<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gao, X.</style></author><author><style face="normal" font="default" size="100%">Thomsen, H.</style></author><author><style face="normal" font="default" size="100%">Y. Zhang</style></author><author><style face="normal" font="default" size="100%">Breitling, L. P.</style></author><author><style face="normal" font="default" size="100%">Brenner, H.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The impact of methylation quantitative trait loci (mQTLs) on active smoking-related DNA methylation changes</style></title><secondary-title><style face="normal" font="default" size="100%">Clin Epigenetics</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aged CpG Islands *DNA Methylation Epigenesis</style></keyword><keyword><style  face="normal" font="default" size="100%">DNA Smoking/*genetics *Active smoking *Epigenetic epidemiology *Methylation quantitative trait loci</style></keyword><keyword><style  face="normal" font="default" size="100%">Genetic Female Genetic Predisposition to Disease Humans Male Middle Aged *Polymorphism</style></keyword><keyword><style  face="normal" font="default" size="100%">Single Nucleotide *Quantitative Trait Loci Sequence Analysis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/28824732</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">1</style></number><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">87</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">{BACKGROUND: Methylation quantitative trait loci (mQTLs) are the genetic variants that may affect the DNA methylation patterns of CpG sites. However, their roles in influencing the disturbances of smoking-related epigenetic changes have not been well established. This study was conducted to address whether mQTLs exist in the vicinity of smoking-related CpG sites (+/- 50 kb) and to examine their associations with smoking exposure and all-cause mortality in older adults. RESULTS: We obtained DNA methylation profiles in whole blood samples by Illumina Infinium Human Methylation 450 BeadChip array of two independent subsamples of the ESTHER study (discovery set</style></abstract><work-type><style face="normal" font="default" size="100%">Journal Article</style></work-type><notes><style face="normal" font="default" size="100%">Gao, Xu Thomsen, Hauke Zhang, Yan Breitling, Lutz Philipp Brenner, Hermann eng Research Support, Non-U.S. Gov&amp;#039;t Germany Clin Epigenetics. 2017 Aug 17;9:87. doi: 10.1186/s13148-017-0387-6. eCollection 2017.</style></notes></record></records></xml>