动提取RTSTRUCT中的危及器官(如视神经)和靶区(GTV)轮廓数据;2. 基于参考CT空间构建三维解剖结构Mask;3. 利用欧氏距离变换算法(Euclidean Distance Transform)计算危及器官的三维距离场;4. 自动判断肿瘤偏侧性(左/右),提取GTV体内素到对应危及器官的最短距离;5. 生成距离分布直方图(总体、分侧、个体)及详细统计报表(最小/平均距离等)。软件的技术特点:1.算法先进:采用SciPy高效距离变换算法,计算速度快,精度达体素级;2.自动化识别:支持模糊匹配ROI名称,自动处理左右侧器官对应关系;3.可视化丰富:高质量的距离分布直方图和累积分布曲线,直观展示空间关系
郑永平,雷润宏,陈意,孙海涛,江萍,王俊杰. 基于自动化脚本的放疗DICOM数据配准与ROI热力图生成系统. 2026.Abstract
开发目的:为解决放疗中多患者靶区分布规律分析困难的问题,实现从多患者DICOM数据到统一参考空间热力图的自动化生成软件的主要功能:1. 自动化解析多患者DICOM数据(CT, RTSTRUCT, REG);2. 基于刚性配准矩阵将不同患者的ROI轮廓变换到统一的参考CT空间;3. 支持批量处理和变换方向自动识别;4. 将变换后的矢量轮廓栅格化为二值Mask;5. 叠加多患者Mask生成概率分布热力图;6. 输出与参考CT共空间的NIfTI格式热力图,便于在三维可视化软件中显示。软件的技术特点:1. 自动化程度高:一键完成从DICOM解析、配准变换到热力图生成的全流程;2. 兼容性强:支持主流REG配准文件解析;3. 精度高:采用三维空间坐标变换算法和高精度栅格化技术;4. 扩展性好:基于Python模块化设计。
尹成明, 徐大融, 刘丽红, 程明华, 白忠凯, 张远银. 塔里木盆地西北缘柯坪断隆寒武系盐下油气重要发现与勘探意义. 石油学报. 2026;47(03):538-553.
李颀, 刘欣, 周羿, 高廷明. 当前中国的父母受教育程度、家庭权力结构与子女姓氏. 青年研究. 2026;2026(2):134-154.Abstract
虽然子女冠父姓的文化规范在中国社会仍居于主导地位,但随着女性受教育程度的持续提高,这一规范正受到冲击并发生改变。本文认为,为家庭贡献较多资源、在家庭权力结构中处于优势地位的一方更有可能获得子女冠姓权。本文通过对中国家庭追踪调查2010—2016年的数据分析发现,母亲受教育程度越高越有可能在家中主事,子女越有可能冠母姓;相较于父母教育同质婚,母亲教育向下婚更有可能使母亲在家中主事,子女也越有可能冠母姓。上述发现支持了基于权力结构论的研究假设。
鞠孜涵, 王延飞 王冰琪 李国俊. 技术项目的情报事实谱系构建研究. 情报理论与实践. 2026;49(2):1-8.Abstract
【目的/意义】 解决决策过程中信息不完备的问题,始终是情报工作的中心任务。基于情报事实谱系,提供技术项目预见,是应对不确定性的核心关切。 【方法/过程】 探讨情报事实谱系构建的必要性及构建原则。从谱系架构设计、情报事实的扫描评估、摹因制作、摹因著录4个方面,详细阐述情报事实谱系构建的具体方法,并展示摹因刻画的结果。 【结果/结论】 情报研究重视在事实基础上的分析,按照情报任务要求建立情报事实谱系,是时代赋予情报机构和情报人的重要责任。
贾积有 陈昂轩. 推理语言模型赋能教育的实践价值、风险挑战与发展进路. 北京大学教育评论. 2026;24(1):66-77+188.
Song J, Xie J. 算术动力系统. [Internet]. 2026. pdf
刘智锋, 罗鹏程, 唐星龙, 赵思琪, 王继民*. 组态视角下科学数据复用的驱动因素研究. 情报理论与实践. 2026;49(1):50-59.
