@article {31011,
	title = {Effect of sulfamethoxazole on aerobic denitrification by strain Pseudomonas stutzeri PCN-1},
	journal = {Bioresource TechnologyBioresource Technology},
	volume = {235},
	year = {2017},
	note = {Times Cited: 49521873-2976},
	month = {Jul},
	pages = {325-331},
	abstract = {Sulfamethoxazole (SMX), as a common sulfonamide antibiotic, was reported to affect conventional anaerobic denitrification. This study presented effects of SMX on aerobic denitrification by an aerobic denitrifier strain Pseudomonas stutzeri PCN-1. Results demonstrated serious inhibition of N2O reduction as SMX reached 4 mu g/L, leading to higher N2O emission ratio (251-fold). Increase of SMX (similar to 8 mu g/L) would induce highest nitrite accumulation (95.3 mg/L) without reduction, and severe inhibition of nitrate reduction resulted in lower nitrate removal rate (0.15 mg/L/h) as SMX reached 20 mu g/L. Furthermore, corresponding inhibition of SMX on denitrifying genes expression (nosZ \&gt; nirS \&gt; cnorB \&gt; napA) was found with a time-lapse expression between nosZ and cnorB. Meanwhile, the decline in electron transport activity and active microbial biomass of strain PCN-1 was revealed. The insight into mechanism of SMX influence on aerobic denitrifier is of particular significance to upgrade nitrogen removal process in antibiotics-containing wastewater treatment plant. (C) 2017 Elsevier Ltd. All rights reserved.},
	isbn = {0960-8524},
	author = {Gui, Mengyao and Qian Chen and Ni, Jinren}
}
