<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Da, C. S.</style></author><author><style face="normal" font="default" size="100%">Wang, J. R.</style></author><author><style face="normal" font="default" size="100%">Yin, X. G.</style></author><author><style face="normal" font="default" size="100%">Fan, X. Y.</style></author><author><style face="normal" font="default" size="100%">Y. Liu</style></author><author><style face="normal" font="default" size="100%">Yu, S. L.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Highly Catalytic Asymmetric Addition of Deactivated Alkyl Grignard Reagents to Aldehydes</style></title><secondary-title><style face="normal" font="default" size="100%">Organic LettersOrganic LettersOrganic Letters</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Org Lett</style></alt-title><short-title><style face="normal" font="default" size="100%">Org. Lett.Org. Lett.</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">1,2-addition</style></keyword><keyword><style  face="normal" font="default" size="100%">amino-alcohols</style></keyword><keyword><style  face="normal" font="default" size="100%">aryl ketones</style></keyword><keyword><style  face="normal" font="default" size="100%">chiral ligands</style></keyword><keyword><style  face="normal" font="default" size="100%">complexes</style></keyword><keyword><style  face="normal" font="default" size="100%">enantioselective addition</style></keyword><keyword><style  face="normal" font="default" size="100%">prochiral aldehydes</style></keyword><keyword><style  face="normal" font="default" size="100%">titanium</style></keyword><keyword><style  face="normal" font="default" size="100%">transfer hydrogenation</style></keyword><keyword><style  face="normal" font="default" size="100%">zinc</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Dec 17</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">24</style></number><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">5578-5581</style></pages><isbn><style face="normal" font="default" size="100%">1523-7060</style></isbn><language><style face="normal" font="default" size="100%">English</style></language><abstract><style face="normal" font="default" size="100%">Generally used and highly reactive RMgBr reagents were effectively deactivated by bis[2-(N,N-dimethylamino)ethyl] ether and then were employed in the highly enantioselective addition of Grignard reagents to aldehydes. The reaction was catalyzed by the complex of commercially available (S)-BINOL and Ti(O&amp;#039;Pr-)(4) under mild conditions. Compared with the other observed Grignard reagents, alkyl Grignard reagents showed higher enantioselectivity and they achieved &amp;gt;99% ee.</style></abstract><accession-num><style face="normal" font="default" size="100%">WOS:000272461800004</style></accession-num><notes><style face="normal" font="default" size="100%">528QOTimes Cited:29Cited References Count:53</style></notes><auth-address><style face="normal" font="default" size="100%">Da, CsLanzhou Univ, Inst Biochem &amp;amp; Mol Biol, Sch Life Sci, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R ChinaLanzhou Univ, Inst Biochem &amp;amp; Mol Biol, Sch Life Sci, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R ChinaLanzhou Univ, Inst Biochem &amp;amp; Mol Biol, Sch Life Sci, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China</style></auth-address></record></records></xml>