<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tsuiki, S</style></author><author><style face="normal" font="default" size="100%">Miyagi, T</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Carcinofetal alterations in glucosamine-6-phosphate synthetase.</style></title><secondary-title><style face="normal" font="default" size="100%">Ann N Y Acad Sci</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Ann N Y Acad Sci</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">aging</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Carbohydrate Epimerases</style></keyword><keyword><style  face="normal" font="default" size="100%">DNA</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Fetus</style></keyword><keyword><style  face="normal" font="default" size="100%">Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycoproteins</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrogen-Ion Concentration</style></keyword><keyword><style  face="normal" font="default" size="100%">Isoenzymes</style></keyword><keyword><style  face="normal" font="default" size="100%">kinetics</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver Regeneration</style></keyword><keyword><style  face="normal" font="default" size="100%">Molecular weight</style></keyword><keyword><style  face="normal" font="default" size="100%">Neoplasms, Experimental</style></keyword><keyword><style  face="normal" font="default" size="100%">Organ Specificity</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Subcellular Fractions</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">1975</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1975 Aug 22</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">259</style></volume><pages><style face="normal" font="default" size="100%">298-306</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">The levels of glucosamine-6-phosphate synthetase in various rat tissues including those undergoing differentiation or regeneration revealed that the enzyme is related to tissue proliferation and differentiation. In the liver upon neoplastic transformation, the level of glucosamine 6-phosphate synthetase rises and the liver form of the enzyme having a pI at 5.0 is replaced by a form with a pI of 4.1. Since the latter form has also been found present in whole embryos (12- and 14-day) and brain, the molecular alterations of glucosamine-6-phosphate synthetase in liver neoplasia can be considered to be carcinofetal.</style></abstract><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/947?dopt=Abstract</style></custom1></record></records></xml>