郑永平,雷润宏,陈意,曲昂,李敏,邓秀文,孙海涛,江萍,王俊杰. 自适应放疗(ART)临床工作流分析系统. 2026.Abstract
开发目的:用于肿瘤自适应ART(Adaptive Radiation Therapy)放疗过程中各步骤耗时的精确记录、数据管理和统计分析,优化临床工作流程,提升放疗效率和质量 主要功能: 1. 实时计时功能:记录ART放疗过程中各步骤的时间戳,包括摆位、IGRT扫描、ROI生成、CTV/OARs勾画与修改、计划创建与优化、计划评估等16个关键步骤。2. 患者信息管理:记录患者姓名、ID、ART分次、日期等基本信息。3. ART设置记录:记录扫描范围、扫描层厚、CTV生成方式、计划生成方式等参数。4. 数据导出:自动导出Excel格式数据,包含步骤耗时表和事件时间戳表。5. 数据合并:合并多个Excel记录文件,生成统一的数据汇总表。6. 统计分析:计算各步骤的平均值、中位数、标准差、方差、最小值、最大值等统计指标。7. 数据可视化:生成箱线图、折线图等可视化图表,支持3mm与5mm扫描层厚的对比分析,包含显著性检验。8. 参考耗时对比:显示实际耗时与参考耗时的对比,用颜色标识是否超出参考时间。 技术特点:1. 采用面向对象设计,模块化架构,代码结构清晰。2. 实时计时更新机制,每秒自动刷新显示当前耗时。3. 支持键盘快捷键操作(Page Down/Up),提高操作效率。4. 自动数据导出和格式化,支持Excel多工作表。5. 内置统计分析模块,无需外部统计软件。6. 数据可视化功能,支持箱线图、折线图、趋势分析。7. 支持PyInstaller打包为独立可执行文件,无需安装Python环境。8. 中英文列名自动转换,便于国际化应用。
2025
李雅瑄, 陈昂轩, 贾积有. 2024中国教育技术研究前沿与热点年度报告. 中国电化教育. 2025;2025(5):61-67.
Zhou Y, Zhu R, Luo W, Xu X, Qi S, Ning Z, Chen L, Shao H, Tang K, HUANG R. 3D NOR-Type FeFETs with Record Endurance of 1011, Fast Erase of 50 ns, and Immediate Read-After-Write for In-Memory Learning, in 2025 Symposium on VLSI Technology and Circuits (VLSI Technology and Circuits).; 2025:1-3.
Du J, Haley BA, McManus J, Blaser P, Rickli J, Vance D. Abyssal seafloor as a key driver of ocean trace-metal biogeochemical cycles. Nature [Internet]. 2025;642:620–627. 访问链接Abstract
Trace elements and isotopes (TEIs) are important to marine life and are essential tools for studying ocean processes1. Two different frameworks have arisen regarding marine TEI cycling: reversible scavenging favours water-column control on TEI distributions2–5, and seafloor boundary exchange emphasizes sedimentary imprints on water-column biogeochemistry6,7. These two views lead to disparate interpretations of TEI behaviours8–10. Here we use rare earth elements and neodymium isotopes as exemplar tracers of particle scavenging11 and boundary exchange6,7,12. We integrate these data with models of particle cycling and sediment diagenesis to propose a general framework for marine TEI cycling. We show that, for elements with greater affinity for manganese oxide than biogenic particles, scavenging is a net sink throughout the water column, contrary to a common assumption for reversible scavenging3,13. In this case, a benthic flux supports increasing elemental concentrations with water depth. This sedimentary source consists of two components: one recycled from elements scavenged by water-column particles, and another newly introduced to the water column through marine silicate weathering inside sediment8,14,15. Abyssal oxic diagenesis drives this benthic source, and exerts a strong influence on water-column biogeochemistry through seafloor geometry and bottom-intensified turbulent mixing16,17. Our findings affirm the role of authigenic minerals, often overshadowed by biogenic particles, in water-column cycling18, and suggest that the abyssal seafloor, often regarded as inactive, is a focus of biogeochemical transformation19,20.
Liang J, Zhang Z, Zhang X, Shen Q, Gao Y, Yuan X, Xue H, Wu P, Wu Z. Achilles: A Formal Framework of Leaking Secrets from Signature Schemes via Rowhammer, in 34th USENIX SECURITY SYMPOSIUM. SEATTLE, WA, USA(Honorable Mention Paper): USENIX; 2025. 访问链接Abstract
Signature schemes are a fundamental component of cybersecurity infrastructure. While they are designed to be mathematically secure against cryptographic attacks, they are vulnerable to Rowhammer fault-injection attacks. Since all existing attacks are ad-hoc in that they target individual parameters of specific signature schemes, it remains unclear about the impact of Rowhammer on signature schemes as a whole. In this paper, we present Achilles, a formal framework that aids in leaking secrets in various real-world signature schemes via Rowhammer. Particularly, Achilles can be used to find potentially more vulnerable parameters in schemes that have been studied before and also new schemes that are potentially vulnerable. Achilles mainly describes a formal procedure where Rowhammer faults are induced to key parameters of a generalized signature scheme, called G-sign, and a post-Rowhammer analysis is then performed for secret recovery on it. To illustrate the viability of Achilles, we have evaluated six signature schemes (with five CVEs assigned to track their respective Rowhammer vulnerability), covering traditional and post-quantum signatures with different mathematical problems. Based on the analysis with Achilles, all six schemes are proved to be vulnerable, and two new vulnerable parameters are identified for EdDSA. Further, we demonstrate a successful Rowhammer attack against each of these schemes, using recent cryptographic libraries including wolfsslrelic, and liboqs.
