Abstract Accelerated glacier-snow-permafrost erosion due to global warming amplifies the sediment availability in cold environments and affects the time-varying suspended sediment concentration (SSC) and discharge (Q) relationship. Here, the sediment-availability-transport (SAT) model is proposed to simulate dynamic SSC-Q relationships by integrating the sediment availability coupled by thermal processes, fluvial processes and long-term storage exhaustion into a sediment rating curve (SSC = a ? Qb with a and b as fitting parameters). In the SAT-model, increased sediment sources from glacier-snow-permafrost erosion are captured by changes in basin temperature, showing an exponential amplification of SSC when basin temperature increases. Enhanced fluvial erosion by the elevated water supply from rainfall and meltwater is captured by the factor of runoff surge, which results in a linear amplification of SSC. The SAT-model is validated for the permafrost-dominated Tuotuohe basin on Tibetan Plateau utilizing multi-decadal daily SSC/Q in-situ observations (1985?2017). Results show that sediment rating curves for Tuotuohe display significant inter-annual variations. The higher parameter-b in a warmer and wetter climate confirms the increased sediment availability due to the expanded erodible landscapes and gullying-enhanced connectivity between channels and slopes. Through capturing such time-varying sediment availability, the SAT-model can robustly reproduce the long-term evolution, seasonality, and various event-scale hysteresis of SSC, including clockwise, counter-clockwise, figure-eight, counter-figure-eight, and more complex hysteresis loops. Overall, the SAT-model can explain over 75% of long-term SSC variance with stable performance under hydroclimate abrupt changes, outperforming the conventional and static sediment rating curve approach by 20%. The SAT-model not only advances understanding of sediment transport mechanisms by integrating thermal- and fluvial-erosion processes, but also provides a model framework to simulate and project future sediment loads in other cold basins.
Iron hydroxides are important scavengers for dissolved chromium (Cr) via coprecipitation processes; however, the influences of organic matter (OM) on Cr sequestration in Fe/Cr-OM ternary systems and the stability of the coprecipitates are not well understood. Here, Fe/Cr-OM coprecipitation was conducted at pH 3, and Cr hydroxide was undersaturated. Acetic acid (HAc), poly(acrylic acid) (PAA), and Suwannee River natural organic matter (SRNOM) were selected as model OMs, which showed different complexation capabilities with Fe/Cr ions and Fe/Cr hydroxide particles. HAc had no significant effect on the coprecipitation, as the monodentate carboxyl ligand in HAc did not favor complexation with dissolved Fe/Cr ions or Fe/Cr hydroxide nanoparticles. Contrarily, PAA and SRNOM with polydentate carboxyl ligand had strong complexation with Fe/Cr ions and Fe/Cr hydroxide nanoparticles, leading to significant amounts of PAA/SRNOM sequestered in the coprecipitates, which caused the structural disorder and fast aggregation of the coprecipitates. In comparison with that of PAA, preferential complexation of Cr ions with SRNOM resulted in higher Cr/Fe ratios in the coprecipitates. This study advances the fundamental understanding of Fe/Cr-OM coprecipitation and mechanisms controlling the composition and stability of the coprecipitates, which is essential for successful Cr remediation and removal in both natural and engineered settings.
Despite the increasing usage of porphyrinic metal-organic frameworks (MOFs) for combination therapy, the controlled encapsulation of inorganic nanoparticle-based therapeutics into such MOFs with specific structures has remained a major obstacle for improved tumor therapy. Here, we report the synthesis of a mesoporous MOF shell on the surface of gold nanorods (AuNRs), wherein a single AuNR is captured individually in single-crystalline MOFs with a controlled crystallographic orientation, for combinational phototherapy against solid tumors. The core-shell heterostructures have the benefits of a mesoporous structure and photoinduced singlet oxygen generation behavior characterized by the porphyrinic MOF shell, together with the plasmonic photothermal conversion characteristic of AuNRs. We demonstrated that the AuNR@MOF nanoplatform enables an efficient tumor treatment strategy by combining photodynamic therapy and photothermal therapy. We should emphasize that such systems could have applications beyond the field of cancer therapy, like plasmonic harvesting of light energy to induce and accelerate catalytic reactions within MOFs and multifunctional nanocarriers for agricultural formulations.
