<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Zheng, J. S.</style></author><author><style face="normal" font="default" size="100%">Liu, H.</style></author><author><style face="normal" font="default" size="100%">Ong, K. K.</style></author><author><style face="normal" font="default" size="100%">Huang, T.</style></author><author><style face="normal" font="default" size="100%">Guan, Y.</style></author><author><style face="normal" font="default" size="100%">Huang, Y.</style></author><author><style face="normal" font="default" size="100%">Yang, B.</style></author><author><style face="normal" font="default" size="100%">F. Wang</style></author><author><style face="normal" font="default" size="100%">D. Li</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Maternal Blood Pressure Rise During Pregnancy and Offspring Obesity Risk at 4 to 7 Years Old: The Jiaxing Birth Cohort</style></title><secondary-title><style face="normal" font="default" size="100%">J Clin Endocrinol MetabJ Clin Endocrinol MetabJ Clin Endocrinol Metab</style></secondary-title><alt-title><style face="normal" font="default" size="100%">The Journal of clinical endocrinology and metabolism</style></alt-title><short-title><style face="normal" font="default" size="100%">The Journal of clinical endocrinology and metabolismThe Journal of clinical endocrinology and metabolism</style></short-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Age of Onset</style></keyword><keyword><style  face="normal" font="default" size="100%">Blood Pressure/*physiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Child, Preschool</style></keyword><keyword><style  face="normal" font="default" size="100%">China/epidemiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Cohort Studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypertension, Pregnancy-Induced/*epidemiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Infant, Newborn</style></keyword><keyword><style  face="normal" font="default" size="100%">Pediatric Obesity/*epidemiology/*etiology</style></keyword><keyword><style  face="normal" font="default" size="100%">Pregnancy</style></keyword><keyword><style  face="normal" font="default" size="100%">Prenatal Exposure Delayed Effects/*epidemiology/physiopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Risk Factors</style></keyword><keyword><style  face="normal" font="default" size="100%">Young Adult</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov 1</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">11</style></number><edition><style face="normal" font="default" size="100%">2017/11/09</style></edition><volume><style face="normal" font="default" size="100%">102</style></volume><pages><style face="normal" font="default" size="100%">4315-4322</style></pages><isbn><style face="normal" font="default" size="100%">1945-7197 (Electronic)0021-972X (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Context: Maternal hypertensive disorders during pregnancy are suggested to affect obesity risk in offspring. However, little is known about the prospective association of rise in maternal blood pressure within normal range during pregnancy with this risk for obesity. Objective: To clarify the associations of diastolic and systolic blood pressure during pregnancy among normotensive women with the risk for obesity in offspring. Design: Prospective cohort study. Setting: Southeast China. Participants: Up to 2013, a total of 88,406 mother-child pairs with anthropometric measurements of offspring age 4 to 7 years were included in the present analysis. Main Outcome Measures: Overweight/obesity risk in offspring. Results: Among normotensive women, second- and third-trimester diastolic and systolic blood pressures were positively associated with risk for overweight/obesity in offspring: odds ratios per 10-mm Hg higher second- and third-trimester diastolic blood pressure were 1.05 [95% confidence interval (CI), 1.01 to 1.09] and 1.05 (95% CI, 1.02 to 1.10), respectively, and for systolic blood pressure were 1.08 (95% CI, 1.05 to 1.11) and 1.06 (95% CI, 1.03 to 1.09). Each 10-mm Hg greater rise in blood pressure between first and third trimesters was associated with a higher risk for offspring overweight/obesity: diastolic, 1.06 (95% CI, 1.01 to 1.10); systolic, 1.05 (95% CI, 1.02 to 1.07). Among all women (combining normotensive and hypertensive women), maternal hypertension in the second and third trimesters was associated with 49% and 14% higher risks for overweight/obesity in offspring, respectively. Conclusions: These results suggest that rise in maternal blood pressure during pregnancy and hypertension during pregnancy, independent of maternal body size before pregnancy, are risk factors for offspring childhood obesity.</style></abstract><work-type><style face="normal" font="default" size="100%">Research Support, Non-U.S. Gov&amp;#039;t</style></work-type><accession-num><style face="normal" font="default" size="100%">29117369</style></accession-num><notes><style face="normal" font="default" size="100%">Zheng, Ju-ShengLiu, HuijuanOng, Ken KHuang, TaoGuan, YuhongHuang, YuanYang, BoWang, FengleiLi, DuoMC_UU_12015/2/Medical Research Council/United KingdomMC_UU_12015/5/Medical Research Council/United KingdomJ Clin Endocrinol Metab. 2017 Nov 1;102(11):4315-4322. doi: 10.1210/jc.2017-01500.</style></notes><custom2><style face="normal" font="default" size="100%">6112413</style></custom2><auth-address><style face="normal" font="default" size="100%">Institute of Nutrition &amp;amp; Health, Qingdao University, Qingdao 26071, China.Medical Research Council Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, United Kingdom.Jiaxing Maternity and Child Health Care Hospital, Jiaxing 314051, China.Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.Saw Swee Hock School of Public Health, National University of Singapore, Singapore 117549.EPSRC Centre for Mathematical and Statistical Analysis of Multimodal Clinical Imaging, University of Cambridge, Cambridge CB3 0WB, United Kingdom.Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, China.</style></auth-address></record></records></xml>