Zhang H. The Acquisition of Chinese Pinyin and Hanzi: A study from English and Arabic learners. Routledge; 2025. 访问链接
Activation of Chlorite with Sunlight for the Efficient Disinfection of Antibiotic-Resistant Bacteria: the Overlooked Contribution of Cytomembrane-Bound Chlorite
Shen Y, Liu F, Liang J, Li Z, Hou Y, Wu J, Ting Y, Guo R, Liu Y, Han P, et al. Activation of Chlorite with Sunlight for the Efficient Disinfection of Antibiotic-Resistant Bacteria: the Overlooked Contribution of Cytomembrane-Bound Chlorite. Environmental Science & Technology [Internet]. 2025;59:19526-19536. 访问链接Abstract
Current antibiotic-resistant bacteria (ARB) disinfection techniques commonly rely on large dosages of oxidants, resulting in the presence of considerable amounts of residuals and toxic disinfection byproducts (DBPs) in water. Herein, we propose a highly effective ARB disinfection approach via activating an ultralow concentration (10 μM) of chlorite (ClO2–) by naturally abundant sunlight to generate various reactive species (i.e., HO•, Cl•, ClO•, and ClO2) with negligible generation of halogenated DBPs. Combining in situ characterization with theoretical calculations, we reveal that, in addition to the photolysis of ClO2– in the bulk solution, ClO2– ions electrostatically adsorbed on the positive local sites of lipids can boost light absorption and facilitate the in situ generation of reactive species upon sunlight irradiation, enabling more efficient attacks toward cell membranes and the intracellular antioxidant enzyme system. The intracellular antibiotic resistance genes (ARGs) are then released and further degraded, inhibiting horizontal ARG transfer. This approach can also achieve excellent ARB disinfection performance in real water matrices (e.g., lake and river water) in 1 L tanks and 500 mL plastic bottles with natural sunlight irradiation. Overall, this work presents an efficient, safe, and sustainable method to inactivate ARB with deep insights into disinfection mechanisms at the subcellular level.
Guo H, Sun T, Liu H, Wu Z. Adaptive Ensemble Learning With Category-Aware Attention and Local Contrastive Loss. IEEE Transactions on Circuits and Systems for Video Technology [Internet]. 2025;35:1224–1236. 访问链接
Deng Y, Shao S, Mogilner A, Xia M. Adaptive hyperbolic-cross-space mapped Jacobi method on unbounded domains with applications to solving multidimensional spatiotemporal integrodifferential equations. Journal of Computational Physics [Internet]. 2025;520:113492. 访问链接Abstract
In this paper, we develop a new adaptive hyperbolic-cross-space mapped Jacobi (AHMJ) method for solving multidimensional spatiotemporal integrodifferential equations in unbounded domains. By devising adaptive techniques for sparse mapped Jacobi spectral expansions defined in a hyperbolic cross space, our proposed AHMJ method can efficiently solve various spatiotemporal integrodifferential equations such as the anomalous diffusion model with reduced numbers of basis functions. Our analysis of the AHMJ method gives a uniform upper error bound for solving a class of spatiotemporal integrodifferential equations, leading to effective error control.
Zhong Y, Zhao X, Zhang L, Song X, Jiang T. Adaptive Prompt Learning for Blind Image Quality Assessment with Multi-modal Mixed-datasets Training, in Proceedings of the 33rd ACM International Conference on Multimedia. Dublin, Ireland; 2025:7453-7462. 访问链接Abstract
Due to the high cost and small scale of Image Quality Assessment (IQA) datasets, achieving robust generalization remains challenging for prevalent Blind IQA (BIQA) methods. Traditional deep learning-based methods emphasize visual information to capture quality features, while recent developments in Vision-Language Models (VLMs) demonstrate strong potential in learning generalizable representations through textual information. However, applying VLMs to BIQA poses three major Challenges: (1) How to make full use of the multi-modal information. (2) The prompt engineering for appropriate quality description is extremely time-consuming. (3) How to use mixed data for joint training to enhance the generalization of VLM-based BIQA model. To this end, we propose a Multi-modal BIQA method with prompt learning, named MMP-IQA. For (1), we propose a conditional fusion module to better utilize the cross-modality information. By jointly adjusting visual and textual features, our model can capture quality information with a stronger representation ability. For (2), we model the quality prompt's context words with learnable vectors during the training process, which can be adaptively updated for superior performances. For (3), we jointly train a linearity-induced quality evaluator, a relative quality evaluator, and a dataset-specific absolute quality evaluator. In addition, we propose a dual automatic weight adjustment strategy to adaptively balance the loss weights between different datasets and among various losses within the same dataset. Extensive experiments illustrate the superior effectiveness of MMP-IQA.
Guo X, Yu W, Li X, Wang H, Liu Q, Zou Y, Gao Y, Chen Z, Xiao L, Qu B. Ag management of rudorffites solar cells utilizing aliphatic ammonium. MATERIALS FUTURES. 2025;4.

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