Citation:
Jiang, X. ; Zhu, N. ; Zhao, D. *; Ma, Y. *. New Cyclometalated Transition-Metal Based Photosensitizers for Singlet Oxygen Generation and Photodynamic Therapy. Sci. China. Chem. 2016, 59, 40-52.
摘要:
The aim of this review article is to introduce recent studies on an emergent class of singlet oxygen photosensitizers of potential applications to the photodynamic therapy, with a primary focus on the cyclometalated transition-metal complexes. Singlet oxygen photosensitization performances of various cyclometalated Ir and Pt scaffolds are reviewed, and the general photo-physical properties of relevant systems and the mechanisms of singlet oxygen production via photo-sensitization are also briefly discussed. Thus far, investigations of singlet oxygen sensitization by such Ir and Pt complexes are mainly carried out in organic solvents and under non-physiological conditions, while some research efforts have been made at examining the feasibility of applying pertinent cyclometalated complexes to photodynamic therapy.See also: 2016