<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">M. Li</style></author><author><style face="normal" font="default" size="100%">Zhao, J.</style></author><author><style face="normal" font="default" size="100%">Chu, H.</style></author><author><style face="normal" font="default" size="100%">Mi, Y.</style></author><author><style face="normal" font="default" size="100%">Z. Zhou</style></author><author><style face="normal" font="default" size="100%">Di, Z.</style></author><author><style face="normal" font="default" size="100%">Zhao, M.</style></author><author><style face="normal" font="default" size="100%">L. Li</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Light-Activated Nanoprobes for Biosensing and Imaging</style></title><secondary-title><style face="normal" font="default" size="100%">Adv MaterAdv Mater</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">*Light</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">bioimaging</style></keyword><keyword><style  face="normal" font="default" size="100%">biosensing</style></keyword><keyword><style  face="normal" font="default" size="100%">Biosensing Techniques/*methods</style></keyword><keyword><style  face="normal" font="default" size="100%">Fluorescent Dyes/*chemistry/metabolism</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">light-activation</style></keyword><keyword><style  face="normal" font="default" size="100%">nanoprobes</style></keyword><keyword><style  face="normal" font="default" size="100%">Optical Imaging/*methods</style></keyword><keyword><style  face="normal" font="default" size="100%">spatiotemporal control</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">45</style></number><edition><style face="normal" font="default" size="100%">2018/10/03</style></edition><volume><style face="normal" font="default" size="100%">31</style></volume><pages><style face="normal" font="default" size="100%">e1804745</style></pages><isbn><style face="normal" font="default" size="100%">1521-4095 (Electronic)0935-9648 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Fluorescent nanoprobes are indispensable tools to monitor and analyze biological species and dynamic biochemical processes in cells and living bodies. Conventional nanoprobes have limitations in obtaining imaging signals with high precision and resolution because of the interference with biological autofluorescence, off-target effects, and lack of spatiotemporal control. As a newly developed paradigm, light-activated nanoprobes, whose imaging and sensing activity can be remotely regulated with light irradiation, show good potential to overcome these limitations. Herein, recent research progress on the design and construction of light-activated nanoprobes to improve bioimaging and sensing performance in complex biological systems is introduced. First, recent innovative strategies and their underlying mechanisms for light-controlled imaging are reviewed, including photoswitchable nanoprobes and phototargeted nanosystems. Subsequently, a short highlight is provided on the development of light-activatable nanoprobes for biosensing, which offer possibilities for the remote control of biorecognition and sensing activity in a precise manner both temporally and spatially. Finally, perspectives and challenges in light-activated nanoprobes are commented.</style></abstract><accession-num><style face="normal" font="default" size="100%">30276873</style></accession-num><notes><style face="normal" font="default" size="100%">Li, MengyuanZhao, JianChu, HongqianMi, YongshengZhou, ZehaoDi, ZhenghanZhao, MeipingLi, Leleeng21822401/NSFC/21771044/NSFC/Young Thousand Talented Program/ReviewGermanyAdv Mater. 2019 Nov;31(45):e1804745. doi: 10.1002/adma.201804745. Epub 2018 Oct 1.</style></notes><auth-address><style face="normal" font="default" size="100%">CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology (NCNST), Beijing, 100190, China.Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.</style></auth-address></record></records></xml>