科研成果

2008
Jiang L, Fan J, Bai L, Wang Y, Chen Y, Yang L, Chen L, Xu T. Direct quantification of fusion rate reveals a distal role for AS160 in insulin-stimulated fusion of GLUT4 storage vesicles. Journal of Biological Chemistry [Internet]. 2008;(13):8508-8516. 访问链接
Wei D, Jiang X, Zhou L, Chen J, Chen Z, He C, Yang K, Liu Y, Pei J, Lai L. Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching. Journal of Medicinal Chemistry [Internet]. 2008;(24):7882-7888. 访问链接
Hu X, Xu X, Huang Y, Fassett J, Flagg TP, Zhang Y, Nichols CG, Bache RJ, Chen Y. Disruption of sarcolemmal atp-sensitive potassium channel activity impairs the cardiac response to systolic overload. Circulation Research [Internet]. 2008;(9):1009-1017. 访问链接
Qu T, Xiao Z, Gong M, Huang Y, Li X, Wu X. Distance dependent head-related transfer function database of KEMAR, in International Conference on Audio, Language and Image Processing.; 2008.
Deng W, Cao A, Lai L. Distinguishing the cross-β spine arrangements in amyloid fibrils using FRET analysis. Protein Science [Internet]. 2008;(6):1102-1105. 访问链接
Li Z, Gao Y, Jiao Z, Wu N, Wang DZ, Yang Z. Diversity-oriented synthesis of fused pyran γ-lactones via an efficient Pd-thiourea-catalyzed alkoxycarbonylative annulation. Organic Letters [Internet]. 2008;(22):5163-5166. 访问链接
Lu L, Fang Y, Wang X. Drug abuse in China: Past, present and future. Cellular and Molecular Neurobiology [Internet]. 2008;(4):479-490. 访问链接
Zhai H, Li Y, Wang X, Lu L. Drug-induced alterations in the extracellular signal-regulated kinase (ERK) signalling pathway: Implications for reinforcement and reinstatement. Cellular and Molecular Neurobiology [Internet]. 2008;(2):157-172. 访问链接
Chen X-W, Feng Y-Q, Hao C-J, Guo X-L, He X, Zhou Z-Y, Guo N, Huang H-P, Xiong W, Zheng H, et al. DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release. Journal of Cell Biology [Internet]. 2008;(5):791-801. 访问链接
Xie Z, Li X, Glover BJ, Bai SN, Rao G-Y, Luo J, Yang J. Duplication and functional diversification of HAP3 genes leading to the origin of the seed-developmental regulatory gene, LEAFY COTYLEDON1 (LEC1), in nonseed plant genomes. Molecular Biology and Evolution [Internet]. 2008;(8):1581-1592. 访问链接
Liu Y-X, Wang J, Guo J, Wu J, Lieberman HB, Yin Y. DUSP1 is controlled by p53 during the cellular response to oxidative stress. Molecular Cancer Research [Internet]. 2008;(4):624-633. 访问链接
周昌令, 唐湘. DWG 格式→ ICEMCFD 文件格式的转换. 水动力学研究与进展: A 辑. 2008:843–846.
Yao X-Q, Zhu H, She Z-S. A dynamic Bayesian network approach to protein secondary structure prediction. BMC Bioinformatics [Internet]. 2008. 访问链接
SONG W-J, ZHOU C-ling, Cui J, SHANG Q, ZHANG B. Dynamic Dual-Binding: A Solution to ARP Cache Poisoning. Periodical of Ocean University of China. 2008:S1.
Bai H, Ma W, Liu S, Lai L. Dynamic property is a key determinant for protein-protein interactions. Proteins: Structure, Function and Genetics [Internet]. 2008;(4):1323-1331. 访问链接
Chin C-S, Chubukov V, Jolly ER, DeRisi J, Li H. Dynamics and design principles of a basic regulatory architecture controlling metabolic pathways. PLoS Biology [Internet]. 2008;(6):1343-1356. 访问链接
Liu Y, Guo H, Yu Y, Dai Y, Zhou F. Ecological-economic modeling as a tool for watershed management: A case study of Lake Qionghai watershed, China. LIMNOLOGICA. 2008;38:89-104.Abstract
This paper presents an ecological-economic model for a lake and its watershed systems. We describe the linkage between the watershed system and the lake aquatic ecosystem and the modeling process. The take-watershed system was divided into six subsystems: social system, economic system, terrestrial ecosystem, lake water system, pollutant system, and lake aquatic ecosystem. The model equations were constructed based on five main assumptions. The Lake Qionghai watershed in southwestern China, which is undergoing rapid eutrophication, was used as a case study. The targeted goals for total phosphorus (TP) and chlorophyll a (Chl a) concentrations in the lake in 2015 are 0.025 and 10.0 mg m(-3), respectively. We present two scenarios from 2004 to 2015 based on the ecological-economic model. In both scenarios, the TP and Chl a concentrations in the lake are predicted to increase under the effects of watershed pressures and the targeted goals cannot be met. The application of techniques to reduce pollutants loading and the corresponding pollutants reductions are reflected again in the constructed model. The model predicts that TP and Chl a concentrations will decrease to 0.024 and 7.71 mg m(-3), respectively, which meet the targeted thresholds. The model results provide directions for local government management of watersheds and lake aquatic ecosystem restoration. (C) 2007 Elsevier GmbH. All rights reserved.
Liu Y, Guo HC, Yu YJ, Dai YL, Zhou F. Ecological-economic modeling as a tool for watershed management: A case study of Lake Qionghai watershed, China. Limnologica. 2008;38:89-104.Abstract
This paper presents an ecological-economic model for a lake and its watershed systems. We describe the linkage between the watershed system and the lake aquatic ecosystem and the modeling process. The take-watershed system was divided into six subsystems: social system, economic system, terrestrial ecosystem, lake water system, pollutant system, and lake aquatic ecosystem. The model equations were constructed based on five main assumptions. The Lake Qionghai watershed in southwestern China, which is undergoing rapid eutrophication, was used as a case study. The targeted goals for total phosphorus (TP) and chlorophyll a (Chl a) concentrations in the lake in 2015 are 0.025 and 10.0 mg m(-3), respectively. We present two scenarios from 2004 to 2015 based on the ecological-economic model. In both scenarios, the TP and Chl a concentrations in the lake are predicted to increase under the effects of watershed pressures and the targeted goals cannot be met. The application of techniques to reduce pollutants loading and the corresponding pollutants reductions are reflected again in the constructed model. The model predicts that TP and Chl a concentrations will decrease to 0.024 and 7.71 mg m(-3), respectively, which meet the targeted thresholds. The model results provide directions for local government management of watersheds and lake aquatic ecosystem restoration. (C) 2007 Elsevier GmbH. All rights reserved.
Xu X, Fassett J, Hu X, Zhu G, Lu Z, Li Y, Schnermann J, Bache RJ, Chen Y. Ecto-5′ -nucleotidase deficiency exacerbates pressure-overload- induced left ventricular hypertrophy and dysfunction. Hypertension [Internet]. 2008;(6):1557-1564. 访问链接
Gu Y. Effect of [Cl-]i on ENaC activity from mouse cortical collecting duct cells. Journal of Cellular Physiology [Internet]. 2008;(2):453-457. 访问链接

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