@article {15632,
	title = {Acute Changes in Heart Rate Variability in Subjects With Diabetes Following a Highway Traffic Exposure},
	journal = {Journal of Occupational and Environmental Medicine},
	volume = {52},
	number = {3},
	year = {2010},
	note = {567xaTimes Cited:20Cited References Count:44},
	month = {Mar},
	pages = {324-331},
	abstract = {Objective: To pilot a protocol to evaluate acute cardiovascular effects in in-vehicle exposure to traffic air pollutants in people with diabetes. Methods: Twenty-one volunteers with type 2 diabetes were passengers on 90- to 110-minute car rides on a busy highway. We measured in-vehicle particle number and mass (PM(2.5)) nitrogen dioxide, and carbon monoxide and heart rate, heart rate variability (HRV), and blood pressure. Results: Compared with pre-ride measurements, we found a decrease in high frequency (HF) HRV from pre-ride to next day (ratio 0.66, 95\% CI = 0.47 to 0.93) and an increase in low frequency to HF ratio at post-ride (ratio 1.92, 95\% CI = 1.21 to 3.05) at post-ride. Interquartile range increases in measured pollutants were associated with next-day decreases in HR HRV. Conclusions: This protocol appears useful for assessing acute adverse cardiovascular effects of in-vehicle exposures among people who have diabetes.},
	keywords = {ambient pollution, blood-pressure, cardiac autonomic neuropathy, circadian patterns, myocardial-infarction, Oxidative Stress, particulate air-pollution, time-series, ultrafine particles, ventricular-arrhythmias},
	isbn = {1076-2752},
	author = {Laumbach, R. J. and Rich, D. Q. and Gandhi, S. and Amorosa, L. and Schneider, S. and Zhang, J. F. and Ohman-Strickland, P. and Gong, J. and Lelyanov, O. and Kipen, H. M.}
}
