This paper presents a reflectometer with an integrated transducer as a high-integration miniaturized sensor for dielectric spectroscopy at 240 GHz in SiGe BiCMOS technology. The reflectometer consists of a signal generation component using 240-GHz multiplier chains, side-coupled directive couplers and a two-channel heterodyne receiver. Readout of the transducer upon exposure to liquids is performed by the measurement of its reflected signal using an external excitation source. The experimental dielectric sensing is demonstrated by using a binary methanol-ethanol mixture placed on the proposed on-chip dielectric sensor in the assembled printed circuit board.
This article presents a reflectometer-based on-chip dielectric sensor with integrated transducers at 240 GHz. The chip simplifies the measurement of a vector network analyzer (VNA) to sense the incident and reflected waves by using two heterodyne mixer-based receivers with a dielectric sensing element. Radio frequency (RF) and local oscillator (LO) submillimeter waves are generated by two frequency multiplier chains, respectively. Two back-to-back identical differential side-coupled directive couplers are proposed to separate the incident and reflected signals and couple them to mixers. Both transmission line and coplanar stripline transducers are proposed and integrated with reflectometer to investigate the sensitivity of dielectric sensors. The latter leads to a larger power variation of the reflectometer by providing more sufficient operating bands for the magnitude and phase slope of S11 . The readout of the transducers upon exposure to liquids is performed by the measurement of their reflected signals using two external excitation sources. The experimental dielectric sensing is demonstrated by using binary methanol–ethanol mixture placed on the proposed on-chip dielectric sensor in the assembled printed circuit board. It enables a maximum 8 dB of the power difference between the incident and reflected channels on the measurement of liquid solvents. Both chips occupy an area of 4.03 mm 2 and consume 560 mW. Along with a wide operational frequency range from 200 to 240 GHz, this simplified one-port-VNA-based on-chip device makes it feasible for the use of handle product and suitable for the submillimeter-wave dielectric spectroscopy applications.
2D/1D graphitic carbon nitride hybridized with titanate nanotubes (g-C3N4/TNTs) was prepared through a hydrothermal reaction–calcination method. The photocatalyst exhibited high degradation efficiency for sulfamethazine (SMT) through photocatalysis under simulated solar light. The optimized material was composed of anatase, rutile, titanate and g-C3N4 crystalline phases. In situ transformation of titanate to anatase and rutile with specific content proportion (∼80:20, P25-type composition) leaded to formation of nanoscale “hot spots” at rutile–anatase–titanate interfaces, and then subsequent charge transfer occurred. Large specific surface area of TNTs as skeleton resulted in high-efficient interface reaction, while heterojunction with g-C3N4 further extended the adsorption to visible light region and retarded electron-hole pairs recombination. Density functional theory (DFT) calculation indicated the SMT sites with high Fukui nucleophilic (f-) index prefered to be attacked by radacils. Reduced toxicity of SMT degradation intermediates, good reusability and stability of g-C3N4/TNTs all suggested the great application potential in practical water treatment area.
A 480-GHz sensor consists of signal stimulus and the transducer element as well as a subharmonic mixer in a 130-nm SiGe BiCMOS technology is reported. It features a mixer-first architecture based on down-conversion subharmonic mixer, an local oscillator (LO) chain at 240-GHz using a frequency doubler with variable-gain characterization, and a 480-GHz RF chain, making the fully integrated 480-GHz receiver possible. In a frequency range of 210–270 GHz at a maximum of 1.5-V supply offset, the LO chain has a 14-dB power-level variation, comprising with a 120-GHz frequency quadrupler, a power amplifier, and a variable frequency doubler. The proposed subharmonic receiver is driven by the RF and LO chain with a multiplier factor of 16 and 8, respectively. In this way, 480-GHz signal is generated, fed through the transducer, and hetero-mixed at subharmonic mixer. The measured output power difference is adjustable over 8 dB. Along with the intermediate frequency (IF) bandwidth of 20 GHz, the wide RF bandwidth makes it suitable for submillimetre-wave receiver-based dielectric spectroscopy applications. The chip occupies an area of 2.2 mm 2 and consumes 290 mW.
