科研成果

2009
Yao M, Zhu T, Li K, Dong S, Wu Y, Qiu X, Jiang B, Chen L, Zhen S. Onsite infectious agents and toxins monitoring in 12 May Sichuan earthquake affected areas. Journal of Environmental Monitoring. 2009;11:1993-2001.Abstract
At 14: 28 on 12 May 2008, Sichuan Province of China suffered a devastating earthquake measuring 8.0 on the Richter scale with more than 80 000 human lives lost and millions displaced. With inadequate shelter, poor access to health services, and disrupted ecology, the survivors were at enormous risk of infectious disease outbreaks. This work, believed to be unprecedented, was carried out to contain a possible outbreak through onsite monitoring of airborne biological agents in the high-risk areas. In such a mission, a mobile laboratory was developed using a customized vehicle along with state-of-art bioaerosol and molecular equipment and tools, and deployed to Sichuan 11 days after the earthquake. Using a high volume bioaerosol sampler (RCS High Flow) and Button Inhalable Aerosol Sampler equipped with gelatin filters, a total of 55 air samples, among which are 28 filter samples, were collected from rubble, medical centers, and camps of refugees, troops and rescue workers between 23 May and 9 June, 2008. After pre-treatment of the air samples, quantitative polymerase chain reaction (qPCR), gel electrophoresis, limulus amebocyte lysate (LAL) assay and enzyme-linked immunosorbent assay (ELISA) were applied to detect infectious agents and to quantify environmental toxins and allergens. The results revealed that, while high levels of endotoxin (180 similar to 975 ng/m(3)) and (1,3)-beta-D-glucans (11 similar to 100 ng/m(3)) were observed, infectious agents such as Bacillus anthracis, Bordetella pertussis, Neisseria meningitidis, Mycobacterium tuberculosis, influenza A virus, bird flu virus (H5N1), enteric viruses, and Meningococcal meningitis were found below their detection limits. The total bacterial concentrations were found to range from 250 to 2.5 x 10(5) DNA copies/L. Aspergillus fumigatus (Asp f 1) and dust mite allergens (Der p 1 and Der f 1) were also found below their detection limits.
李广建, 李亚子, 蒋君. OPENURL标准的版本演化及比较分析. 图书馆杂志. 2009;(7):53-59.Abstract
首先简要介绍OPENURL,分析OPENURL0.1版本的不足,以及OPENURL0.1到OPENURL1.0的演变过程,对各个版本进行了对比,详细介绍了OPENURL1.0中的各个实体以及NAMESPACES、CHARACTER ENCODINGS、SERIALIZATIONS等8个核心组件,通过KEV CONTEXTOBJECT以及XML CONTEXTOBJECT两种描述方式实例解释这8个组件在实际中的应用.
Liu Y, Yu Y, Guo H, Yang P. Optimal Land-Use Management for Surface Source Water Protection Under Uncertainty: A Case Study of Songhuaba Watershed (Southwestern China). WATER RESOURCES MANAGEMENT. 2009;23:2069-2083.Abstract
The water supply to Chinese cities is increasingly degrading from pollution due to watershed activities. Consequently, water source protection requires urgent action using optimal land-use management efforts. An inexact linear programming model for optimal land-use management of surface water source area was developed. The model was proposed to balance the economic benefits of land-use development and water source protection. The maximum net economic benefit (NEB) was chosen as the objective of land-use management. The total environmental capacity (TEC) of rivers and the minimum water supply (MWS) were considered key constraints. Other constraints included forest coverage, government requirements concerning the proportions of various land-use types, soil loss, slope lands, and technical constraints. A case study was conducted for the Songhuaba Watershed, a reservoir supplying water to Kunming City, the third largest city in southwestern China. A 15-year (2006 to 2020) optimal model for land-use management was developed to better protect this water source and to gain maximum benefits from development. Ten constraints were involved in the optimal model, and results indicated that NEB ranged between 893 and 1,459 million US\$. The proposed model will allow local authorities to better understand and address complex land-use systems and to develop optimal land-use management strategies for balancing source water protection and local economic development.
Guo D, Xue M, Guo Q, Wu K, Guo J, Wang EG. Ordered ultra thin ZnO films on metal substrate. Applied Surface Science. 2009;(22):9015-9019.
Landrock S, Jiang Y, Wu KH, Wang EG, Urban K, Ebert P. Origin of nanoscale potential fluctuations in two-dimensional semiconductors. Applied Physics Letters. 2009;(7).
Landrock S, Jiang Y, Wu KH, Wang EG, Urban K, Ebert P. Origin of nanoscale potential fluctuations in two-dimensional semiconductors. 2009;(7).
Guan H, Kang D, Fan M, Chen Z, Qu L-J. Overexpression of a new putative membrane protein gene AtMRB1 results in organ size enlargement in Arabidopsis. Journal of Integrative Plant Biology [Internet]. 2009;(2):130-139. 访问链接
Wang S, Publicover S, Gu Y. An oxygen-sensitive mechanism in regulation of epithelial sodium channel. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2009;(8):2957-2962. 访问链接
Yang J, Zhang W, Jiang W, Sun X, Han Y, Ding M, Shi Y, Deng H. P21cip-overexpression in the mouse β cells leads to the improved recovery from streptozotocin-induced diabetes. PLoS ONE [Internet]. 2009;(12). 访问链接
Liu X-X, Rocchi P, Qu F-Q, Zheng S-Q, Liang Z-C, Gleave M, Iovanna J, Peng L. PAMAM dendrimers mediate siRNA delivery to target Hsp27 and produce potent antiproliferative effects on prostate cancer cells. ChemMedChem [Internet]. 2009;(8):1302-1310. 访问链接
Yin P-F, Yuan Q, Liu J, Zhang J, Bi X-J, Zhu S-hua. PAMELA data and leptonically decaying dark matter. Phys. Rev. D. 2009;79:023512.
Tong Z, Fan Y, Zhang W, Xu J, Cheng J, Ding M, Deng H. Pancreas-specific pten deficiency causes partial resistance to diabetes and elevated hepatic AKT signaling. Cell Research [Internet]. 2009;(6):710-719. 访问链接
Hu M, Guo S. Particle pollution in Beijing: features, source and secondary formation. IGAC Newsletter. 2009;42:10-18.
Hu M, Guo S. Particle pollution in Beijing: features, source and secondary formation. IGAC Newsletter. 2009;42:10-18.
Hu M, Guo S. Particle pollution in Beijing: features, source and secondary formation. IGAC Newsletter. 2009;42:10-18.
Zheng H, Wang F, Xu J, Zhou N, Qian M, Zhu J, Deng M. Pathway detection based on hierarchical LASSO regression model. Proceedings of the 2009 2nd International Conference on Biomedical Engineering and Informatics, BMEI 2009. 2009.
Yuan X-J, Shao X, Liao H-M, Ouyang Q. Pattern formation in the turing-Hopf codimension-2 phase space in a reaction-diffusion system. Chinese Physics Letters. 2009;(2).
樊春. PBS 在北京大学的使用经验. 中山大学学报: 自然科学版. 2009:347–349.
You F, Sun H, Zhou X, Sun W, Liang S, Zhai Z, Jiang ZF. PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. Nature Immunology [Internet]. 2009;(12):1300-1308. 访问链接
Lu Z-L, Yu C, Watanabe T, Sagi D, Levi D. Perceptual learning: Functions, mechanisms, and applications. Vision Research [Internet]. 2009;(21):2531-2534. 访问链接

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