科研成果

2014
Zhu X, Ge X, Li N, Wu L-F, Luo C, Ouyang Q, Tu Y, Chen G. Angle sensing in magnetotaxis of Magnetospirillum magneticum AMB-1. Integrative Biology (United Kingdom). 2014;(7):706-713.
Zhu X, Ge X, Li N, Wu L-F, Luo C, Ouyang Q, Tu Y, Chen G. Angle sensing in magnetotaxis of Magnetospirillum magneticum AMB-1. Integrative Biology (United Kingdom). 2014;(7):706-713.
Zhu X, Ge X, Li N, Wu L-F, Luo C, Ouyang Q, Tu Y, Chen G. Angle sensing in magnetotaxis of Magnetospirillum magneticum AMB-1. Integrative Biology (United Kingdom). 2014;(7):706-713.
Zhang L, Niu Q. Angular momentum of phonons and the Einstein-de Haas effect. Physical Review Letters. 2014;(8).
Chen H, Niu Q, MacDonald AH. Anomalous hall effect arising from noncollinear antiferromagnetism. Physical Review Letters. 2014;(1).
Guo GY, Niu Q, Nagaosa N. Anomalous Nernst and Hall effects in magnetized platinum and palladium. Physical Review B - Condensed Matter and Materials Physics. 2014;(21).
Xia S, Zhao Q, Li B, Shen G. Anthropogenic Source VOCs Emission Inventory of Jiangsu Province. Research of Environmental Sciences [Internet]. 2014;27:120-126. 访问链接
Fu H, Yan C, Zheng M*, Cai J, Li X, Zhang Y, ZHOU Z, Fu Z, Li M, Li L, et al. Application of on-line single particle aerosol mass spectrometry (SPAMS) for studying major components in fine particulate matter. Environmental Science [Internet]. 2014;35:4070—4077. LINK
Yang Y, Ou B, Zhang J, Si W, Gu H, Qin G, Qu L-J. The Arabidopsis Mediator subunit MED16 regulates iron homeostasis by associating with EIN3/EIL1 through subunit MED25. Plant Journal. 2014;(6):838-851.
Zhang X, Xiong R, Ma S, Gao W. Artifact reduction of compressed video via three-dimensional adaptive estimation of transform coefficients, in 2014 IEEE International Conference on Image Processing, ICIP 2014, Paris, France, October 27-30, 2014.; 2014:4567–4571. 访问链接
Boyle CE, Huang Q, Wang J. Assessing the impacts of fiscal reforms on investment in village-level irrigation infrastructure. Water Resources Research. 2014;50:6428–6446.
Zhu Y, Liu K, Tang X, Wang J, Yu Z, Wu Y, Chen D, Wang X, Fang K, Li N, et al. Association between NINJ2 gene polymorphisms and ischemic stroke: a family-based case-control study. Journal of Thrombosis and Thrombolysis. 2014;38:470-6.Abstract
Novel susceptibility genes related to ischemic stroke (IS) are proposed in recent literatures. Population-based replicate studies would cause false positive results due to population stratification. 229 recruit IS patients and their 229 non-IS siblings were used in this study to avoid population stratification. The family-based study was conducted in Beijing from June 2005 to June 2012. Association between SNPs and IS was found in the sibship discordant tests, and the conditional logistic regression was performed to identify effect size and explore gene-environment interactions. Significant allelic association was identified between NINJ2 gene rs11833579 (P = 0.008), protein kinase C eta gene rs2230501 (P = 0.039) and IS. The AA genotype of rs11833579 increased 1.51-fold risk (95% CI 1.04-3.46; P = 0.043) of IS, and it conferred susceptibility to IS only in a dominant model (OR 2.69; 95% CI 1.06-6.78; P = 0.036]. Risk of IS was higher (HR 3.58; 95% CI 1.54-8.31; P = 0.003) especially when the carriers of rs11833579 AA genotype were smokers. The present study suggests A allele of rs11833579 may play a role in mediating susceptibility to IS and it may increase the risk of IS together with smoking.
Zhu Y, Liu K, Tang X, Wang J, Yu Z, Wu Y, Chen D, Wang X, Fang K, Li N, et al. Association between NINJ2 gene polymorphisms and ischemic stroke: a family-based case-control study. J Thromb Thrombolysis. 2014;38(4):470-6.Abstract
Novel susceptibility genes related to ischemic stroke (IS) are proposed in recent literatures. Population-based replicate studies would cause false positive results due to population stratification. 229 recruit IS patients and their 229 non-IS siblings were used in this study to avoid population stratification. The family-based study was conducted in Beijing from June 2005 to June 2012. Association between SNPs and IS was found in the sibship discordant tests, and the conditional logistic regression was performed to identify effect size and explore gene-environment interactions. Significant allelic association was identified between NINJ2 gene rs11833579 (P = 0.008), protein kinase C η gene rs2230501 (P = 0.039) and IS. The AA genotype of rs11833579 increased 1.51-fold risk (95% CI 1.04-3.46; P = 0.043) of IS, and it conferred susceptibility to IS only in a dominant model (OR 2.69; 95% CI 1.06-6.78; P = 0.036]. Risk of IS was higher (HR 3.58; 95% CI 1.54-8.31; P = 0.003) especially when the carriers of rs11833579 AA genotype were smokers. The present study suggests A allele of rs11833579 may play a role in mediating susceptibility to IS and it may increase the risk of IS together with smoking.
