<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Guo, J.</style></author><author><style face="normal" font="default" size="100%">Y. Zhou</style></author><author><style face="normal" font="default" size="100%">Y. Wang</style></author><author><style face="normal" font="default" size="100%">B. Zhang</style></author><author><style face="normal" font="default" size="100%">J. Zhang</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Assessment of internal exposure to methylsiloxanes in children and associated non-dietary exposure risk</style></title><secondary-title><style face="normal" font="default" size="100%">Environment International</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">absorption</style></keyword><keyword><style  face="normal" font="default" size="100%">air pollution</style></keyword><keyword><style  face="normal" font="default" size="100%">ambient air</style></keyword><keyword><style  face="normal" font="default" size="100%">article</style></keyword><keyword><style  face="normal" font="default" size="100%">attention</style></keyword><keyword><style  face="normal" font="default" size="100%">case report</style></keyword><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Child exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">child health</style></keyword><keyword><style  face="normal" font="default" size="100%">China</style></keyword><keyword><style  face="normal" font="default" size="100%">clinical article</style></keyword><keyword><style  face="normal" font="default" size="100%">concentration (composition)</style></keyword><keyword><style  face="normal" font="default" size="100%">dust</style></keyword><keyword><style  face="normal" font="default" size="100%">Dust ingestion</style></keyword><keyword><style  face="normal" font="default" size="100%">environmental exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Exposure dose</style></keyword><keyword><style  face="normal" font="default" size="100%">Exposure pathways</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">groups by age</style></keyword><keyword><style  face="normal" font="default" size="100%">health risk</style></keyword><keyword><style  face="normal" font="default" size="100%">Health risks</style></keyword><keyword><style  face="normal" font="default" size="100%">Housing</style></keyword><keyword><style  face="normal" font="default" size="100%">human</style></keyword><keyword><style  face="normal" font="default" size="100%">human tissue</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Indoor</style></keyword><keyword><style  face="normal" font="default" size="100%">indoor air</style></keyword><keyword><style  face="normal" font="default" size="100%">indoor air pollution</style></keyword><keyword><style  face="normal" font="default" size="100%">Indoor environment</style></keyword><keyword><style  face="normal" font="default" size="100%">Industrial area</style></keyword><keyword><style  face="normal" font="default" size="100%">Industrial research</style></keyword><keyword><style  face="normal" font="default" size="100%">Infant</style></keyword><keyword><style  face="normal" font="default" size="100%">ingestion</style></keyword><keyword><style  face="normal" font="default" size="100%">Internal exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Methylsiloxane</style></keyword><keyword><style  face="normal" font="default" size="100%">Orders of magnitude</style></keyword><keyword><style  face="normal" font="default" size="100%">plasma</style></keyword><keyword><style  face="normal" font="default" size="100%">pollutant source</style></keyword><keyword><style  face="normal" font="default" size="100%">pollution exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">residential area</style></keyword><keyword><style  face="normal" font="default" size="100%">Residential areas</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Assessment</style></keyword><keyword><style  face="normal" font="default" size="100%">Silicon</style></keyword><keyword><style  face="normal" font="default" size="100%">Silicon compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">siloxane</style></keyword><keyword><style  face="normal" font="default" size="100%">Siloxanes</style></keyword><keyword><style  face="normal" font="default" size="100%">skin absorption</style></keyword><keyword><style  face="normal" font="default" size="100%">sun</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107154986&amp;amp;doi=10.1016%2fj.envint.2021.106672&amp;amp;partnerID=40&amp;amp;md5=e0f4d4b4c2ac8d22188ce3d633a57673</style></url></web-urls></urls><publisher><style face="normal" font="default" size="100%">Elsevier Ltd</style></publisher><volume><style face="normal" font="default" size="100%">154</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Methylsiloxanes (MSs) are a significant source of indoor environmental pollution due to their high production level and widespread application, and pose a potential health risk. Given the special vulnerability of children to environmental contaminants, assessment of indoor MSs exposure in children is quite essential. In this study, we assessed internal exposure doses and external exposure levels of MSs in children from industrial and residential areas in southwestern China. Indoor air, indoor dust, and personal care product (PCP) samples were collected to evaluate indoor non-dietary MSs exposure in children through various pathways. The concentrations of MSs in indoor environments of industrial areas were approximately one to four orders of magnitude higher than those of residential areas. Sun protection products contained the highest concentrations of MSs. Relatively high levels of cyclic methylsiloxanes (CMSs) were found in plasma of children from industrial areas, which were one to two orders of magnitude higher than those in children from residential areas. The highest MSs levels in plasma were detected in infants (0–1 year), with values of 1.4 × 102 ng/mL and 1.3 × 102 ng/mL for CMSs (D4–D6) and linear methylsiloxanes (LMSs) (L5–L16), respectively. The internal exposure dose of infants in residential areas is driven by major unknown sources of MSs. The average daily doses via inhalation and dust ingestion in children from industrial areas were one to three orders of magnitude higher than in those from residential areas, indicating that these children should be considered a highly exposed population. Inhalation and dust ingestion were both major exposure pathways to MSs for children of all age groups in industrial areas, whereas dermal absorption from PCPs was the predominant exposure pathway for children of all age groups in residential areas (except for infants). Although the exposure risk to D4 and D5 was at an acceptable level for all children studied, the total daily exposure doses of these two cyclic compounds via inhalation for infants in the industrial areas was near the chronic reference dose. Meanwhile, MSs may accumulate in infant plasma within a short period of time (&amp;amp;lt;6 months). Therefore, infants should be the focus of greater attention in future research. As indoor environments may pose high risks for infants in industrial areas, they should be the focus of future research. © 2021</style></abstract><notes><style face="normal" font="default" size="100%">cited By 0</style></notes></record></records></xml>