科研成果

2010
Zheng M, Xiao R-P. Role of mitofusin 2 in cardiovascular oxidative injury. Journal of Molecular Medicine [Internet]. 2010;(10):987-991. 访问链接 SCI被引用次数:12.
Peng W, Zhang Y, Zheng M, Cheng H, Zhu W, Cao C-M, Xiao R-P. Cardioprotection by CaMKII-δB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70. Circulation Research [Internet]. 2010;(1):102-110. 访问链接 SCI被引用次数:85.
2009
Zheng M, Cheng H, Li X, Zhang J, Cui L, Ouyang K, Han L, Zhao T, Gu Y, Dalton ND, et al. Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death. Human Molecular Genetics [Internet]. 2009;(4):701-713. 访问链接 SCI被引用次数:68.
2008
Sheikh F, Raskin A, Chu P-H, Lange S, Domenighetti AA, Zheng M, Liang X, Zhang T, Yajima T, Gu Y, et al. An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. Journal of Clinical Investigation [Internet]. 2008;(12):3870-3880. 访问链接
Chen C-lei, Shen T, Zheng M, Guo Y-hong, Zhu X-jun, Chen G-hui. Inhibition of cardiac hypertrophy by mitofusin 2 in neonatal rat cardiomyocytes. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences [Internet]. 2008;(5):528-532. 访问链接
Wang W, Fang H, Groom L, Cheng A, Zhang W, Liu J, Wang X, Li K, Han P, Zheng M, et al. Superoxide Flashes in Single Mitochondria. Cell [Internet]. 2008;(2):279-290. 访问链接
2007
Shen T, Zheng M, Cao C, Chen C, Tang J, Zhang W, Cheng H, Chen K-H, Xiao R-P. Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis. Journal of Biological Chemistry [Internet]. 2007;(32):23354-23361. 访问链接 SCI被引用次数:131.
2006
Xiao R-P, Zhu W, Zheng M, Cao C, Zhang Y, Lakatta EG, Han Q. Subtype-specific α1- and β-adrenoceptor signaling in the heart. Trends in Pharmacological Sciences [Internet]. 2006;(6):330-337. 访问链接 SCI被引用次数:120.
2005
Zheng M, Zhu W, Han Q, Xiao R-P. Emerging concepts and therapeutic implications of β-adrenergic receptor subtype signaling. Pharmacology and Therapeutics [Internet]. 2005;(3):257-268. 访问链接 SCI被引用次数:80.
Zhu W, Zeng X, Zheng M, Xiao R-P. The enigma of β2-adrenergic receptor Gi signaling in the heart: The good, the bad, and the ugly. Circulation Research [Internet]. 2005;(6):507-509. 访问链接 SCI被引用次数:56.
Zheng M, Reynolds C, Jo S-H, Wersto R, Han Q, Xiao R-P. Intracellular acidosis-activated p38 MAPK signaling and its essential role in cardiomyocyte hypoxic injury. FASEB Journal [Internet]. 2005;(1):109-111. 访问链接
2004
Zheng M, Hou R, Han Q, Xiao R-P. Different regulation of ERK1/2 activation by β-adrenergic receptor subtypes in adult mouse cardiomyocytes. Heart Lung and Circulation [Internet]. 2004;(2):179-183. 访问链接
Zheng M, Hou R, Xiao R-P. Acidosis-induced p38 MAPK activation and its implication in regulation of cardiac contractility. Acta Pharmacologica Sinica [Internet]. 2004;(10):1299-1305. 访问链接
Zheng M, Han Q-D, Xiao R-P. Distinct beta-adrenergic receptor subtype signaling in the heart and their pathophysiological relevance. Sheng li xue bao [Acta physiologica Sinica] [Internet]. 2004;(1):1-15. 访问链接
Leblais V, Jo S-H, Chakir K, Maltsev V, Zheng M, Crow MT, Wang W, Lakatta EG, Xiao R-P. Phosphatidylinositol 3-kinase offsets cAMP-mediated positive inotropic effect via inhibiting Ca2+ influx in cardiomyocytes. Circulation Research [Internet]. 2004;(12):1183-1190. 访问链接 SCI被引用次数:46.
Xiao R-P, Zhu W, Zheng M, Chakir K, Bond R, Lakatta EG, Cheng H. Subtype-specific β-adrenoceptor signaling pathways in the heart and their potential clinical implications. Trends in Pharmacological Sciences [Internet]. 2004;(7):358-365. 访问链接 SCI被引用次数:116.
2003
Yin F, Li P, Zheng M, Chen L, Xu Q, Chen K, Wang Y-Y, Zhang Y-Y, Han C. Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart. Journal of Biological Chemistry [Internet]. 2003;(23):21070-21075. 访问链接 SCI被引用次数:56.
2002
Liao P, Wang S-Q, Wang S, Zheng M, Zheng M, Zhang S-J, Cheng H, Wang Y, Xiao R-P. p38 mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes. Circulation Research [Internet]. 2002;(2):190-196. 访问链接 SCI被引用次数:133.
2001
Zhu W-Z, Zheng M, Koch WJ, Lefkowitz RJ, Kobilka BK, Xiao R-P. Dual modulation of cell survival and cell death by β2-adrenergic signaling in adult mouse cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America [Internet]. 2001;(4):1607-1612. 访问链接
2000
Zheng M, Zhang S-J, Zhu W-Z, Ziman B, Kobilka BK, Xiao R-P. β2-adrenergic receptor-induced p38 MAPK activation is mediated by protein kinase A rather than by Gi or Gβγ in adult mouse cardiomyocytes. Journal of Biological Chemistry [Internet]. 2000;(51):40635-40640. 访问链接

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