Li J, Gao X, Luo T, Wu J, Sun G, Liu Q, Jiang Y, Zhang Y, Mei J, Gao Q. Association of gyrA/B mutations and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis. Emerg Microbes Infect [Internet]. 2014;3:e19. 访问链接Abstract
To evaluate the association between mutations in the genes gyrA/B and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis, a total of 80 ofloxacin-resistant isolates collected in 2009 by the Shanghai Municipal Centers for Disease Control and Prevention were studied. The minimum inhibitory concentration (MIC) of ofloxacin, moxifloxacin and gatifloxacin for each isolate was determined using the microscopic observation drug susceptibility assay. Sequencing was used to identify mutations in the quinolone resistance-determining region (QRDR) of the gyrA and gyrB genes. In total, 68 isolates had mutations in gyrA, three isolates had mutations in gyrB, six isolates had mutations in both gyrA and gyrB, and three isolates had no mutations. Two common mutations in gyrA, the D94G and D94N mutations, were associated with higher-level resistance to all three fluoroquinolones than two other common mutations (A90V and D94A). Understanding the relationship between MICs and mutations in ofloxacin-resistant isolates will facilitate the optimization of the use of new-generation fluoroquinolones to treat patients with ofloxacin-resistant tuberculosis (TB).
Yadav J, Stanton GR, Fan XY, Robinson JR, Schelter EJ, Walsh PJ, Pericas MA. Asymmetric Allylation of Ketones and Subsequent Tandem Reactions Catalyzed by a Novel Polymer-Supported Titanium-BINOLate Complex. Chemistry-a European JournalChemistry-a European Journal. 2014;20:7122-7127.Abstract
By using a novel, simple, and convenient synthetic route, enantiopure 6-ethynyl-BINOL (BINOL=1,1-binaphthol) was synthesized and anchored to an azidomethylpolystyrene resin through a copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction. The polystyrene (PS)-supported BINOL ligand was converted into its diisopropoxytitanium derivative in situ and used as a heterogeneous catalyst in the asymmetric allylation of ketones. The catalyst showed good activity and excellent enantioselectivity, typically matching the results obtained in the corresponding homogeneous reaction. The allylation reaction mixture could be submitted to epoxidation by simple treatment with tert-butyl hydroperoxide (TBHP), and the tandem asymmetric allylation epoxidation process led to a highly enantioenriched epoxy alcohol with two adjacent quaternary centers as a single diastereomer. A tandem asymmetric allylation/Pauson-Khand reaction was also performed, involving simple treatment of the allylation reaction mixture with Co2(CO)8/N-methyl morpholine N-oxide. This cascade process resulted in the formation of two diastereomeric tricyclic enones in high yields and enantioselectivities.
Nehr S, Bohn B, Dorn H-P, Fuchs H, Häseler R, Hofzumahaus A, Li X, Rohrer F, Tillmann R, Wahner A. Atmospheric photochemistry of aromatic hydrocarbons: OH budgets during SAPHIR chamber experiments. Atmospheric Chemistry and Physics. 2014;14(13):6941-6952.Abstract
Current photochemical models developed to simulate the atmospheric degradation of aromatic hydrocarbons tend to underestimate OH radical concentrations. In order to analyse OH budgets, we performed experiments with benzene, toluene, p-xylene and 1,3,5-trimethylbenzene in the atmosphere simulation chamber SAPHIR. Experiments were conducted under low-NO conditions (typically 0.1–0.2 ppb) and high-NO conditions (typically 7–8 ppb), and starting concentrations of 6–250 ppb of aromatics, dependent on OH rate constants. For the OH budget analysis a steady-state approach was applied in which OH production and destruction rates (POH and DOH) have to be equal. The POH were determined from measurements of HO2, NO, HONO, and O3 concentrations, considering OH formation by photolysis and recycling from HO2. The DOH were calculated from measurements of the OH concentrations and total OH reactivities. The OH budgets were determined from DOH/POH ratios. The accuracy and reproducibility of the approach were assessed in several experiments using CO as a reference compound where an average ratio DOH/POH = 1.13 ± 0.19 was obtained. In experiments with aromatics, these ratios ranged within 1.1–1.6 under low-NO conditions and 0.9–1.2 under high-NO conditions. The results indicate that OH budgets during photo-oxidation experiments with aromatics are balanced within experimental accuracies. Inclusion of a further, recently proposed OH production via HO2 + RO2 reactions led to improvements under low-NO conditions but the differences were small and insignificant within the experimental errors.
Li W, Wang C, Wang H, Chen J, Shen H, Shen G, Huang Y, Wang R, Wang B, Zhang Y, et al. Atmospheric polycyclic aromatic hydrocarbons in rural and urban areas of northern China. Environmental Pollution [Internet]. 2014;192:83-90. 访问链接
Ma D*, Yang F*. Authoritarian Orientations and Political Trust in East Asian Societies. East Asia. 2014;34(4):323-41.
Zheng Z, Li J, Li J, Tan Y. Avoiding decoys in multiple targets searching problems using swarm robotics, in 2014 IEEE Congress on Evolutionary Computation (CEC). IEEE; 2014:784–791. 访问链接
He Z, Yu L, Zheng X, Ma S. AVS2-video coding standard - An application-oriented and high perforamce video coding standard, in 2013 IEEE International Conference on Multimedia and Expo Workshops, Chengdu, China, July 14-18, 2014.; 2014:1–5. 访问链接

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