Chronic obstructive pulmonary disease (COPD) is a frequent diagnosis in older individuals and contributor to global morbidity and mortality. Given the link between lung disease and aging, we need to understand how molecular indicators of aging relate to lung function and disease. Using data from the population-based KORA (Cooperative Health Research in the Region of Augsburg) surveys, we associated baseline epigenetic (DNA methylation) age acceleration with incident COPD and lung function. Models were adjusted for age, sex, smoking, height, weight, and baseline lung disease as appropriate. Associations were replicated in the Normative Aging Study. Of 770 KORA participants, 131 developed incident COPD over 7 years. Baseline accelerated epigenetic aging was significantly associated with incident COPD. The change in age acceleration (follow-up - baseline) was more strongly associated with COPD than baseline aging alone. The association between the change in age acceleration between baseline and follow-up and incident COPD replicated in the Normative Aging Study. Associations with spirometric lung function parameters were weaker than those with COPD, but a meta-analysis of both cohorts provide suggestive evidence of associations. Accelerated epigenetic aging, both baseline measures and changes over time, may be a risk factor for COPD and reduced lung function.
Existing enhancement methods are empirically expected to help the high-level end computer vision task: however, that is observed to not always be the case in practice. We focus on object or face detection in poor visibility enhancements caused by bad weathers (haze, rain) and low light conditions. To provide a more thorough examination and fair comparison, we introduce three benchmark sets collected in real-world hazy, rainy, and low-light conditions, respectively, with annotated objects/faces. We launched the UG2+ challenge Track 2 competition in IEEE CVPR 2019, aiming to evoke a comprehensive discussion and exploration about whether and how low-level vision techniques can benefit the high-level automatic visual recognition in various scenarios. To our best knowledge, this is the first and currently largest effort of its kind. Baseline results by cascading existing enhancement and detection models are reported, indicating the highly challenging nature of our new data as well as the large room for further technical innovations. Thanks to a large participation from the research community, we are able to analyze representative team solutions, striving to better identify the strengths and limitations of existing mindsets as well as the future directions.
Covalent organic frameworks (COFs) have recently been demonstrated to have great application potentials in water treatment. Their photocatalytic performance towards bacterial disinfection and organic pollutant degradation yet has seldom been investigated. In this study, AgI modified COFs (using 2,5-diaminopyridine and 1,3,5-triformylphloroglucinol as precursors) (COF-PD/AgI) were fabricated and their applications to photocatalytically disinfect bacteria and degrade organic pollutants were investigated. COF-PD/AgI exhibited effective photocatalytic performance towards Escherichia coli disinfection and organic pollutant (Rhodamine B and acetaminophen) degradation. SEM images were employed to investigate cell disinfection process, while theoretical density functional theory (DFT) calculation and intermediates determination were used to elucidate organic pollutant degradation processes. Scavenger experiments, ESR spectra and chemical probes experiments confirmed O2−, h+ and OH played important roles in the photocatalytic process. The formation of dual-band Z-scheme heterojunction improved photocatalytic performance. COF-PD/AgI remained high photocatalytic activity in the four consecutive cycles and could serve as a promising photocatalyst for water purification.
Snowpack stores cold-season precipitation to meet warm-season water demand. Climate change threatens to disturb this balance by altering the fraction of precipitation falling as snow and the timing of snowmelt, which may have profound effects on food production in basins where irrigated agriculture relies heavily on snowmelt runoff. Here, we analyse global patterns of snowmelt and agricultural water uses to identify regions and crops that are most dependent on snowmelt water resources. We find hotspots primarily in high-mountain Asia (the Tibetan Plateau), Central Asia, western Russia, western US and the southern Andes. Using projections of sub-annual runoff under warming scenarios, we identify the basins most at risk from changing snowmelt patterns, where up to 40% of irrigation demand must be met by new alternative water supplies under a 4 °C warming scenario. Our results highlight basins and crops where adaptation of water management and agricultural systems may be especially critical in a changing climate.
