@article {doi:10.1021/acs.est.3c03768,
	title = {Effects of Antibiotic Resistance Genes and Antibiotics on the Transport and Deposition Behaviors of Bacteria in Porous Media},
	journal = {Environmental Science \&amp; Technology},
	volume = {57},
	number = {28},
	year = {2023},
	note = {PMID: 37406198},
	pages = {10426-10437},
	abstract = {Antibiotics present in the natural environment would induce the generation of antibiotic-resistant bacteria (ARB), causing great environmental risks. The effects of antibiotic resistance genes (ARGs) and antibiotics on bacterial transport/deposition in porous media yet are unclear. By using E. coli without ARGs as antibiotic-susceptible bacteria (ASB) and their corresponding isogenic mutants with ARGs in plasmids as ARB, the effects of ARGs and antibiotics on bacterial transport in porous media were examined under different conditions (1{\textendash}4 m/d flow rates and 5{\textendash}100 mM NaCl solutions). The transport behaviors of ARB were comparable with those of ASB under antibiotic-free conditions, indicating that ARGs present within cells had negligible influence on bacterial transport in antibiotic-free solutions. Interestingly, antibiotics (5{\textendash}1000 μg/L gentamicin) present in solutions increased the transport of both ARB and ASB with more significant enhancement for ASB. This changed bacterial transport induced by antibiotics held true in solution with humic acid, in river water and groundwater samples. Antibiotics enhanced the transport of ARB and ASB in porous media via different mechanisms (ARB: competition of deposition sites; ASB: enhanced motility and chemotaxis effects). Clearly, since ASB are likely to escape sites containing antibiotics, these locations are more likely to accumulate ARB and their environmental risks would increase.},
	doi = {10.1021/acs.est.3c03768},
	url = {https://doi.org/10.1021/acs.est.3c03768},
	author = {Wang, Shuai and He, Lei and Mengya Zhang and Su, Xiangyu and Fuyang Liu and Qian Chen and Yang, Jinshui and Meiping Tong}
}
