@article {27266,
	title = {Short-term ambient particle radioactivity level and renal function in older men: Insight from the Normative Aging Study},
	journal = {Environ Int},
	volume = {131},
	year = {2019},
	note = {Gao, Xu Koutrakis, Petros Blomberg, Annelise J Coull, Brent Vokonas, Pantel Schwartz, Joel Baccarelli, Andrea A eng P30 ES009089/ES/NIEHS NIH HHS/ R01 ES021733/ES/NIEHS NIH HHS/ R01 ES025225/ES/NIEHS NIH HHS/ R01 ES027747/ES/NIEHS NIH HHS/ Research Support, N.I.H., Extramural Research Support, U.S. Gov\&$\#$039;t, Non-P.H.S. Netherlands Environ Int. 2019 Oct;131:105018. doi: 10.1016/j.envint.2019.105018. Epub 2019 Jul 20.},
	pages = {105018},
	type = {Journal Article},
	abstract = {{BACKGROUND: Whole-body and thoracic ionizing radiation exposure are both associated with the development of renal dysfunction. However, whether low-level environmental radiation from air pollution affects renal function remains unknown. OBJECTIVES: We investigated the association of particle radioactivity (PR) with renal function defined by the estimated glomerular filtration rate (eGFR) and chronic kidney disease (CKD) in the Normative Aging Study. METHODS: This longitudinal analysis included 2491 medical visits from 809 white males enrolled between 1999 and 2013. The eGFR was calculated using the CKD-EPI and MDRD equations, and CKD cases were identified as those with an eGFR \&lt;60mL/min/1.73m(2). Gross beta activity measured by five monitors of the U.S. Environmental Protection Agency\&$\#$039;s RadNet monitoring network was utilized to represent PR. RESULTS: Ambient PR levels from 1 to 28days prior to clinical visit demonstrated robust negative associations with both forms of eGFR, but not with the increased odds of CKD. An interquartile range higher 28-day average ambient PR level was significantly associated with 0.83-mL/min/1.73m(2) lower eGFR estimated by the CKD-EPI equation (95\% confidence interval: -1.46, -0.20},
	keywords = {Aged Glomerular Filtration Rate Humans Male *Radioactivity *Air pollution *ckd *Particle radioactivity *Renal function *eGFR},
	issn = {1873-6750 (Electronic) 0160-4120 (Linking)},
	doi = {10.1016/j.envint.2019.105018},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/31336254},
	author = {Gao, X. and Koutrakis, P. and Blomberg, A. J. and Coull, B. and Vokonas, P. and Schwartz, J. and Baccarelli, A. A.}
}
