<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yadav, J.</style></author><author><style face="normal" font="default" size="100%">Stanton, G. R.</style></author><author><style face="normal" font="default" size="100%">Fan, X. Y.</style></author><author><style face="normal" font="default" size="100%">Robinson, J. R.</style></author><author><style face="normal" font="default" size="100%">Schelter, E. J.</style></author><author><style face="normal" font="default" size="100%">Walsh, P. J.</style></author><author><style face="normal" font="default" size="100%">Pericas, M. A.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Asymmetric Allylation of Ketones and Subsequent Tandem Reactions Catalyzed by a Novel Polymer-Supported Titanium-BINOLate Complex</style></title><secondary-title><style face="normal" font="default" size="100%">Chemistry-a European JournalChemistry-a European Journal</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Chem-Eur J</style></alt-title><short-title><style face="normal" font="default" size="100%">Chem. Eur. J.</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">allylation</style></keyword><keyword><style  face="normal" font="default" size="100%">amino-acid</style></keyword><keyword><style  face="normal" font="default" size="100%">asymmetric catalysis</style></keyword><keyword><style  face="normal" font="default" size="100%">continuous-flow</style></keyword><keyword><style  face="normal" font="default" size="100%">enantioselective synthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">homoallylic alcohols</style></keyword><keyword><style  face="normal" font="default" size="100%">immobilization</style></keyword><keyword><style  face="normal" font="default" size="100%">n-oxide</style></keyword><keyword><style  face="normal" font="default" size="100%">organic catalysts</style></keyword><keyword><style  face="normal" font="default" size="100%">organocatalysts</style></keyword><keyword><style  face="normal" font="default" size="100%">pauson-khand reaction</style></keyword><keyword><style  face="normal" font="default" size="100%">supported catalysis</style></keyword><keyword><style  face="normal" font="default" size="100%">tandem processes</style></keyword><keyword><style  face="normal" font="default" size="100%">terminal alkynes</style></keyword><keyword><style  face="normal" font="default" size="100%">titanium</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jun 2</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">23</style></number><volume><style face="normal" font="default" size="100%">20</style></volume><pages><style face="normal" font="default" size="100%">7122-7127</style></pages><isbn><style face="normal" font="default" size="100%">0947-6539</style></isbn><language><style face="normal" font="default" size="100%">English</style></language><abstract><style face="normal" font="default" size="100%">By using a novel, simple, and convenient synthetic route, enantiopure 6-ethynyl-BINOL (BINOL=1,1-binaphthol) was synthesized and anchored to an azidomethylpolystyrene resin through a copper-catalyzed alkyne-azide cycloaddition (CuAAC) reaction. The polystyrene (PS)-supported BINOL ligand was converted into its diisopropoxytitanium derivative in situ and used as a heterogeneous catalyst in the asymmetric allylation of ketones. The catalyst showed good activity and excellent enantioselectivity, typically matching the results obtained in the corresponding homogeneous reaction. The allylation reaction mixture could be submitted to epoxidation by simple treatment with tert-butyl hydroperoxide (TBHP), and the tandem asymmetric allylation epoxidation process led to a highly enantioenriched epoxy alcohol with two adjacent quaternary centers as a single diastereomer. A tandem asymmetric allylation/Pauson-Khand reaction was also performed, involving simple treatment of the allylation reaction mixture with Co2(CO)8/N-methyl morpholine N-oxide. This cascade process resulted in the formation of two diastereomeric tricyclic enones in high yields and enantioselectivities.</style></abstract><accession-num><style face="normal" font="default" size="100%">WOS:000337574800037</style></accession-num><notes><style face="normal" font="default" size="100%">Aj3nyTimes Cited:5Cited References Count:66</style></notes><auth-address><style face="normal" font="default" size="100%">Inst Chem Res Catalonia, Tarragona 43007, SpainUniv Penn, Dept Chem, P Roy &amp;amp; Diana Vagelos Labs, Philadelphia, PA 19104 USAUniv Barcelona, Dept Quim Organ, E-08028 Barcelona, Spain</style></auth-address></record></records></xml>