科研成果

1997
Nicolaou KC, Yang Z, Ouellette M, Shi G-Q, Gartner P, Gunzner JL, Agrios KA, Huber R, Chadha R, Huang DH. New synthetic technology for the construction of 9-membered ring cyclic ethers. Construction of the EFGH ring skeleton of brevetoxin A. Journal of the American Chemical Society. 1997;(34):8105-8106.
Nicolaou KC, Shi G-Q, Gunzner JL, Gartner P, Yang Z. Palladium-catalyzed functionalization of lactones via their cyclic ketene acetal phosphates. Efficient new synthetic technology for the construction of medium and large cyclic ethers [12]. Journal of the American Chemical Society. 1997;(23):5467-5468.
Nicolaou KC, Sarabia F, Ninkovic S, Yang Z. Total Synthesis of Epothilone A: The Macrolactonization Approach. Angewandte Chemie (International Edition in English). 1997;(5):525-526.
Yang Z, He Y, Vourloumis D, Vallberg H, Nicolau KC. Total synthesis of epothilone A: The olefin metathesis approach. Angewandte Chemie - International Edition in English. 1997;(1-2):166-168.
Nicolaou KC, He Y, Vourloumis D, Vallberg H, Roschangar F, Sarabia F, Ninkovic S, Yang Z, Trujillo JI. The olefin metathesis approach to epothilone A and its analogues. Journal of the American Chemical Society. 1997;(34):7960-7973.
Nicolaou KC, Ninkovic S, Sarabia F, Vourloumis D, He Y, Vallberg H, Finlay MRV, Yang Z. Total syntheses of epothilones A and B via a macrolactonization-based strategy. Journal of the American Chemical Society. 1997;(34):7974-7991.
Nicolaou KC, Winssinger N, Pastor J, Ninkovic S, Sarabia F, He Y, Vourloumis D, Yang Z, Li T, Giannakakou P, et al. Synthesis of epothilones A and B in solid and solution phase. Nature [Internet]. 1997;(6630):268-272. 访问链接 SCI被引用次数:352.
1996
Nicolaou KC, He Y, Vourloumis D, Vallberg H, Yang Z. An approach to epothilones based on olefin metathesis. Angewandte Chemie (International Edition in English). 1996;(20):2399-2401.
1995
Johnson CR, Xu Y, Nicolaou KC, Yang Z, Guy RK, Dong JG, Berova N. Enzymatic resolution of a key stereochemical intermediate for the synthesis of (-)-taxol. Tetrahedron Letters. 1995;(19):3291-3294.
Nicolaou KC, Liu J-J, Yang Z, Ueno H, Sorensen EJ, Claiborne CF, Guy RK, Hwang C-K, Nakada M, Nantermet PG. Erratum: Total synthesis of taxol. 2. Construction of A and C ring intermediates and initial attempts to construct the ABC ring system (J. Am. Chem. Soc. 1995, 117, 634-644). Journal of the American Chemical Society. 1995;(33):8690-.
Nicolaou KC, Theodorakis EA, Rutjes FPJT, Sato M, Tiebes J, Xiao X-Y, Hwang C-K, Duggan ME, Yang Z, Couladouros EA, et al. Total synthesis of brevetoxin B. 2. Second generation strategies and construction of the dioxepane region [DEFG]. Journal of the American Chemical Society. 1995;(41):10239-10251.
Nicolaou KC, Liu J-J, Yang Z, Ueno H, Sorensen EJ, Claiborne CF, Guy RK, Hwang C-K, Nakada M, Nantermet PG. Total synthesis of Taxol. 2. Construction of A and C ring intermediates and initial attempts to construct the ABC ring system. Journal of the American Chemical Society. 1995;(2):634-644. SCI被引用次数:227.
Nicolaou KC, Yang Z, Liu J-J, Nantermet PG, Claiborne CF, Renaud J, Guy RK, Shibayama K. Total synthesis of Taxol. 3. Formation of Taxol's ABC ring skeleton. Journal of the American Chemical Society. 1995;(2):645-652. SCI被引用次数:167.
Nicolaou KC, Ueno H, Liu J-J, Nantermet PG, Yang Z, Renaud J, Paulvannan K, Chadha R. Total synthesis of Taxol. 4. The final stages and completion of the synthesis. Journal of the American Chemical Society. 1995;(2):653-659. SCI被引用次数:193.
1994
Nicolaou KC, Nadin A, Leresche JE, Greca SL, Tsuri T, Yue EW, Yang Z. Synthesis of the first fully functionalized core of the zaragozic acids/squalestatins. Angewandte Chemie (International Edition in English). 1994;(21):2187-2190.
Nicolaou KC, Yue EW, Naniwa Y, Riccardis FD, Nadin A, Leresche JE, Greca SL, Yang Z. Zaragozic acid A/squalestatin S1: Synthetic and retrosynthetic studies. Angewandte Chemie (International Edition in English). 1994;(21):2184-2187.
Nicolaou KC, Yang Z, Liu JJ, Ueno H, Nantermet PG, Guy RK, Claiborne CF, Renaud J, Couladouros EA, Paulvannan K, et al. Total synthesis of taxol. Nature [Internet]. 1994;(6464):630-634. 访问链接 SCI被引用次数:840.
1993
Nicolaou KC, Yang Z, Sorensen EJ, Nakada M. Synthesis of ABC taxoid ring systems via a convergent strategy. Journal of the Chemical Society, Chemical Communications. 1993;(12):1024-1026.

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