Peroxymonosulfate (PMS)-based advanced oxidation processes (PMS-AOPs) as an efficient strategy for organic degradation are highly dependent on catalyst design and structured active sites. However, the identification of the active sites and their relationship with reaction mechanisms for organic degradation are not fully understood for a composite catalyst due to the complex structure. Herein, we developed a family of Co encapsulated in N-doped carbons (Co-PCN) with tailored types and contents of active sites via manipulated pyrolysis for PMS activation and ciprofloxacin (CIP) degradation, focusing on the correlation of active sites to generated reactive species and degradation routes of organics. The structure–function relationships between the different active sites in Co-PCN catalysts and reactive oxygen species (ROS), as well as bond breaking position of CIP, were revealed through regression analysis and density functional theory calculation. Co–Nx, O–C═O, C═O, graphitic N, and defects in Co-PCN stimulate the generation of 1O2 for oxidizing the C–C bond in the piperazine ring of CIP into C═O. The substitution of F by OH and hydroxylation of the piperazine ring might be induced by SO4•– and •OH, whose formation was affected by C–O, Co(0), Co–Nx, graphitic N, and defects. The findings provided new insights into reaction mechanisms in PMS-AOP systems and rational design of catalysts for ROS-oriented degradation of pollutants.
This paper examines a Sinopean victory list of the boxer Marcus Iutius Marcianus Rufus (French 2004: 76-77 no. 105) and the implications of counting the number of victories he won. Inscribed and set up by the Sinopean boule, the list represents an official recognition of the athlete's successful boxing career, which not only included victories in the four periodoi of mainland Greece, but also the Capitoline and Neapolitan games in Italy. The text has been studied by Theodoré Reinach (1916), George Bean (1953), and David French (2004), and resulting in different ways to count Rufus' victories.The three epigraphists encountered several issues with counting Rufus' victories. How to differentiate between a Bithynian koinon event from a metropolitan event held by Nicaea and Nicomedia is one issue, and whether to count the half-talent victories with the iselastic victories so to fit an ideal number of total victories that Rufus won is another, with the three epigraphists producing different solutions. Perhaps more perplexing of all, however, is how to interpret the Greek letters ΡΝ placed at the end of the victory list. Reinach interpreted them as the remaining letters of ἀνδριατί or "jeux mineurs" (Reinach 1916: 358). Bean and French saw them as Greek numerals, indicating the total tally of all listed victories. While the total tally seems a convincing interpretation on formulaic grounds, the arithmetic does not add up. On the one hand, tabulation indicates that Bean's count of total victories yields 159, with 110 half-talent victories and 49 iselastic victories. He reconciled the number by claiming to have seen signs of reinscribing in the squeeze, and suggested that Rufus initially won 101 half-talent victories, only to have achieved 110 at a later time, upon which occasion an update was applied to his monument (Bean 1953: 176). On the other hand, while French counted the half-talent victories as 110, and his total number of iselastic victories amount to 48, he still maintained that ΡΝ stands for "(In all) 150 victories," leaving the arithmetic issue open for further examination (French 2004: 77).This paper surveys other victory lists to study how koinon and metropolitan victories were differentiated and counted, and how chronographic features were positioned and identified. This paper also proposes to disassociate the number 150 from the total count of victories, and reconsider what was signified by this number. One possibility is the era: the 150th year of the era of Sinope. It has been demonstrated that Sinopean coinage during the imperial period used first the colonial era from 45 BCE, then the so-called Lucullan era of 70 BCE (Leschhorn 1993: 161-162). While era-based chronography is not found on extant imperial period inscriptions from Sinope, Rufus' victory list may be the first surviving example.
A uniform statistical inferential tool in making individualized treatment decisions, which implements the methods of Ma et al. (2017)<doi:10.1177/0962280214541724> and Guo et al. (2021)<doi:10.1080/01621459.2020.1865167>. It uses a flexible semiparametric modeling strategy for heterogeneous treatment effect estimation in high-dimensional settings and can gave valid confidence bands. Based on it, one can find the subgroups of patients that benefit from each treatment, thereby making individualized treatment selection.
The purpose of this study was to examine the daily social pressure and socioeconomic factors related to women’s alcohol consumption in China. Cross-sectional data were obtained from the 2012 China Family Panel Studies. A multivariate logistic regression analysis of a sample of 16 339 female adults with the mean age of 45.3 years was used to examine the relationships between dependent and independent variables. According to the results, first, the greater the daily social pressure, the more likely women were to engage in general alcohol consumption (odds ratio = 1.061) and risk drinking (odds ratio = 1.057). Second, while there is a positive relationship between the general level of social pressure and women’s alcohol consumption, the relationship between the severe level of social pressure and women’s alcohol consumption was not significant. Finally, women in the Central region were less likely to engage in risk drinking than women in the Western region; women with secondary school education were more likely to engage in risk drinking than women with primary school education or below; and age was significantly positively associated with both general and risk drinking. In conclusion, increasing alcohol consumption among women may be due to increased social pressure.
